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Cancer risk slightly higher for women in discontinued hormone treatment trial

A follow up study of participants in the Women's Health Initiative (WHI) clinical trial led by a University of North Carolina at Chapel Hill researcher has found that women who were taking the combined hormone therapy of estrogen plus progestin may have an increased risk of cancer since the intervention was stopped, compared to participants in the trial's placebo group.

6 Mar 2008

Arsenic aids tumor imaging when joined to cancer-homing drug

Arsenic linked to a drug that binds to the blood vessels of cancerous tumors provides a powerful imaging agent that could one day allow physicians to detect hard-to-find tumors and more closely monitor cancer's response to therapy, researchers at UT Southwestern Medical Center have found.

6 Mar 2008

Biomagnets could be used to destroy cancer

Researchers in the UK have developed a method to strengthen bacteria-produced magnets or biomagnets that can be guided to tumours and destroy cancer cells.

5 Mar 2008

Watery pools in bone marrow key to psoriatic arthritic damage

Researchers have learned more about how a leading drug prevents certain types of arthritis from eating away at bone, according to a study published in the March edition of the Annals of the Rheumatic Diseases.

4 Mar 2008

Experimental cancer drug MI-219 promising in preclinical studies

Researchers have long searched for a novel cancer drug that activates a certain protein to kill tumor cells.

4 Mar 2008

Cell proteins could offer a future drug target against weight gain

Two cell proteins that relax the gut and help accommodate a big meal have been identified by UCL (University College London) scientists.

4 Mar 2008

Cause of depression and anxiety unknown not chemical

The theory that depression is caused by a chemical imbalance is often presented in the media as fact even though there is little scientific evidence to support it, according to a new study co-authored by a Florida State University visiting lecturer.

4 Mar 2008

Researchers working to curb impulsivity in children with ADHD

Central Michigan University researchers are one step closer to helping children with attention deficit/hyperactivity disorder improve their self-control.

4 Mar 2008

Abuse of prescription medications linked to drug abuse among college students

College students who take frequently abused medications without a prescription appear to have a higher risk for drug abuse than those who use such therapies for medical reasons, according to a report in the March issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

4 Mar 2008

Guidelines for von Willebrand disease diagnosis and management

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health today issued the first clinical guidelines in the United States for the diagnosis and management of von Willebrand Disease (VWD), the most common inherited bleeding disorder.

4 Mar 2008

Genetic variations increase risk of anxiety disorders

Massachusetts General Hospital (MGH) researchers - in collaboration with scientists at the University of California at San Diego and Yale University - have discovered perhaps the strongest evidence yet linking variation in a particular gene with anxiety-related traits.

4 Mar 2008

FDA approves Aloxi injection for prevention of postoperative nausea and vomiting

Eisai Corporation of North America, its U.S. subsidiary, MGI PHARMA, INC., and Helsinn Healthcare SA today announced that the U.S. Food and Drug Administration (FDA) has approved Aloxi (palonosetron hydrochloride) injection for the prevention of postoperative nausea and vomiting (PONV) for up to 24 hours following surgery.

4 Mar 2008

Estradiol hormone protects against hearing loss

The "female sex hormone" estradiol is present in both men and women, and is generated from testosterone in men by the protein aromatase.

4 Mar 2008

Discovery of key molecular mechanism associated with cystic fibrosis

Researchers from the University of North Carolina at Chapel Hill have identified a key molecular mechanism that may account for the development of cystic fibrosis.

4 Mar 2008

Clinical depression raises risk of death for heart attack patients years after attack

Depressed heart attack patients have a higher risk for sudden death in the months following a heart attack.

4 Mar 2008

Ten years down the line a pill to cure obesity

British scientists say they may have found a new way to treat obesity by stopping the stomach from expanding.

4 Mar 2008

Nanotechnology advances brain cancer detection and therapy

Brain cancer is one of the most aggressive and lethal of malignancies, made even more difficult to treat by the fact that most anticancer drugs have a hard time even getting to the tumors.

3 Mar 2008

Preclinical antitumor efficacy evaluation of dendrimer-based methotrexate conjugates

Although a variety of nanoparticles continue to show promise for improving cancer imaging and therapy, regulators and drug developers are concerned that these delivery systems may prove difficult to manufacture on a consistent basis, which is key for any agent designed for use in humans.

3 Mar 2008

Fluorescent nanoparticles image tumor marker in animals

Since 2004 the U.S. Food and Drug Administration has approved three new-generation anticancer therapies that target epidermal growth factor receptor (EGFR), a protein that is greatly overexpressed on certain types of tumors, including some forms of colorectal and lung cancer.

3 Mar 2008