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New 3D model reveals hidden role of stem cells in sense of smell

Using a newly devised, three-dimensional model to study the regeneration of nerve tissue in the nose, researchers at Tufts University School of Medicine and the Graduate School of Biomedical Sciences (GSBS) and colleagues have discovered that one type of stem cell thought to be dormant may play a more significant role in preserving the sense of smell than originally believed.

11 Jun 2025

Glucocorticoid receptor plays dual role in prostate cancer progression

A recent study from the Institute of Biomedicine at the University of Eastern Finland shows that the glucocorticoid receptor can both promote and inhibit prostate cancer progression, depending on the circumstances.

11 Jun 2025

Memory neurons in rats may explain why forgetting meals leads to overeating

Researchers identify "meal memory" neurons in laboratory rats that could explain why forgetting lunch leads to overeating.

11 Jun 2025

Antibiotic use predicts microbiota dysbiosis in preterm infants

Antibiotic use in preterm infants is linked to gut microbiome changes, increasing susceptibility to infections and impacting long-term health outcomes.

11 Jun 2025

Enhanced Genomics appoints Dietrich Stephan, Ph.D. as Chair of the Board to lead ambitious growth strategy

Enhanced Genomics (‘Enhanced’ or ‘the Company’), the biotechnology company pioneering 3D multi-omics to rapidly identify high-confidence, genetically validated drug targets for common diseases, today announced the appointment of Dietrich Stephan, Ph.D. as Chair of the Board of Directors.

11 Jun 2025

CHAF1B drives lung squamous cell carcinoma progression by repressing SETD7

CHAF1B, a histone chaperone component of the chromatin assembly factor-1 complex, is overexpressed in multiple cancers and linked to tumor progression, but its role in lung squamous-cell carcinoma (LUSC) remained unclear.

11 Jun 2025

Tufts researchers design new generation of weight loss medications

Weight loss drugs like Ozempic and Wegovy are used by over 15 million adults in the U.S., or 4.5% of the population. Despite their effectiveness, they have drawbacks.

11 Jun 2025

Targeting metabolic reprogramming in breast cancer treatment

Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health.

11 Jun 2025

ISSCR updates guidelines for oversight and regulation of stem cell-based embryo models

The International Society for Stem Cell Research (ISSCR) Embryo Models Working Group has released updated recommendations for the oversight and regulation of stem cell-based embryo models (SCBEM), aiming to address rapid advancements and ensure responsible scientific progress.

11 Jun 2025

Eva1 targeted CAR T cells successfully eliminate tumors in preclinical study

CAR-T cells are specialized immune cells genetically modified to recognize and attack cancer cells. Researchers at Nagoya University in Japan and their collaborators have developed new CAR-T cells to target malignant tumors.

11 Jun 2025

Scientists discover hundreds of new metabolites linked to the human microbiome

Human metabolism is a complex web of chemical processes and interactions between our cells and the microbes living within us.

10 Jun 2025

Eliminating stellate cells reduces liver metastasis in mouse models

The prestigious journal Hepatology Communications reports on the discovery by the Cancer and Translational Medicine research group of the University of the Basque Country (EHU).

10 Jun 2025

Study reveals a unique vulnerability in melanoma patients with neurofibromin 1 mutations

Increased activity in a specific biological pathway may explain why many patients with a deadly form of skin cancer do not respond to the latest cancer treatments, a new study shows.

10 Jun 2025

Methylation clocks may mislead anti-aging therapy evaluation

A new research perspective was published in Aging (Aging-US) Volume 17, Issue 5, on May 5, 2025, titled "Methylation clocks for evaluation of anti-aging interventions."

10 Jun 2025

Simulation training at NYU Langone helps cut stroke response times

When it comes to treating strokes, time-to-intervention is most critical. About 1.9 million brain cells die on average for each minute that a large vessel stroke goes untreated.

10 Jun 2025

Novel self-propelled ferroptosis nanoinducer achieves deeper penetration into tumor tissues

A novel self-propelled ferroptosis nanoinducer developed by Southern Medical University was able to achieve deeper penetration into tumor tissues to show enhanced anti-cancer effects, while remaining considerable biocompatibility.

10 Jun 2025

Inhibiting cancer cells' energy source with natural acid ester

Looking to nature for answers to complex questions can reveal new and unprecedented results that can even affect cells on molecular levels.

10 Jun 2025

Early signs of breastfeeding failures after premature birth

A study on breastfeeding after premature birth identifies key factors affecting milk composition and volume, emphasizing the need for early support for mothers.

10 Jun 2025

Patient-derived xenograft models may become an indispensable tool in precision oncology

Cancer remains one of the most pressing global health challenges, with millions of new diagnoses each year. While precision medicine and targeted therapies have transformed treatment strategies, many patients still face drug resistance and disease recurrence.

10 Jun 2025

Manganese-coordinated lipid nanoparticles boost VZV vaccine-induced T cell responses

Announcing a new article publication for Zoonoses journal. Because varicella zoster virus (VZV) infections are continually increasing, vaccine efficacy must be enhanced.

10 Jun 2025