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Researchers show how liver cancer cells hijack circadian clock machinery to divide and spread

The most common type of liver cancer, hepatocellular carcinoma (HCC), is already the third leading cause of cancer-related deaths globally - and cases are on the rise, both in the U.S. and worldwide.

6 Jan 2023

Brief tele-cognitive behavioral therapy for head and neck cancer survivors with body-image distress shows promising results

Talking, smiling, eating together – these are all social activities that are inherent to the human experience. But for some head and neck cancer survivors, they are dreaded tasks.

6 Jan 2023

Study details the “immunometabolic editing” mechanism of tumor evolution

A Ludwig Cancer Research study has discovered that the immune system's surveillance of cancer can itself induce metabolic adaptations in the cells of early-stage tumors that simultaneously promote their growth and equip them to suppress lethal immune responses.

5 Jan 2023

Does bimodal visual-olfactory training with patient-preferred scents improve olfaction in individuals with COVID-19 postviral olfactory loss?

Researchers investigated whether using patient-preferred scents and a bimodal method of visual-olfactory training is more effective than unimodal olfactory training using scents assigned by physicians in treating patients experiencing anosmia after COVID-19.

5 Jan 2023

SynGAP Research Fund awards $180,000 grant to the University of Edinburgh Medical School's Patrick Wild Centre & Centre for Discovery Brain Sciences

SynGAP Research Fund (SRF), a 501(c)(3) public charity whose mission is to improve the quality of life for SYNGAP1 patients through the research and development of treatments, therapies and support systems, along with SynGAP Research Fund UK, today announced they have awarded a $180,000 grant to the University of Edinburgh Medical School's Patrick Wild Centre & Centre for Discovery Brain Sciences to advance the science around gene transfer to correct SYNGAP1 haploinsufficiency.

5 Jan 2023

Study shows angiotensin-converting enzyme 2 decoy protein as a promising anti-SARS-CoV-2 agent

Researchers presented a microbody recombinant decoy protein with high affinity to angiotensin-converting enzyme 2 (ACE2) as an option for coronavirus disease 2019 (COVID-19) treatment.

5 Jan 2023

How effective is the bivalent mRNA SARS-CoV-2 vaccine in preventing COVID-19 hospitalizations and deaths?

Researchers examined the effectiveness of the bivalent mRNA vaccine against severe outcomes of COVID-19.

5 Jan 2023

Acupuncture could be a safe and feasible management option for IBS-D

Researchers preliminarily evaluated the practicality of utilizing the United States (US) Food and Drug Administration (FDA)-advocated endpoints to assess the effectiveness of acupuncture in IBS-D (irritable bowel syndrome with diarrhea) management.

5 Jan 2023

Study demonstrates safety and efficacy of a three-dose whole-parasite vaccine against malaria

A three-dose regimen of a whole-parasite vaccine against malaria – called Plasmodium falciparum sporozoite (PfSPZ) vaccine – demonstrated safety and efficacy when tested in adults living in Burkina Faso, West Africa, which has endemic malaria.

4 Jan 2023

Research offers a cost-effectiveness analysis of anticoagulant drugs for cancer-associated thrombosis

Newly published research out of the University of Cincinnati and the University of California-Davis shows that direct oral anticoagulant (DOAC) drugs are more effective and are more cost-effective than low molecular weight heparin for treating cancer-associated thrombosis.

4 Jan 2023

Is platelet-rich plasma therapy beneficial in treating chronic respiratory disease?

Researchers conducted a literature review to determine whether platelet-rich plasma therapy could help slow disease progression through lung regeneration in patients with chronic respiratory disease.

4 Jan 2023

Technical advances expand the application of mass spectrometry imaging in pharmaceutical research

Announcing a new publication for Acta Materia Medica journal. Mass spectrometry imaging (MSI) has been shown to be a valuable tool through nearly every stage of the preclinical drug research and development (R&D) pipeline, and even to the early phase of clinical pharmaceutical evaluation.

3 Jan 2023

Study compares effectiveness of Pfizer vs. Moderna booster COVID vaccines after third dose

In a recent scientific paper published in the journal Nature Microbiology, researchers reproduced two target trials using electronic health records (EHRs) of the Department of Veterans Affairs (VA) to compare the effectiveness of the third dose of BNT162b2 or messenger ribonucleic acid (mRNA)-1273 vaccine among United States (US) veterans.

