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Scientists recreate initial steps of HIV infection in a test tube

Accomplishing a feat that had been a pipe dream for decades, scientists have recreated in a test tube the first steps of infection by HIV (human immunodeficiency virus), the virus that causes AIDS (acquired immunodeficiency syndrome).

9 Oct 2020

Higher HMBGB1 levels associated with obesity, inflammation, and cardiovascular disease in younger black adults

A "danger molecule" is higher in the blood of younger black adults than whites, females than males and increases with weight and age, researchers report in the first large, longitudinal study associating circulating HMGB1 levels with obesity, inflammation promoters and early indicators of cardiovascular risk in humans.

9 Oct 2020

FDA awards six clinical trial research grants to enhance development of therapies for rare diseases

Today, the U.S. Food and Drug Administration announced that it has awarded six new clinical trial research grants to principal investigators from academia and industry totaling over $16 million over the next four years.

8 Oct 2020

Researchers identify a promising method to stop COVID-19 infection

While the world waits eagerly for a safe and effective vaccine to prevent infections from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus behind the COVID-19 pandemic, researchers also are focusing on better understanding how SARS-CoV-2 attacks the body in the search for other means of stopping its devastating impact.

8 Oct 2020

Troublesome cough can be treated without disrupting the protective cough, shows study

Researchers might be able to treat a troublesome cough in disease without disrupting the protective cough we need for optimal lung health, by targeting the different brain circuits involved. That's according to new research published this week in The Journal of Physiology.

8 Oct 2020

Rapid, low-cost test for potential universal COVID-19 monitoring

An international team of researchers has presented a convenient, low-cost serology test to detect antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could potentially be made available universally.

7 Oct 2020

New biomarker may help identify patients at risk for graft-versus-host disease after stem cell transplants

A recent report published in Science Translational Medicine by MUSC Hollings Cancer Center investigator Sophie Paczesny, M.D., Ph.D., sheds light on immune cell biomarkers that may reveal which patients are most at risk for graft-versus-host disease (GVHD), a life-threatening condition that can arise after hematopoietic stem cell transplantation (HSCT) for treatment of liquid cancers such as leukemia.

7 Oct 2020

New imaging technique can replace invasive tissue biopsies in cancer treatment

Imaging techniques could replace the need for invasive tissue biopsies in helping rapidly determine whether cancer treatments are working effectively, according to researchers at the University of Cambridge.

7 Oct 2020

Researchers have discovered a safe, non-invasive way to manage blood sugar

Researchers from the University of Iowa may have discovered a safe new way to manage blood sugar non-invasively. Exposing diabetic mice to a combination of static electric and magnetic fields for a few hours per day normalizes two major hallmarks of type 2 diabetes, according to new findings published Oct. 6 in Cell Metabolism.

7 Oct 2020

Genetic risk scoring of lipoprotein(a) can predict risk of atherosclerotic cardiovascular disease

Elevated levels of a little-known lipoprotein in the blood that may put people at high risk of cardiovascular disease can be as accurately detected by genetic testing as by conventional laboratory measurement, researchers at Massachusetts General Hospital (MGH) have found.

6 Oct 2020

Study finds high out-of-pocket spending on orphan drugs for rare childhood diseases

Only about one in every 170 children take them. But "orphan drugs" accounted for 1 in every 15 private insurance dollars spent on children's health care in the United States in 2018, according to a new study. That's up 65% from just five years before.

6 Oct 2020

Study shows how amino acids are transported across liposome and cell membranes

The transport of amino acids and other molecules across the cell's membrane plays a crucial role in the metabolism of cells and, therefore, in human health.

6 Oct 2020

Higher vitamin D levels in pregnancy may protect children from developing high blood pressure

Children appear to be at greater risk of having high blood pressure when their mothers had the high blood pressure condition called preeclampsia during pregnancy--but this adverse association may be reduced or even eliminated for children who were exposed to higher levels of vitamin D in the womb, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

6 Oct 2020

Researchers discover a new, rapid method to fabricate nanoparticles

Northwestern University researchers are casting a net for nanoparticles.The team has discovered a new, rapid method for fabricating nanoparticles from a simple, self-assembling polymer.

6 Oct 2020

Chronic illnesses promote active SARS-CoV-2 infection via suppressed mucosal immunity

A recent paper published in the preprint server medRxiv in September 2020 discusses the “clinically relevant variation in the expression of COVID-19-related genes”, which is associated with the host and environmental factors, as well as host genetic factors.

6 Oct 2020

Advanced model reveals dynamic motions of SARS-COV-2 spike-shielding glycans

A recent paper published on the preprint server bioRxiv in September 2020 discusses the dynamic interactions of the spike protein glycan shield, which may be of great value in developing therapeutic compounds to fight severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

5 Oct 2020

Understanding how the malaria parasite can withstand fever's heat

Even when a person suffering from malaria is burning up with fever and too sick to function, the tiny blood-eating parasites lurking inside them continue to flourish, relentlessly growing and multiplying as they gobble up the host's red blood cells.

5 Oct 2020

Wyss Institute’s technologies licensed to Agile Biodetection to aid COVID-19 diagnostic efforts

The Wyss Institute for Biologically Inspired Engineering at Harvard University announced today that its nasopharyngeal swab and toehold switch technologies have been licensed to Alabama-based Agile Biodetection, which will use them to develop solutions for unmet diagnostic needs in the detection of the SARS-CoV-2 virus in environmental or clinical settings.

5 Oct 2020

Scientists discover small molecules that may reduce cellular stress

For many, getting older can unfortunately mean an increased risk of illness from cardiovascular disease to cancer.

5 Oct 2020

New approach transforms oldest antibiotics into safer, stronger drugs

Physicians and scientists have long searched the natural world for chemicals that can improve human health. However, evolutionary selection optimized natural chemicals to benefit their host, not for safety or efficacy in humans.

5 Oct 2020

Molecule News and Research

Scientists recreate initial steps of HIV infection in a test tube

Higher HMBGB1 levels associated with obesity, inflammation, and cardiovascular disease in younger black adults

FDA awards six clinical trial research grants to enhance development of therapies for rare diseases

Researchers identify a promising method to stop COVID-19 infection

Troublesome cough can be treated without disrupting the protective cough, shows study

Rapid, low-cost test for potential universal COVID-19 monitoring

New biomarker may help identify patients at risk for graft-versus-host disease after stem cell transplants

New imaging technique can replace invasive tissue biopsies in cancer treatment

Researchers have discovered a safe, non-invasive way to manage blood sugar

Genetic risk scoring of lipoprotein(a) can predict risk of atherosclerotic cardiovascular disease

Study finds high out-of-pocket spending on orphan drugs for rare childhood diseases

Study shows how amino acids are transported across liposome and cell membranes

Higher vitamin D levels in pregnancy may protect children from developing high blood pressure

Researchers discover a new, rapid method to fabricate nanoparticles

Chronic illnesses promote active SARS-CoV-2 infection via suppressed mucosal immunity

Advanced model reveals dynamic motions of SARS-COV-2 spike-shielding glycans

Understanding how the malaria parasite can withstand fever's heat

Wyss Institute’s technologies licensed to Agile Biodetection to aid COVID-19 diagnostic efforts

Scientists discover small molecules that may reduce cellular stress

New approach transforms oldest antibiotics into safer, stronger drugs

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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