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A reliable way to replicate α-synuclein aggregation on cell membranes in Parkinson's disease patients

The accumulation of α-synuclein, a small, negatively charged protein, in neural cells, is one of the hallmarks of Parkinson's disease. It has been suggested that oligomeric α-synuclein causes membranes to become permeable, or to form channels on the outer cell membrane.

19 Jan 2012

Converted umbilical cord stem cells hold hope for spinal cord injuries, multiple sclerosis

For the first time ever, stem cells from umbilical cords have been converted into other types of cells, which may eventually lead to new treatment options for spinal cord injuries and multiple sclerosis, among other nervous system diseases.

18 Jan 2012

Bioengineers receive $2 million NIH grant to develop new toxicology tests

Chemicals in pharmaceutical drugs can obviously save lives. But as more and stronger chemicals have been introduced, our basic knowledge of the broader health impact of all these chemicals has not kept up with the rapid pace of innovation. There is exceptionally little information on how chemicals in our drugs and also in the environment around us, including on the food we eat, impact some of the most important cells in our body: stem cells. Without basic knowledge and tests on the impact of chemicals on our stem cells, we may be unwittingly damaging essential regenerative functions in our body.

18 Jan 2012

Links between deodorants and breast cancer refuted but more information needed: Study

A chemical present in cosmetics, food products and pharmaceuticals has been found in tissue samples from 40 women with breast cancer. A number of studies since 1998 have raised concerns about the potential role of these chemicals called parabens in breast cancer as they possess estrogenic properties. Estrogen is known to play a central role in the development, growth and progression of breast cancer.

16 Jan 2012

IBM's non-contact, microfluidic, silicon probe minimizes patient discomfort

IBM scientists have developed a flexible, non-contact microfluidic probe made from silicon that can aid researchers and pathologists to investigate critical tissue samples accurately for drug discovery and disease diagnostics.

13 Jan 2012

Scientists identify chemical signals that promote aggregation in roundworms

Scientists have long seen evidence of social behavior among many species of animals, both on the earth and in the sea. Dolphins frolic together, lions live in packs, and hornets construct nests that can house a large number of the insects. And, right under our feet, it appears that nematodes-also known as roundworms-are having their own little gatherings in the soil. Until recently, it was unknown how the worms communicate to one another when it's time to come together.

13 Jan 2012

CDC, NIST develop two new SRMs for measurements of toxic environmental chemicals

The National Institute of Standards and Technology (NIST), in collaboration with the Centers for Disease Control and Prevention (CDC), has developed two new Standard Reference Materials (SRMs) for measurements of human exposure to environmental toxins.

12 Jan 2012

Low-voltage alternating current can effectively eradicate E. coli on beef

A short burst of low voltage alternating current can effectively eradicate E. coli bacteria growing on the surface of even heavily contaminated beef, according to a study published in the International Journal of Food Safety, Nutrition and Public Health. The technique offers an inexpensive and easy to implement approach to reducing the risk of food poisoning, which can occur despite handlers complying with hygiene standards.

12 Jan 2012

Novel nanosensors can lead to fewer experiments on animals

Countless mice, rats and rabbits die every year in the name of science - and the situation is getting worse. While German laboratories used some 2.41 million animals for scientific research in 2005, by 2009 this number had grown to 2.79 million. One third were destined for fundamental biology research, and the majority were used for researching diseases and developing medical compounds and devices.

11 Jan 2012

Warwick researchers and Canadian scientists partner in new project on antibiotic resistance

University of Warwick researchers have teamed up with Canadian scientists on a -2.2 million project to search for new antibiotics which will beat resistance in deadly "superbugs".

11 Jan 2012

Fallujah doctors say chemicals from U.S. weapons to blame for high levels of birth defects

"While the U.S. military has formally withdrawn from Iraq, doctors and residents of Fallujah are blaming weapons like depleted uranium and white phosphorous used during two devastating U.S. attacks on Fallujah in 2004 for what are being described as 'catastrophic' levels of birth defects and abnormalities," Al Jazeera reports.

10 Jan 2012

Major tobacco company manipulates data on effects of additives in cigarettes

A new UCSF analysis of tobacco industry documents shows that Philip Morris USA manipulated data on the effects of additives in cigarettes, including menthol, obscuring actual toxicity levels and increasing the risk of heart, cancer and other diseases for smokers.

7 Jan 2012

Drinking red wine in moderation may reduce risk of breast cancer

Drinking red wine in moderation may reduce one of the risk factors for breast cancer, providing a natural weapon to combat a major cause of death among U.S. women, new research from Cedars-Sinai Medical Center shows.

7 Jan 2012

Researchers crack structure and function of malarial protein

A biology lab at Washington University has just cracked the structure and function of a protein that plays a key role in the life of a parasite that killed 655,000 people in 2010.

7 Jan 2012

Scientists identify how dihydromyricetin counteracts acute alcohol intoxication

UCLA researchers have identified how a component of an ancient Chinese herbal anti-hangover medicine called dihydromyricetin, isolated from the plant Hovenia, counteracts acute alcohol intoxication and withdrawal symptoms.

6 Jan 2012

Researchers urged to differentiate between two bladder cancer subtypes in their studies

Researchers are being urged to differentiate between two types of bladder cancer when they carry out studies, after a detailed trends analysis revealed significant differences between the main subtypes of the disease.

5 Jan 2012

NovaSterilis awarded soft tissue processing patent

NovaSterilis Inc., specializing in developing applications for supercritical carbon dioxide, has been granted US Patent 8,034,288 B2. The patent, dated October 11, 2011 entitled “Method and Apparatus for Cleaning of Viable Donor Soft Tissue”, covers a new method for cleaning soft allograft tissue including tendon, fascia, and skin with a supercritical fluid, thus avoiding other harmful chemical solvents that may leave residual chemicals.

4 Jan 2012

New standards to ensure quality of probiotic food ingredients proposed

With strong consumer interest in probiotics-and new manufacturer innovations for incorporating these ingredients into a broader array of food products-new standards to help ensure the quality of probiotic food ingredients are being proposed for public review and comment.

4 Jan 2012

Scientists discover chemical compound that inhibits poxviruses from replicating

A team of scientists from Boston University School of Medicine (BUSM) have identified a novel compound that inhibits viruses from replicating. The findings, which are published online in the Journal of Virology, could lead to the development of highly targeted compounds to block the replication of poxviruses, such as the emerging infectious disease Monkeypox.

4 Jan 2012

FDA notes shortage of ADHD medicines

According to the U.S. Food and Drug Administration (FDA) drugs to treat attention deficit hyperactivity disorder (ADHD) are in such short supply that hundreds of patients complain daily to the agency that they are unable to find a pharmacy with enough pills to fill their prescriptions.

2 Jan 2012