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Millennium Laboratories announces new clinical quantitative assay and drug screening tests for healthcare

Millennium Laboratories, a leading provider of therapeutic drug monitoring and education to physicians and staff treating chronic pain patients, announced today the company’s development and validation of a clinical quantitative assay for the new drug tapentadol (Nucynta™) by liquid chromatography/tandem mass spectrometry (LC-MS/MS).

12 Nov 2009

Stapled Peptides can inhibit key intracellular biological targets, says new research

Aileron Therapeutics, a biopharmaceutical company leading the development of a new class of drugs called Stapled Peptides, announced today that its collaborators, James E. Bradner, MD of the Dana-Farber Cancer Institute and the Broad Institute of Harvard and MIT, and Gregory L. Verdine, PhD, Professor of Chemistry at Harvard University, published research in Nature entitled, "Direct Inhibition of the Notch Transcription Factor Complex." Results presented in the paper showed that Stapled Peptides can potently and directly inhibit the transcription factor Notch, an oncogene implicated in cancer cell proliferation and survival.

12 Nov 2009

Novel breakthrough may lead to new methods for sterilizing food and medical equipment

Got food poisoning? The cause might be bacterial spores, en extremely hardy survival form of bacteria, a nightmare for health care and the food industry and an enigma for scientists. Spore-forming bacteria, present almost everywhere in our environment, can also cause serious infectious diseases, such as tetanus, anthrax, and botulism.

12 Nov 2009

Scientists report largest-ever collection of data about the proteins produced by genes in a single human organ

Scientists at a group of 11 research centers in China are reporting for the first time assembly of the largest-ever collection of data about the proteins produced by genes in a single human organ. Their focus was the liver, and their massive database in both protein and transcript levels could become a roadmap for finding possible new biomarkers and treatments for liver disease.

12 Nov 2009

IMS Health to launch comprehensive analytical tool for oncology market

IMS Health, the world’s leading provider of market intelligence to the pharmaceutical and healthcare industries, today announced the upcoming launch of IMS Oncology QuantifierTM, a comprehensive, clinically rich analytical tool that enables the company’s clients to assess treatment opportunities and guide commercial decisions in the $48 billion global oncology market.

12 Nov 2009

Scientists find way to disarm "undruggable" protein; discovery lays foundation for new kind of cancer therapy

Scientists have devised an innovative way to disarm a key protein considered to be "undruggable," meaning that all previous efforts to develop a drug against it have failed. Their discovery, published in the November 12 issue of Nature, lays the foundation for a new kind of therapy aimed directly at a critical human protein — one of a few thousand so-called transcription factors — that could someday be used to treat a variety of diseases, especially multiple types of cancer.

12 Nov 2009

Researchers identify a new mechanism that inhibits the formation of new blood vessels

Researchers at Uppsala University, in collaboration with colleagues in Sweden and abroad, have identified an entirely new mechanism by which a specific protein in the body inhibits formation of new blood vessels. Inhibiting the formation of new blood vessels is an important aspect of, for example, cancer treatment. The study is published in the November issue of the journal Molecular Cancer Research.

12 Nov 2009

New research center established to improve cardiac safety

The University of Rochester Medical Center has announced the creation of a new center that will assist researchers studying the electrical activity of the heart with the goal of improving drug safety, understanding cardiac arrhythmias, and developing new electrocardiograph technologies.

12 Nov 2009

Some benefits from prescription drug DTCA, but significant risks remain

While the debate over prescription drug advertising persists, a new study released online in the American Journal of Public Health offers guidelines for improving drug ads in order to minimize potential harm and maximize benefits. The study reveals that while there are some benefits from prescription drug direct-to-consumer advertising (DTCA), there are significant risks that are magnified by the prominence of DTCA.

12 Nov 2009

Researchers find link between telomeres and longevity

A team led by researchers at Albert Einstein College of Medicine of Yeshiva University has found a clear link between living to 100 and inheriting a hyperactive version of an enzyme that rebuilds telomeres - the tip ends of chromosomes. The findings appear in the latest issue of the Proceedings of the National Academy of Sciences.

12 Nov 2009

Psychiatrist delivers high-risk meds, poor care in Chicago nursing homes

ProPublica/The Chicago Tribune examine the case of a controversial psychiatrist who delivered an anti-psychotic medication to thousands of Medicaid patients in Chicago's nursing homes. "Dr. Michael Reinstein is one of the most prolific providers of psychiatric care in Chicago-area nursing homes and mental health facilities. But he is trailed by lawsuits and complaints while getting government reimbursement for seeing a large number of patients."