3 Jan 2023

Benefits, challenges in the use of transcatheter pulmonary valve replacement for congenital heart disorders

Patients with congenital heart diseases often suffer from obstructions in the right ventricular outflow tract (RVOT), which carries blood from the heart to the lungs. These obstructions can be repaired with surgical procedures.

3 Jan 2023

Longitudinal seroprevalence study among pregnant people indicates waning of immunity from natural SARS-CoV-2 infections

Researchers evaluated the seroprevalence and durability of antibodies against SARS-CoV-2 nucleocapsid protein among pregnant individuals and investigated transplacental antibody transfer.

3 Jan 2023

Phase III trial shows noninferiority of VV116 compared to nirmatrelvir–ritonavir among adults with mild-to-moderate COVID-19 at risk of progression

Researchers presented the results of a phase III randomized controlled trial of oral SARS-CoV-2 antiviral VV116.

3 Jan 2023

Study suggests a single dose of JYNNEOS vaccine may lessen the severity of mpox illness

Researchers pursued evidence that the JYNNEOS vaccine offered some protection against the mpox disease, especially they confirmed the duration for which the one dose of this vaccine conferred protection.

3 Jan 2023

KAIST's neuroscientist announces recent advancements toward finding a cure for dystonia

KAIST's neuroscientist and professor, Dr. Daesoo Kim attended the "Conference for Musicians with Dystonia" supported by the World Health Organization (WHO) and the Carnegie Hall concert of legendary pianist João Carlos Martins, who is also a dystonia patient, to announce his team's recent advancements toward finding a cure for dystonia.

1 Jan 2023

Scientists explore efficacy of small molecule drugs against severe COVID-19 in vitro

Researchers evaluated the efficacy of small molecule drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro.

29 Dec 2022

Study reveals a previously unappreciated complexity of TRM cell biology in the gut

Recent pressure to maximize vaccine efficacy has stirred up many new discoveries within immunology, revealing numerous paradigms with untapped therapeutic potential.

28 Dec 2022

Efficacy News and Research

Researchers show how liver cancer cells hijack circadian clock machinery to divide and spread

Brief tele-cognitive behavioral therapy for head and neck cancer survivors with body-image distress shows promising results

Study details the “immunometabolic editing” mechanism of tumor evolution

Does bimodal visual-olfactory training with patient-preferred scents improve olfaction in individuals with COVID-19 postviral olfactory loss?

SynGAP Research Fund awards $180,000 grant to the University of Edinburgh Medical School's Patrick Wild Centre & Centre for Discovery Brain Sciences

Study shows angiotensin-converting enzyme 2 decoy protein as a promising anti-SARS-CoV-2 agent

How effective is the bivalent mRNA SARS-CoV-2 vaccine in preventing COVID-19 hospitalizations and deaths?

Acupuncture could be a safe and feasible management option for IBS-D

Study demonstrates safety and efficacy of a three-dose whole-parasite vaccine against malaria

Research offers a cost-effectiveness analysis of anticoagulant drugs for cancer-associated thrombosis

Is platelet-rich plasma therapy beneficial in treating chronic respiratory disease?

Technical advances expand the application of mass spectrometry imaging in pharmaceutical research

Study compares effectiveness of Pfizer vs. Moderna booster COVID vaccines after third dose

Benefits, challenges in the use of transcatheter pulmonary valve replacement for congenital heart disorders

Longitudinal seroprevalence study among pregnant people indicates waning of immunity from natural SARS-CoV-2 infections

Phase III trial shows noninferiority of VV116 compared to nirmatrelvir–ritonavir among adults with mild-to-moderate COVID-19 at risk of progression

Study suggests a single dose of JYNNEOS vaccine may lessen the severity of mpox illness

KAIST's neuroscientist announces recent advancements toward finding a cure for dystonia

Scientists explore efficacy of small molecule drugs against severe COVID-19 in vitro

Study reveals a previously unappreciated complexity of TRM cell biology in the gut

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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