Blood Transfusion News and Research

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Blood transfusion is the process of transferring blood or blood-based products from one person into the circulatory system of another. Blood transfusions can be life-saving in some situations, such as massive blood loss due to trauma, or can be used to replace blood lost during surgery.

GDC-0449 inhibits the Hedgehog signaling pathway

The Hedgehog signaling pathway is involved in a preliminary study and case report describing positive responses to an experimental anticancer drug in a majority of people with advanced or metastatic basal cell skin cancers. One patient with the most common type of pediatric brain cancer, medulloblastoma, also showed tumor shrinkage.

3 Sep 2009

FDA recommends electronic report formats to strengthen postmarket safety data collection

The U.S. Food and Drug Administration is proposing to amend postmarket safety reporting regulations for three of its centers to require that manufacturers and other facilities subject to current reporting requirements submit their reports in an electronic format.

26 Aug 2009

Cerus Corporation to raise approximately $12.2 million by selling stocks and warrants

Cerus Corporation (NASDAQ:CERS) today announced that it has entered into definitive agreements with selected investors to sell 6,000,000 units, with each unit consisting of (i) one share of the Company’s common stock and (ii) a warrant to purchase 0.4 of a share of the Company’s common stock for gross proceeds of approximately $13.2 million in a “registered direct” offering.

21 Aug 2009

Mandatory folic acid fortification may be unnecessary

Persistently present levels of unmetabolized folic acid found in the population indicate that introducing mandatory food fortification may result in an ‘overdosing’ effect. A study of blood donors, new mothers and babies, published in the open access journal BMC Public Health, has found that most already get enough folic acid from voluntarily fortified foods.

17 Aug 2009

New immune therapy for kidney cancer tested

Researchers at The Cancer Institute of New Jersey (CINJ) have opened a clinical trial to evaluate whether the standard treatment for a common form of kidney cancer works better by itself or when combined with a certain type of blood cell that comes from a patient’s relative. CINJ is a Center of Excellence of UMDNJ-Robert Wood Johnson Medical School.

14 Aug 2009

Less is more when it comes to blood transfusions

A new study suggests that blood transfusions for hospitalized cardiac patients should be a last resort because they double the risk of infection and increase by four times the risk of death.

5 Aug 2009

Blood transfusions associated with infection

A study of almost 25,000 coronary artery bypass graft (CABG) patients has shown that receiving blood from another person is associated with a two-fold increase in post-operative infection rates. The research, published in the open access journal BMC Medicine, also found considerable hospital variation in transfusion practices.

30 Jul 2009

Hepatitis C infection: Treatment options equally effective, likelihood of success known early on

Results of a long-awaited study of 3,070 American adults at Johns Hopkins and 118 other U.S. medical centers show that treatment with either of the two standard antiviral drug therapies is safe and offers the best way for people infected with hepatitis C to prevent liver scarring, organ failure and death.

22 Jul 2009

Kenya seeks support from PEPFAR to expand blood transfusion centers

Kenya's Medical Services Permanent Secretary James Ole Kiyiapi announced Thursday that the government is in negotiations with PEPFAR for support in building additional blood transfusion centers in the country, Capital News reports.

29 Jun 2009

Research supports world blood donor day message on blood safety

Other countries could learn from the mistakes made in UK blood policy concludes research awarded by the Economic and Social Research Council's Michael Young Prize.

13 Jun 2009

Women with heavy periods may have an undiagnosed bleeding disorder

According to researchers in the United States many women suffer from bleeding disorders, but are unaware they have one because doctors are not looking for the condition.

3 Jun 2009

Bleeding disorders going undiagnosed; new guidelines to help

Nearly one percent of the population suffers from bleeding disorders, yet many women don't know they have one because doctors aren't looking for the condition, according to researchers at Duke University Medical Center.

2 Jun 2009

Hospital refuses admission to young adults with thalassemia and sickle cell disease

Young adults with thalassemia and sickle cell diease have been trying for up to 10 years to gain admission to the only adult hospital program in central and southwestern Toronto specialized to treat their blood disorders. Since 1999, the Toronto General Hospital (TGH) has restricted the inherited blood disorders program to 99 patients requiring blood transfusions. As a result, about 150 young adults with complex disorders receive blood transfusions at the Hospital for Sick Children but no adult services.

25 May 2009

Blood transfusions after cardiac surgery may be unnecessary

Blood transfusions carried out after cardiac surgery could be unnecessary and might cause health complications for patients.

15 Apr 2009

Screening to help prevent stroke in kids increases, but limited access a problem

The number of children with a certain blood disorder undergoing an ultrasound to help prevent stroke is up significantly in the past 10 years since the publication of a major study showing its benefits.

13 Apr 2009

New blood fights cancer

"New blood" can revitalize a company or a sports team. Recent research by Tel Aviv University finds that young blood does a body good as well, especially when it comes to fighting cancer.

1 Jan 2009

Evaluation of treatments for benign prostatic enlargement

Research published by the National Institute for Health Research Health Technology Assessment (NIHR HTA) programme has found that transurethral resection, the most common operation for benign prostatic enlargement (BPE), remains a clinically and cost-effective treatment. BPE commonly causes older men to have difficulty passing urine and may require surgery to alleviate the problem.

18 Dec 2008

New Web-based tool for tracking blood safety

The Georgia Tech College of Computing, working in partnership with the Centers for Disease Control and Prevention, has developed a Web-based tool for tracking blood safety.

10 Dec 2008

Study identifies characteristics of hospitals with low rates of surgical site infections

New research published in the December issue of the Journal of the American College of Surgeons (JACS) suggests that surgical procedures that are shorter in duration and the use of fewer blood transfusions characterize hospitals that have a lower incidence of surgical site infections (SSI).

8 Dec 2008

Routine HIV screening for all patients recommended

On World AIDS Day, the American College of Physicians (ACP) is giving doctors a call-to-action to routinely encourage HIV screening to all of their patients older than 13 years.

1 Dec 2008