12 Nov 2009

Drug companies collaborate with nonprofit organizations to fight "neglected" diseases in the developing world

Drug companies and nonprofit organizations are joining forces to develop new drugs and vaccines to target so-called "neglected" diseases that claim millions of lives in the developing world each year. Those hard-to-treat diseases include malaria, tuberculosis, dengue fever, and other conditions. That's the topic of the cover story scheduled for the current issue of Chemical & Engineering News, ACS' weekly newsmagazine.

12 Nov 2009

Adamis Labs secures orders from three major wholesale distributers in U.S.

Adamis Pharmaceuticals Corporation (OTCBB: ADMP), announced today that its wholly owned subsidiary, Adamis Labs has now secured distribution contracts and initial stocking orders from the three major wholesalers of prescription drugs in the U.S.

11 Nov 2009

Athletes on performance-enhancing substances face increase risk of alcohol and drug related problems

College athletes who use performance-enhancing substances may be at heightened risk of misusing alcohol and using recreational drugs as well, according to new research in the Journal of Studies on Alcohol and Drugs.

11 Nov 2009

CVS settles with NY over expired product sales; NC gets high-risk pool payment help

New York Attorney General Andrew Cuomo announced Tuesday that CVS, the drug story chain, has agreed to pay $875,000 to settle charges that it sold products years after their expiration dates, Reuters reports. The out-dated products, sold at 142 different stores, included "over-the-counter drugs, baby formula, eggs and milk," and in some cases items were sold more than two years after expiring (Stempel, 11/10).

11 Nov 2009

FDA accepts Sol-Gel’s Investigational New Drug Application for DER45-EV Gel

Sol-Gel Technologies announced that the U.S. Food and Drug Administration (FDA) has acknowledged receipt of Sol-Gel’s Investigational New Drug Application (IND) for DER45-EV Gel for the topical treatment of rosacea. This IND allows Sol-Gel to initiate Phase II studies with DER45-EV Gel in rosacea patients.

11 Nov 2009

Report on the U.S. Government's drive for comparative effectiveness research

MarketResearch.com has announced the addition of GlobalData's new report "The US Government's Financial Support to Push Comparative Effectiveness Research," to their collection of Healthcare market reports.

11 Nov 2009

WebMD Health inks agreement with Drugs.com

WebMD Health Corp., the leading source of health information, announced today that it has entered into an alliance with Drugs.com to exclusively integrate Drugs.com's advertising inventory and online traffic into the WebMD Health Network. Drugs.com provides free, accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products.

11 Nov 2009

Cholesterol-lowering drugs associated with reduced risk of gallstone disease

Use of the cholesterol-lowering drugs statins for more than a year is associated with a reduced risk of having gallstones requiring surgery, according to a study in the November 11 issue of JAMA.

11 Nov 2009

Potential benefits of Labopharm's novel trazodone formulation published

Labopharm Inc. today announced an article has been published in the international journal of neuropsychiatric medicine, CNS Spectrums October, 2009 issue, citing the potential benefit of its novel trazodone formulation, which contains Contramid(R). Labopharm's Contramid is the clinically validated proprietary technology that controls the release of active substances from oral medications to optimize drug delivery.

11 Nov 2009

Drugs News and Research

Millennium Laboratories announces new clinical quantitative assay and drug screening tests for healthcare

Stapled Peptides can inhibit key intracellular biological targets, says new research

Novel breakthrough may lead to new methods for sterilizing food and medical equipment

Scientists report largest-ever collection of data about the proteins produced by genes in a single human organ

IMS Health to launch comprehensive analytical tool for oncology market

Scientists find way to disarm "undruggable" protein; discovery lays foundation for new kind of cancer therapy

Researchers identify a new mechanism that inhibits the formation of new blood vessels

New research center established to improve cardiac safety

Some benefits from prescription drug DTCA, but significant risks remain

Researchers find link between telomeres and longevity

Psychiatrist delivers high-risk meds, poor care in Chicago nursing homes

Drug companies collaborate with nonprofit organizations to fight "neglected" diseases in the developing world

Adamis Labs secures orders from three major wholesale distributers in U.S.

Athletes on performance-enhancing substances face increase risk of alcohol and drug related problems

CVS settles with NY over expired product sales; NC gets high-risk pool payment help

FDA accepts Sol-Gel’s Investigational New Drug Application for DER45-EV Gel

Report on the U.S. Government's drive for comparative effectiveness research

WebMD Health inks agreement with Drugs.com

Cholesterol-lowering drugs associated with reduced risk of gallstone disease

Potential benefits of Labopharm's novel trazodone formulation published

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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