Respiratory News and Research

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Small molecule inhibitor found to be effective against SARS-CoV-2 variants

In a new study, researchers developed RK-33, a small molecule inhibitor of DDX3, and evaluated its efficacy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs).

12 Sep 2022

BNT162b2 SARS-CoV-2 vaccinations found to reduce incidence of long COVID symptoms

Researchers assessed the association between Pfizer-BioNTech’s SARS-CoV-2 BNT162b2 messenger ribonucleic acid (mRNA) vaccination and the incidence of post-COVID-19 symptoms among Israeli adults.

12 Sep 2022

What is the impact of COVID-19 vaccination on erectile function?

A recent study reported that COVID-19 vaccination does not elevate the risk of erectile dysfunction.

12 Sep 2022

Dissecting vaccinia virus and monkeypox virus-specific T cell responses in humans

In a new study, a team of researchers studied different antigens targeted by vaccinia virus (VACV)- and monkeypox virus (MPXV)-specific T cells.

12 Sep 2022

The long-term clinical status of pediatric patients after testing positive for COVID-19

A recent study found that the most common long COVID symptoms in the pediatric population showed a higher prevalence among patients in the age range of 6-17 years and were identical to those reported in adults.

12 Sep 2022

SARS-CoV-2 Omicron BA.4.6 resistant to many therapeutic monoclonal antibodies in clinical use

In a recent study posted to the bioRxiv* preprint server, researchers in Taiwan and the United States explore the resistance of a newly emergent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sub-variant BA.4.6 to the therapeutic monoclonal antibodies currently being used to treat coronavirus disease 2019 (COVID-19).

12 Sep 2022

Interferon response induced by Omicron BA.1 and BA.5 prevents influenza A infection

In a recent study posted to the bioRxiv* preprint server, researchers in Germany and the United Kingdom investigated the interferon responses induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant and SARS-CoV-2 Omicron sub-variants BA.1 and BA.5, and their efficacy in protecting cells from influenza A virus super-infection.

12 Sep 2022

Self-replicating intradermal RNA vaccine against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers assessed the efficiency of a controllable self-replicating ribonucleic acid (c-srRNA) vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

12 Sep 2022

Pre-existing psychological distress increases risk of long-COVID

In a recent study published in the Journal of American Medical Association (JAMA) Psychiatry, researchers investigated the association of psychological distress before coronavirus disease 2019 (COVID-19) with the risk of post-acute sequelae of COVID-19 (PASC).

12 Sep 2022

Pollutant particles in the air trigger lung cancer in non-smokers

A new mechanism has been identified through which very small pollutant particles in the air may trigger lung cancer in people who have never smoked, paving the way to new prevention approaches and development of therapies, according to late-breaking data [to be] reported at the ESMO Congress 2022 by scientists of the Francis Crick Institute and University College London, funded by Cancer Research UK. The particles, which are typically found in vehicle exhaust and smoke from fossil fuels, are associated with non-small cell lung cancer (NSCLC) risk, accounting for over 250,000 lung cancer deaths globally per year.

12 Sep 2022

Brain injury a common consequence of both COVID-19 and influenza

In a recent study published in the journal Brain, researchers reported that brain injury is common in coronavirus disease 2019 (COVID-19) and influenza.

12 Sep 2022

Antibody escape less pronounced with BA.2.75 compared to BA.4/5

In a recent study published in the Lancet, researchers evaluated the antibody neutralization sensitivity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.2.75 subvariant.

11 Sep 2022

Discovery of antibodies that may eliminate the need for COVID vaccines

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11 Sep 2022

Climate change has increased the risk of bat-borne pathogen spillover

In a recent study posted to the bioRxiv* preprint server, researchers retrospectively assessed the association between climate change and disease spillover risks triggered by bat distribution changes based on historical climate and vampire-bat occurrence data for the previous century (1900-2020).

11 Sep 2022