B Cell News and Research

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Scientists solve mystery behind what triggers the herpes virus to become active again

The mere mention of the word "herpes" usually conjures negative images and stereotypes, but most people have been infected with some form of the virus. For most, a sore appears, heals and is forgotten, although the virus remains latent just waiting for the right circumstances to come back. Now, the mystery behind what triggers the virus to become active again is closer to being solved thanks to new research published in the Journal of Leukocyte Biology's November 2012 issue.

1 Nov 2012

Biomarker discovery offers hope for lung cancer blood test

Blood levels of a variant form of the nuclear matrix protein Ciz1 are significantly higher in individuals with early- and late-stage lung cancer than in lung cancer-free individuals, researchers report.

31 Oct 2012

Pins made of single atoms to fight cancer

Answers are often elusive in the fight against cancer, and Rice University chemist Zachary Ball is hoping to pin one down -- with pins made of single atoms. The work, which aims to create a drug that's effective against an "undruggable" protein, is one of the first 50 proposals funded under the National Cancer Institute's (NCI) Provocative Questions Project.

31 Oct 2012

EC grants conditional marketing authorisation for ADCETRIS to treat hematological cancers

Takeda Pharmaceutical Company Limited and Millennium: The Takeda Oncology Company, today announced that the European Commission has granted conditional marketing authorisation for ADCETRIS (brentuximab vedotin) for two indications.

31 Oct 2012

Viewpoints: Wilensky on 'ending Medicare as we've known it'; Abortion politics, the election and 'absolutists'

Democrats have charged Republicans with "ending Medicare as we've known it" and have been generally successful in making that claim stick in the mind of the public. The interesting fact is that Democrats have also "ended Medicare as we've known it" -- that is, as an open-ended entitlement -- but thus far, they seem to have escaped getting hit with the same label. If the [Independent Payment Advisory Board] ever actually goes into effect, it will be interesting to see whether they will continue to be successful at dodging their own charge.

31 Oct 2012

Researchers discover how tamoxifen-resistant breast-cancer cells grow and proliferate

A study by researchers at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) has discovered how tamoxifen-resistant breast-cancer cells grow and proliferate.

31 Oct 2012

Viscus Biologics to develop and commercialize NFB’s new tissue repair material

Viscus Biologics LLC, Cleveland, Ohio, has secured an 18-month option to conduct further research into the development and commercialisation of a new tissue repair material developed by the Network of Excellence for Functional Biomaterials (NFB) at National University of Ireland, Galway.

31 Oct 2012

Symposium to discuss latest scientific and clinical advances in treating non-Hodgkins lymphoma

Fifty world-renowned experts in non-Hodgkins lymphoma will convene in New York in November to present the latest scientific and clinical advances in treating a "lost generation" of sufferers-children, young adults and adolescents.

31 Oct 2012

Unique bond between SAP102 and GluN2B enables learning and memory

Two proteins have a unique bond that enables brain receptors essential to learning and memory to not only get and stay where they're needed, but to be hauled off when they aren't, researchers say.

31 Oct 2012

Complix to accelerate development of CPABs against intracellular disease targets

Complix announces that it has been awarded a €1.9 million grant (approximately USD$2.4 million) from the Flanders government through IWT (Agency for Innovation by Science and Technology in Flanders).

30 Oct 2012

STAT3 transcription factor remains in the axon of nerve cells to help prevent neurodegeneration

A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow nerve damage in patients with neurodegenerative diseases.

30 Oct 2012

Internet, smartphone apps represent prime venues for adolescent-targeted sexual health programs

The use of smartphones is associated with an increased likelihood of being solicited for sex on the internet, and having sex with an internet-met partner among teens, according to new research released today at the American Public Health Association's 140th Annual Meeting in San Francisco, Calif.

30 Oct 2012

Study identifies new prognostic biomarker and therapeutic target for adult B-ALL

New insight into the aggressive behavior of certain adult B-acute lymphoblastic leukemias has provided researchers with a potential new prognostic biomarker and a promising new therapeutic target.

30 Oct 2012

IPSCs may be a viable source of patient-specific articular cartilage tissue

A team of Duke Medicine researchers has engineered cartilage from induced pluripotent stem cells that were successfully grown and sorted for use in tissue repair and studies into cartilage injury and osteoarthritis.

30 Oct 2012

Researchers decode software instructions that drive 3 different forms of acute lymphoblastic leukemia

A team of national and international researchers, led by Weill Cornell Medical College scientists, have decoded the key "software" instructions that drive three of the most virulent forms of acute lymphoblastic leukemia (ALL).

30 Oct 2012

Array BioPharma first quarter 2013 revenue decreases to $15.8 million

Array BioPharma Inc. today reported results for the first quarter of its fiscal year ending June 30, 2013.

30 Oct 2012

Four transcription factor genes control processes related to heart and head muscle formation

A group of researchers in Israel, the United States and other nations have made important advances in the rapidly-expanding field of "regenerative medicine," outlining for the first time connections in genetic regulation that normally prevent birth defects in heart and facial muscles.

30 Oct 2012

Variation in size of red cell distribution width is linked with socioeconomic factors

It is well known that socioeconomic factors such as poverty and low education play a role in health, but new research released today at the American Public Health Association's 140th Annual Meeting in San Francisco, Calif., shows this association is also seen in biomarkers of the blood.

30 Oct 2012

Positive results from Celldex’s CDX-1401 Phase 1 study on solid tumors

Celldex Therapeutics, Inc. today announced positive results demonstrating promising clinical effects in a Phase 1 study of CDX-1401 in solid tumors in combination with the toll-like receptor (TLR) agonists resiquimod and/or Poly ICLC.

30 Oct 2012

Scientists discover β2-syntrophin protein as new prognosis marker for prostate cancer

Scientists have discovered a molecular 'tell' in laboratory experiments that could help doctors determine the severity of a patient's prostate cancer.

30 Oct 2012

B Cell News and Research

Scientists solve mystery behind what triggers the herpes virus to become active again

Biomarker discovery offers hope for lung cancer blood test

Pins made of single atoms to fight cancer

EC grants conditional marketing authorisation for ADCETRIS to treat hematological cancers

Viewpoints: Wilensky on 'ending Medicare as we've known it'; Abortion politics, the election and 'absolutists'

Researchers discover how tamoxifen-resistant breast-cancer cells grow and proliferate

Viscus Biologics to develop and commercialize NFB’s new tissue repair material

Symposium to discuss latest scientific and clinical advances in treating non-Hodgkins lymphoma

Unique bond between SAP102 and GluN2B enables learning and memory

Complix to accelerate development of CPABs against intracellular disease targets

STAT3 transcription factor remains in the axon of nerve cells to help prevent neurodegeneration

Internet, smartphone apps represent prime venues for adolescent-targeted sexual health programs

Study identifies new prognostic biomarker and therapeutic target for adult B-ALL

IPSCs may be a viable source of patient-specific articular cartilage tissue

Researchers decode software instructions that drive 3 different forms of acute lymphoblastic leukemia

Array BioPharma first quarter 2013 revenue decreases to $15.8 million

Four transcription factor genes control processes related to heart and head muscle formation

Variation in size of red cell distribution width is linked with socioeconomic factors

Positive results from Celldex’s CDX-1401 Phase 1 study on solid tumors

Scientists discover β2-syntrophin protein as new prognosis marker for prostate cancer

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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