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Scientists discover first selective inhibitors of DAGL enzymes

Scientists at The Scripps Research Institute (TSRI) have discovered the first selective inhibitors of an important set of enzymes. The new inhibitors, and chemical probes based on them, now can be used to study the functions of enzymes known as diacylglycerol lipases (DAGL), their products, and the pathways they regulate.

1 Nov 2012

Varian highlights numerous lung cancer treatment systems at ASTRO meeting

Varian Medical Systems highlighted the company's technologies for the non-invasive treatment of lung cancer at the 54th annual meeting of the American Society for Radiation Oncology (ASTRO) in Boston this week.

1 Nov 2012

Isis announces preliminary data from ISIS-STAT3 Phase 1 study on cancer

Isis Pharmaceuticals, Inc. announced that preliminary data from the Phase 1 study of ISIS-STAT3Rx in patients with cancer were presented today at the Oligonucleotide Therapeutics Society in Boston.

1 Nov 2012

Green tea may reduce risk of digestive system cancers among women

Women who drink green tea may lower their risk of developing some digestive system cancers, especially cancers of the stomach/esophagus and colorectum, according to a study led by researchers from Vanderbilt-Ingram Cancer Center.

1 Nov 2012

Scientists solve mystery behind what triggers the herpes virus to become active again

The mere mention of the word "herpes" usually conjures negative images and stereotypes, but most people have been infected with some form of the virus. For most, a sore appears, heals and is forgotten, although the virus remains latent just waiting for the right circumstances to come back. Now, the mystery behind what triggers the virus to become active again is closer to being solved thanks to new research published in the Journal of Leukocyte Biology's November 2012 issue.

1 Nov 2012

Biomarker discovery offers hope for lung cancer blood test

Blood levels of a variant form of the nuclear matrix protein Ciz1 are significantly higher in individuals with early- and late-stage lung cancer than in lung cancer-free individuals, researchers report.

31 Oct 2012

Pins made of single atoms to fight cancer

Answers are often elusive in the fight against cancer, and Rice University chemist Zachary Ball is hoping to pin one down -- with pins made of single atoms. The work, which aims to create a drug that's effective against an "undruggable" protein, is one of the first 50 proposals funded under the National Cancer Institute's (NCI) Provocative Questions Project.

31 Oct 2012

EC grants conditional marketing authorisation for ADCETRIS to treat hematological cancers

Takeda Pharmaceutical Company Limited and Millennium: The Takeda Oncology Company, today announced that the European Commission has granted conditional marketing authorisation for ADCETRIS (brentuximab vedotin) for two indications.

31 Oct 2012

Viewpoints: Wilensky on 'ending Medicare as we've known it'; Abortion politics, the election and 'absolutists'

Democrats have charged Republicans with "ending Medicare as we've known it" and have been generally successful in making that claim stick in the mind of the public. The interesting fact is that Democrats have also "ended Medicare as we've known it" -- that is, as an open-ended entitlement -- but thus far, they seem to have escaped getting hit with the same label. If the [Independent Payment Advisory Board] ever actually goes into effect, it will be interesting to see whether they will continue to be successful at dodging their own charge.

31 Oct 2012

Researchers discover how tamoxifen-resistant breast-cancer cells grow and proliferate

A study by researchers at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) has discovered how tamoxifen-resistant breast-cancer cells grow and proliferate.

31 Oct 2012

Viscus Biologics to develop and commercialize NFB’s new tissue repair material

Viscus Biologics LLC, Cleveland, Ohio, has secured an 18-month option to conduct further research into the development and commercialisation of a new tissue repair material developed by the Network of Excellence for Functional Biomaterials (NFB) at National University of Ireland, Galway.

31 Oct 2012

Symposium to discuss latest scientific and clinical advances in treating non-Hodgkins lymphoma

Fifty world-renowned experts in non-Hodgkins lymphoma will convene in New York in November to present the latest scientific and clinical advances in treating a "lost generation" of sufferers-children, young adults and adolescents.

31 Oct 2012

Unique bond between SAP102 and GluN2B enables learning and memory

Two proteins have a unique bond that enables brain receptors essential to learning and memory to not only get and stay where they're needed, but to be hauled off when they aren't, researchers say.

31 Oct 2012

Complix to accelerate development of CPABs against intracellular disease targets

Complix announces that it has been awarded a €1.9 million grant (approximately USD$2.4 million) from the Flanders government through IWT (Agency for Innovation by Science and Technology in Flanders).

30 Oct 2012

STAT3 transcription factor remains in the axon of nerve cells to help prevent neurodegeneration

A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow nerve damage in patients with neurodegenerative diseases.

30 Oct 2012

Internet, smartphone apps represent prime venues for adolescent-targeted sexual health programs

The use of smartphones is associated with an increased likelihood of being solicited for sex on the internet, and having sex with an internet-met partner among teens, according to new research released today at the American Public Health Association's 140th Annual Meeting in San Francisco, Calif.

30 Oct 2012

B Cell News and Research

Scientists discover first selective inhibitors of DAGL enzymes

Varian highlights numerous lung cancer treatment systems at ASTRO meeting

Isis announces preliminary data from ISIS-STAT3 Phase 1 study on cancer

Green tea may reduce risk of digestive system cancers among women

Scientists solve mystery behind what triggers the herpes virus to become active again

Biomarker discovery offers hope for lung cancer blood test

Pins made of single atoms to fight cancer

EC grants conditional marketing authorisation for ADCETRIS to treat hematological cancers

Viewpoints: Wilensky on 'ending Medicare as we've known it'; Abortion politics, the election and 'absolutists'

Researchers discover how tamoxifen-resistant breast-cancer cells grow and proliferate

Viscus Biologics to develop and commercialize NFB’s new tissue repair material

Symposium to discuss latest scientific and clinical advances in treating non-Hodgkins lymphoma

Unique bond between SAP102 and GluN2B enables learning and memory

Complix to accelerate development of CPABs against intracellular disease targets

STAT3 transcription factor remains in the axon of nerve cells to help prevent neurodegeneration

Internet, smartphone apps represent prime venues for adolescent-targeted sexual health programs

Study identifies new prognostic biomarker and therapeutic target for adult B-ALL

IPSCs may be a viable source of patient-specific articular cartilage tissue

Researchers decode software instructions that drive 3 different forms of acute lymphoblastic leukemia

Array BioPharma first quarter 2013 revenue decreases to $15.8 million

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