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Study detects key differences in immune responses of adults and children with COVID-19

The first study comparing the immune responses of adults and children with COVID-19 has detected key differences that may contribute to understanding why children usually have milder disease than adults.

22 Sep 2020

Strength, duration of immunity will shape the future trajectory of COVID-19

New research suggests that the impact of natural and vaccine-induced immunity will be key factors in shaping the future trajectory of the global coronavirus pandemic, known as COVID-19.

21 Sep 2020

Research underlines SARS-CoV-2 N-terminal domain of Nsp1 as a potential drug target

A recent study reveals how the non-structural protein 1 (NSP1) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays a crucial role in inhibiting the host cell protein synthesis but simultaneously facilitating the viral protein synthesis.

21 Sep 2020

Study finds how different strategies may impact clinical trial enrollment

As electronic medical records (EMR) become ubiquitous in health care settings, scientists are increasingly turning to electronic-based recruitment methods to encourage participation in clinical trials.

21 Sep 2020

New $6.2 million study seeks to define molecular linkages between aging and Parkinson's

A collaborative team between the University of Minnesota Medical School and Van Andel Institute will soon begin a $6.2 million study that seeks to define the molecular linkages between aging and Parkinson's disease -- an approach for new treatment targets not yet explored by many researchers.

21 Sep 2020

New discovery of an interaction between sensory neurons and immune cells

Pain is a protective mechanism, alerting us to danger by generating an unpleasant sensation. The warning message is carried to the spinal cord by specialized sensory neurons, which are intertwined with other sensory and motor neurons in peripheral nerves.

21 Sep 2020

Research uncovers potential cause of neurotoxicity due to immunotherapy

New research has uncovered the previously unknown presence of CD19 -- a B cell molecule targeted by chimeric antigen receptor (CAR) T cell immunotherapy to treat leukemia, lymphoma, and multiple myeloma -- in brain cells that protect the blood brain barrier (BBB).

21 Sep 2020

Trial shows new first-line treatment option for patients with metastatic kidney cancer

The results of the phase 3 CheckMate 9ER trial have provided a new first-line treatment option for patients with metastatic kidney cancer. The late breaking results are presented at ESMO 2020.

19 Sep 2020

Gene therapy used to overcome the cardiac effects of Freidreich’s ataxia

Gene therapy was successfully used to overcome the cardiac effects of Freidreich’s ataxia (FA) in a mouse model of the disease, as reported in the peer-reviewed journal Human Gene Therapy. Click here to read the full-text article free online through October 18, 2020.

19 Sep 2020

Enhancing the efficacy of anti-PD-L1 immunotherapy for cancer

For most people, there is no scarier diagnosis than that of cancer. While treatments including chemotherapy and radiotherapy have been used since the 1940s and late 1800s, respectively, immunotherapy has more recently emerged as a viable and successful approach to cancer treatment.

18 Sep 2020

Cellular recyclers could be used to eliminate the driver of cancer's aggressiveness

"Do not erase." "Recycle me." "Free to a good home." Humans post these signs to indicate whether something has value or not, whether it should be disposed of or not.

18 Sep 2020

Molecular imaging probe reveals Alzheimer's-related γ-secretase in rodents, macaques

Scientists at the Massachusetts General Hospital (MGH) have developed a molecular imaging probe to reveal Alzheimer's disease (AD)-related γ-secretase in rodents and macaques with translational potentials in humans.

18 Sep 2020

MDI Biological Laboratory receives €280,000 to address the problem of tendon injury

Modern medicine has made tremendous strides in replacing organs and hips. But what about those all-important tendons, which enable joint movement by connecting muscle to bone? Tendon injuries, such as those in the knee, elbow, Achilles tendon and rotator cuff (shoulder) exact a huge cost in terms of health care, productivity and quality of life.

17 Sep 2020

Novel mechanism that may confer protection against glaucoma identified

A team of researchers from LSU Health New Orleans Neuroscience Center of Excellence and the University of Copenhagen provides the first evidence that patients with ocular hypertension may exhibit superior antioxidant protection that promotes resistance to the elevated intraocular pressure associated with glaucoma.

17 Sep 2020

IU School of Medicine wins $12.3 million grant for research into opioid addiction treatment

Researchers at Indiana University School of Medicine are testing use of tezampanel, a novel antagonist at glutamate receptors that could treat opioid withdrawal syndrome and other addictions and mental illnesses.

17 Sep 2020

Study finds increased risk of serious complications in children taking oral steroids

Children who take oral steroids to treat asthma or autoimmune diseases have an increased risk of diabetes, high blood pressure, and blood clots, according to Rutgers researchers.

17 Sep 2020

Entrepreneurs to present their healthcare innovations in virtual event

Both events will be held online; free registration and information is available at http://bit.ly/M2D2 Challenge Events.

17 Sep 2020

Children who experience neglect are more likely to have teen pregnancy

Children who experience neglect are seven times more likely than other abuse victims to have a teen pregnancy say University of Queensland researchers.

17 Sep 2020

Study shows how the body's immune system finds intruding or damaged cells

Research led by Dr. Wonmuk Hwang has led to better understanding on how components of the body's immune system find intruding or damaged cells, which could lead to novel approaches to viral and cancer treatments.

17 Sep 2020

Non-invasive test of brain function could predict treatment response in depressed teen girls

The risk of developing major depressive disorder (MDD) surges during adolescence-particularly for girls. Cognitive behavioral therapy (CBT) can be an effective treatment, but only about half of girls diagnosed with depression show significant improvement.

16 Sep 2020

Medical School News and Research

Study detects key differences in immune responses of adults and children with COVID-19

Strength, duration of immunity will shape the future trajectory of COVID-19

Research underlines SARS-CoV-2 N-terminal domain of Nsp1 as a potential drug target

Study finds how different strategies may impact clinical trial enrollment

New $6.2 million study seeks to define molecular linkages between aging and Parkinson's

New discovery of an interaction between sensory neurons and immune cells

Research uncovers potential cause of neurotoxicity due to immunotherapy

Trial shows new first-line treatment option for patients with metastatic kidney cancer

Gene therapy used to overcome the cardiac effects of Freidreich’s ataxia

Enhancing the efficacy of anti-PD-L1 immunotherapy for cancer

Cellular recyclers could be used to eliminate the driver of cancer's aggressiveness

Molecular imaging probe reveals Alzheimer's-related γ-secretase in rodents, macaques

MDI Biological Laboratory receives €280,000 to address the problem of tendon injury

Novel mechanism that may confer protection against glaucoma identified

IU School of Medicine wins $12.3 million grant for research into opioid addiction treatment

Study finds increased risk of serious complications in children taking oral steroids

Entrepreneurs to present their healthcare innovations in virtual event

Children who experience neglect are more likely to have teen pregnancy

Study shows how the body's immune system finds intruding or damaged cells

Non-invasive test of brain function could predict treatment response in depressed teen girls

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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