Clinical Trial News and Research

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Antibody drug improves survival rates in canine prostate cancer model

Dogs are proving to be a far better scientific model for study of prostate cancer than mice, the typical animal used in the lab for this type of research.

8 Feb 2022

Study assesses the effectiveness of e-cigarettes as a smoking cessation aid

Using e-cigarettes to stop smoking may result in fewer successful quit attempts than trying to quit using other smoking cessation aids, such as nicotine replacement therapy (NRT) or meds, suggests US research published online in the journal Tobacco Control.

8 Feb 2022

Reanalysis of the efficacy of COVID-19 vaccines

In a new study, researchers investigated the impact of trial study design and other parameters on the estimates of COVID-19 vaccine efficacy.

8 Feb 2022

Paracetamol use increases blood pressure, study shows

Long-term paracetamol use could increase the risk of heart disease and strokes in people with high blood pressure, a study suggests.

7 Feb 2022

Digital assistants can help older adults with dementia remember daily tasks

Older adults with dementia or mild cognitive impairment sometimes struggle to remember daily tasks, including managing medications, shopping for groceries and tracking upcoming events, including birthdays, anniversaries or doctor appointments.

7 Feb 2022

$Spinal anesthesia not superior to general anesthesia for hip-fracture surgery in older adults$

Spinal anesthesia not superior to general anesthesia for hip-fracture surgery in older adults

Spinal anesthesia is not safer or more effective than general anesthesia in patients who undergo surgery for hip fractures, according to a major study.

7 Feb 2022

Two peanut allergy treatments for children found to be highly effective at inducing remission

Researchers have discovered two peanut allergy treatments for children that are both highly effective at inducing remission.

7 Feb 2022

Colchicine holds promise to reduce the risk of severe COVID-19

A recent article, published in Rheumatology and Therapy, reviews the potent evidence of colchicine against the SARS-CoV-2 infection.

7 Feb 2022

Switching from metered-dose inhaler to a dry powder reduces carbon footprint of asthma treatment

Switching from a metered-dose inhaler to a dry powder version for maintenance therapy more than halves the carbon footprint of people with asthma, and without any worsening of their condition, finds a pharma industry sponsored study published online in the journal Thorax.

6 Feb 2022

Drug used to treat skin and lung cancers slows the progression of ovarian cancer sub-type

A drug currently used to treat skin and lung cancers has been found to slow the progression of a form of ovarian cancer and increase the number of patients who respond to treatment, a clinical trial has found.

4 Feb 2022

Gene therapy may be a curative treatment option for patients with transfusion-dependent beta-thalassemia

A novel gene therapy promoted transfusion independence in more than 90 percent of adult and pediatric patients with transfusion-dependent beta-thalassemia, according to a recent clinical trial published in The New England Journal of Medicine.

3 Feb 2022

Ketamine is rapid, safe, and effective in treating hospitalized suicidal patients

Ketamine is a fast acting, efficient treatment for patients hospitalized for severe suicidal thoughts (ideation), finds a clinical trial published by The BMJ today.

3 Feb 2022

Booster dose of Covaxin vaccine candidate neutralizes Omicron and Delta variants

Researchers evaluate the neutralization potential of sera samples from subjects boosted with the Covaxin against the SARS-CoV-2 Omicron variant.

2 Feb 2022

UCLA researchers develop first human genomic transgenic mouse model of Huntington's disease

Researchers at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA and the David Geffen School of Medicine at UCLA have developed a new mouse model of Huntington's disease that recapitulates more Huntington's disease-like characteristics than earlier models.

2 Feb 2022

Study finds abnormal link between autonomic and central nervous systems in patients with generalized anxiety disorder

Researchers at the Laureate Institute for Brain Research (LIBR) in Tulsa, Okla., have identified an abnormal link between the autonomic and central nervous systems, specifically via communication between the heart and part of the brain's frontal cortex, in women with generalized anxiety disorder (GAD).

2 Feb 2022

Assessing an intranasal lentiviral booster against COVID-19 variants

A new study explores the possibility of vaccination via nasal route utilizing a lentiviral vaccination vector (LV) to be administered as a booster dose against COVID-19.

2 Feb 2022

New approach to CAR T-cell therapy for B-cell cancers triples the targeted antigens on cancer cells

Researchers at University Hospitals Seidman Cancer Center and Case Western Reserve University have developed a novel approach to chimeric antigen receptor (CAR) T-cell therapy for B-cell cancers that triples the targeted antigens on cancer cells – a "back up" approach that promises to greatly reduce the potential for antigen escape currently found in CAR T therapies that solely target CD19.

2 Feb 2022

Experimental immunotherapy could help treat some people with metastatic breast cancer

An experimental form of immunotherapy that uses an individual's own tumor-fighting immune cells could potentially be used to treat people with metastatic breast cancer, according to results from an ongoing clinical trial led by researchers at the National Cancer Institute's Center for Cancer Research, part of the National Institutes of Health.

1 Feb 2022

Pictorial warnings could be a promising option to reduce purchases of sugary drinks for children

Purchases of sugary drinks could be reduced by pictorial health warnings, reports research publishing February 1st in the open access journal PLOS Medicine.

1 Feb 2022

Study suggests an etiological link between obesity and female reproductive disorders

Obesity is associated with an increased risk of developing female reproductive disorders, however, the roles and mechanisms of obesity in the cause(s) of reproductive conditions are unclear.

1 Feb 2022

Clinical Trial News and Research

Antibody drug improves survival rates in canine prostate cancer model

Study assesses the effectiveness of e-cigarettes as a smoking cessation aid

Reanalysis of the efficacy of COVID-19 vaccines

Paracetamol use increases blood pressure, study shows

Digital assistants can help older adults with dementia remember daily tasks

Spinal anesthesia not superior to general anesthesia for hip-fracture surgery in older adults

Two peanut allergy treatments for children found to be highly effective at inducing remission

Colchicine holds promise to reduce the risk of severe COVID-19

Switching from metered-dose inhaler to a dry powder reduces carbon footprint of asthma treatment

Drug used to treat skin and lung cancers slows the progression of ovarian cancer sub-type

Gene therapy may be a curative treatment option for patients with transfusion-dependent beta-thalassemia

Ketamine is rapid, safe, and effective in treating hospitalized suicidal patients

Booster dose of Covaxin vaccine candidate neutralizes Omicron and Delta variants

UCLA researchers develop first human genomic transgenic mouse model of Huntington's disease

Study finds abnormal link between autonomic and central nervous systems in patients with generalized anxiety disorder

Assessing an intranasal lentiviral booster against COVID-19 variants

New approach to CAR T-cell therapy for B-cell cancers triples the targeted antigens on cancer cells

Experimental immunotherapy could help treat some people with metastatic breast cancer

Pictorial warnings could be a promising option to reduce purchases of sugary drinks for children

Study suggests an etiological link between obesity and female reproductive disorders

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