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Tau protein shows unexpected benefits in mitigating brain damage

A study by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, reveals that the protein Tau – a key player implicated in several neurodegenerative conditions including Alzheimer's disease – also plays a positive role in the brain.

30 Aug 2024

Clonal hematopoiesis identified as new risk factor for atherosclerosis

To the known risk factors for cardiovascular disease - high blood pressure, high cholesterol, diabetes, overweight and obesity, smoking, and physical inactivity - a new one has to be added: clonal hematopoiesis.

30 Aug 2024

UCLA team develops automated HER2 scoring system with deep learning and pyramid sampling

HER2 is a critical protein that plays a pivotal role in breast cancer cell growth and aggressiveness. Its expression level is a key indicator for treatment decisions, including the use of HER2-targeted therapies.

30 Aug 2024

EU-funded MASTER project develops first comprehensive database of food metagenomes

The first comprehensive database of food metagenomes has been developed by the EU-funded MASTER project.

30 Aug 2024

AI tool RENAISSANCE transforms creation of kinetic models in cellular metabolism

Understanding how cells process nutrients and produce energy - collectively known as metabolism - is essential in biology. However, analyzing the vast amounts of data on cellular processes to determine metabolic states is a complex task.

30 Aug 2024

Redefining 5hmC: More than just a stepping stone in the DNA demethylation pathway

An important DNA modification is methylation, or the addition of a methyl group to the 5th carbon of cytosine. This forms 5-methylcytosine (5mC), typically associated with repression of gene expression.

From biomodal 30 Aug 2024

Carcinotech publishes research on patient-derived 3D-printed tumors as a breakthrough tool for drug development

Advances in tissue engineering and 3D bioprinting have revolutionized the development of physiologically relevant 3D in vitro cancer models, offering a closer representation of the tumor microenvironment (TME) and enabling high-throughput drug screening.

From Carcinotech 30 Aug 2024

The Arctic Sea revealed as a potential treasure trove for new medicines

Researchers discovered new antivirulence and antibacterial compounds from Arctic marine actinobacteria, offering potential solutions to combat antibiotic-resistant E. coli infections.

30 Aug 2024

$Regulatory T cells play a key role in fracture healing and tissue repair$

Regulatory T cells play a key role in fracture healing and tissue repair

The study uncovers a unique reparative function of regulatory T cells (Tregs) in the process of fracture healing, a discovery that adds a new dimension to our understanding of the immune response in tissue regeneration.

29 Aug 2024

Fibrin fuels thromboinflammation and brain damage in COVID-19

Researchers reveal fibrin's critical role in COVID-19 by driving thromboinflammation and neuropathology, and highlight a potential antibody therapy to mitigate these effects.

29 Aug 2024

Discovery of borderzone inflammation offers new avenues for heart failure prevention

Ischemic heart disease is the most common cause of death in the world. It begins with a "heart attack", also known as a myocardial infarction (MI), which causes part of the heart to die due to inadequate coronary blood flow.

29 Aug 2024

New bacterial defense mechanism revealed as potential tool for genome editing

Scientists who have described in a new study the step-by-step details of a bacterial defense strategy see the mechanism as a promising platform for development of a new genome-editing method.

29 Aug 2024

Studies uncover mechanisms behind micronuclear instability and cancer progression

Reactive oxygen species (ROS) from mitochondria are key drivers of genetic chaos in cancer by causing the collapse of micronuclear envelopes, a process that fuels the chromosomal instability (CIN) often observed in aggressive tumor behavior.

29 Aug 2024

CD4 T cells found to be key players in tuberculosis defense

The body's first line of defense against tuberculosis (TB) involves immune cells that suppress lung inflammation instead of activating it, reported University of Pittsburgh and the Ragon Institute of Mass General, MIT, and Harvard scientists today in Immunity.

29 Aug 2024

Nucleic acids in food show potential to inhibit cancer cell growth

When people eat, they ingest the nucleic acids that reside in all living things. The compounds in these acids could inhibit the growth of cancer cells, according to findings published in PLOS ONE by Osaka Metropolitan University Associate Professor Akiko Kojima-Yuasa of the Graduate School of Human Life and Ecology and colleagues.

29 Aug 2024

Distinct waves of T cells generated by each dose of combination immunotherapy

A new tool for monitoring immune health patterns over time has revealed how a pair of checkpoint inhibitor therapies works together to recruit new cancer-fighting T cells with every infusion.

29 Aug 2024

Study reveals key role of A20 protein in controlling inflammation in liver disease

Many individuals worldwide suffer from chronic liver disease (CLD), which poses significant concerns for its tendency to lead to hepatocellular carcinoma or liver failure. CLD is characterized by inflammation and fibrosis.

29 Aug 2024

Mapping DNA’s hidden knot-like structures may revolutionize disease treatment

Innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer.

29 Aug 2024

Study explores link between prostate cancer treatment and Alzheimer’s disease

Researchers at the Medical College of Georgia at Augusta University are searching for a better way to understand why many men with prostate cancer end up with Alzheimer's disease, and whether it's the standard hormone therapy treatment or an overactive immune response that actually contributes to the problem.

29 Aug 2024

Researchers uncover magnesium’s crucial role in cellular energy production

An international research team led by Umeå professor Magnus Wolf-Watz has discovered how the magnesium atom directs the chemistry that catalyzes the production of the energy molecule ATP in a cell. ATP is a vital driving force in the cell.

29 Aug 2024

B Cell News and Research

Tau protein shows unexpected benefits in mitigating brain damage

Clonal hematopoiesis identified as new risk factor for atherosclerosis

UCLA team develops automated HER2 scoring system with deep learning and pyramid sampling

EU-funded MASTER project develops first comprehensive database of food metagenomes

AI tool RENAISSANCE transforms creation of kinetic models in cellular metabolism

Redefining 5hmC: More than just a stepping stone in the DNA demethylation pathway

Carcinotech publishes research on patient-derived 3D-printed tumors as a breakthrough tool for drug development

The Arctic Sea revealed as a potential treasure trove for new medicines

Regulatory T cells play a key role in fracture healing and tissue repair

Fibrin fuels thromboinflammation and brain damage in COVID-19

Discovery of borderzone inflammation offers new avenues for heart failure prevention

New bacterial defense mechanism revealed as potential tool for genome editing

Studies uncover mechanisms behind micronuclear instability and cancer progression

CD4 T cells found to be key players in tuberculosis defense

Nucleic acids in food show potential to inhibit cancer cell growth

Distinct waves of T cells generated by each dose of combination immunotherapy

Study reveals key role of A20 protein in controlling inflammation in liver disease

Mapping DNA’s hidden knot-like structures may revolutionize disease treatment

Study explores link between prostate cancer treatment and Alzheimer’s disease

Researchers uncover magnesium’s crucial role in cellular energy production

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