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Researchers find direct link between MCL1 protein and cell-cycle checkpoint protein

Human cells respond to stresses like DNA damage, metabolic imbalance and starvation by first trying to repair the problem.

5 Apr 2020

Researchers uncover mechanism by which gene mutations potentially give rise to kidney disease

Researchers from the Center for Precision Disease Modeling at the University of Maryland School of Medicine have uncovered a mechanism that appears to explain how certain genetic mutations give rise to a rare genetic kidney disorder called nephrotic syndrome.

5 Apr 2020

First genome sequences of SARS-CoV-2 viruses in Austria openly available

The first 21 SARS-CoV-2 genomes in Austria have now been completed and published within the scope of the “Mutational Dynamics of SARS-CoV-2” project recently launched by CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, in close collaboration with the Medical University of Vienna.

3 Apr 2020

Investigating Human Disease with Mass Spectrometry-based Proteomics

Dr. Andrew Webb describes how his lab uses mass spectrometry-based techniques to understand the role of post-translational modifications in human disease.

From Bruker Daltonics 3 Apr 2020

Starving pancreatic cancer cells of cysteine may induce tumor ferroptosis

A new study from Columbia University Irving Medical Center and the Herbert Irving Comprehensive Cancer Center suggests a compound in development for a rare kidney stone disease may have potential against pancreatic cancer.

2 Apr 2020

New study offers clues to why autism is more common in boys than in girls

A new study in Neuron offers clues to why autism spectrum disorder is more common in boys than in girls. National Institutes of Health scientists found that a single amino acid change in the NLGN4 gene, which has been linked to autism symptoms, may drive this difference in some cases.

2 Apr 2020

Measuring the severity of COVID-19 using a model-based analysis

Researchers have modeled the progression and severity of COVID-19. Their study titled “Estimates of the severity of coronavirus disease 2019: a model-based analysis” was published in the latest issue of The Lancet Infectious Diseases.

1 Apr 2020

Location of broken bone in older people can have major impact on long-term health outcomes

In older individuals, the location of a broken bone can have significant impacts on long-term health outcomes, according to research accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society.

31 Mar 2020

Novel immunotherapy eradicates solid tumors in mice without adverse side effects

Scientists have developed a new immunotherapy that eradicates solid tumors in mice without adverse side effects, according to a new study published today in eLife.

31 Mar 2020

NIH researchers identify a second gene that causes melorheostosis

Researchers at the National Institutes of Health have discovered a second gene that causes melorheostosis, a rare group of conditions involving an often painful and disfiguring overgrowth of bone tissue.

31 Mar 2020

New viable therapeutic strategy found for ER+ breast cancer

Researchers say they have found a viable new therapeutic strategy for estrogen receptor-positive (ER+) breast cancer, even cancers that are resistant to current standard of care treatments.

31 Mar 2020

Editorial challenges U.S. healthcare system to reconsider conventional care for diverticulitis

An editorial challenges physicians and the U.S. healthcare system to reconsider the current "one size fits all" care for diverticulitis and to employ a precision medicine approach to determine which patients should be referred for colonoscopy.

31 Mar 2020

First-of-its-kind trial identifies a viable target for treating anhedonia

A first-of-its-kind trial has demonstrated that a receptor involved in the brain's reward system may be a viable target for treating anhedonia (or lack of pleasure), a key symptom of several mood and anxiety disorders.

31 Mar 2020

Unraveling gut-to-brain communication paves way for targeted treatments

Scientists at Flinders University have, for the first time, identified a specific type of sensory nerve ending in the gut and how these may 'talk' to the spinal cord, communicating pain or discomfort to the brain.

30 Mar 2020

Zebrafish can provide genetic clues to human nicotine addiction

Researchers at Queen Mary University of London have shown that zebrafish can provide genetic clues to smoking, a complex human behavior.

30 Mar 2020

Scientists model human CMV-induced microcephaly using brain organoids

A City of Hope scientist is one step closer to discovering what weakens a pathogen that appears to cause babies to be born with abnormally small heads.

30 Mar 2020

Genetic mutation found to improve cognitive flexibility in mice

Researchers at the National Institutes of Health have discovered in mice what they believe is the first known genetic mutation to improve cognitive flexibility--the ability to adapt to changing situations.

27 Mar 2020

Fast-acting anti-malarial compound shows promise in first clinical trial

A fast-acting anti-malarial compound discovered at St. Jude Children's Research Hospital was well tolerated and showed promising anti-malarial effects in the first study in humans.

27 Mar 2020

Global scientific collaboration produces first genetic map of the cerebral cortex

The cerebral cortex is the relatively thin, folded, outer "gray matter" layer of the brain crucial for thinking, information processing, memory, and attention.

27 Mar 2020

New 'more effective' stem cell transplant method could improve treatment of blood diseases

Researchers at UCL have developed a new way to make blood stem cells present in the umbilical cord 'more transplantable', a finding in mice which could improve the treatment of a wide range of blood diseases in children and adults.

26 Mar 2020

Medical Research News and Research

Researchers find direct link between MCL1 protein and cell-cycle checkpoint protein

Researchers uncover mechanism by which gene mutations potentially give rise to kidney disease

First genome sequences of SARS-CoV-2 viruses in Austria openly available

Investigating Human Disease with Mass Spectrometry-based Proteomics

Starving pancreatic cancer cells of cysteine may induce tumor ferroptosis

New study offers clues to why autism is more common in boys than in girls

Measuring the severity of COVID-19 using a model-based analysis

Location of broken bone in older people can have major impact on long-term health outcomes

Novel immunotherapy eradicates solid tumors in mice without adverse side effects

NIH researchers identify a second gene that causes melorheostosis

New viable therapeutic strategy found for ER+ breast cancer

Editorial challenges U.S. healthcare system to reconsider conventional care for diverticulitis

First-of-its-kind trial identifies a viable target for treating anhedonia

Unraveling gut-to-brain communication paves way for targeted treatments

Zebrafish can provide genetic clues to human nicotine addiction

Scientists model human CMV-induced microcephaly using brain organoids

Genetic mutation found to improve cognitive flexibility in mice

Fast-acting anti-malarial compound shows promise in first clinical trial

Global scientific collaboration produces first genetic map of the cerebral cortex

New 'more effective' stem cell transplant method could improve treatment of blood diseases

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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