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Verastem doses first patient in Phase I/II clinical trial of duvelisib in combination with venetoclax

Verastem, Inc., operating as Verastem Oncology, a biopharmaceutical company focused on developing and commercializing medicines to improve the survival and quality of life of cancer patients, today announced dosing of the first patient in a multicenter Phase I/II clinical trial at the Dana-Farber/Harvard Cancer Center of duvelisib in combination with venetoclax in patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma.

6 Sep 2018

New study reports key steps towards development of acne vaccine

A new study published in the Journal of Investigative Dermatology reports important steps that have been taken towards the development of an acne vaccine.

29 Aug 2018

Natural enzyme found in the human lungs can biodegrade graphene

Graphene Flagship partners discovered that a natural human enzyme can biodegrade graphene. These findings could have great implications in the development of graphene-based biomedical devices.

23 Aug 2018

RBC-hitchhiking method increases concentration of drugs ferried to selected organs

A new drug-delivery technology which uses red blood cells to shuttle nano-scale drug carriers, called RBC-hitchhiking, has been found in animal models to dramatically increase the concentration of drugs ferried precisely to selected organs, according to a study published in Nature Communications this month by researchers from the Perelman School of Medicine at the University of Pennsylvania.

2 Aug 2018

MicroRNA panel could categorize indeterminate thyroid nodule samples into malignant and benign

A panel of 19 microRNAs identified using next-generation sequencing could categorize indeterminate thyroid nodule samples into malignant and benign.

26 Jul 2018

KIYATEC enrolls first patients with solid tumors in clinical study of its EV3D drug response assay

KIYATEC, Inc. today announced the enrollment of the first patients in a U.S. clinical study of its Ex Vivo 3D drug response assay across several difficult-to-treat solid tumors.

20 Jun 2018

Researchers use optogenetics to shape tissues

Constructing biological tissues, such as skin, muscle, or bone, in customized shapes is now one step closer.

19 Jun 2018

Study shows how moderate consumption of alcohol can protect the heart

For at least 20 years, research has shown that for many people, moderate consumption of alcohol can protect the heart, but the reason for this is poorly understood.

18 Jun 2018

Studies show link between innovation and reduced surgery complications

Exciting data from the 26th European Society of Thoracic Surgeons meeting shows an association between innovation, and improved patient outcomes and lowered hospital costs

13 Jun 2018

Gas embolotherapy holds great potential for treating cancer

Embolization -- the use of various techniques to cut off the blood vessels that feed tissue growth -- has gained traction over the past few decades to treat cancerous tumors.

6 Jun 2018

Investigational technology could increase donor organ supply for lung transplants

As many as 80 percent of lungs from organ donors are not used, either because they are not in good enough condition to transplant, or there are doubts about their quality and there is no way to verify their condition.

23 May 2018

Using Cord Blood to Alleviate the Symptoms of Autism

Cord blood has been studied extensively for the treatment of hematological diseases such as cancer and sickle cell anemia, but is now in phase II trials for the alleviation of autism. Dr. Ann Smith, director of Smart Cells who provided the cord blood for the trial, discusses the research and it's potential.

9 Apr 2018

New ocular inserts allow patient's cornea to absorb more antibiotics

The anatomic and physiologic structure of the eyes constitutes by itself an important barrier when administering medicine. The amount of medicine that passes through the cornea by applying creams or drops is very limited and it is necessary to develop alternative, more effective ways of administering them ocularly.

22 Mar 2018

Novel oncolytic virus expressing BiTE molecule elicits T cell-mediated killing of tumor cells

In a research article published in EMBO Molecular Medicine, a group of scientists at the University of Oxford have described a new twist on cancer immunotherapy, combining two independent cell killing approaches in a single therapeutic with high potency and broad applicability.

13 Mar 2018

NETRF awards six new research grants to improve treatments for neuroendocrine tumors

The Neuroendocrine Tumor Research Foundation today awarded six new research grants totaling $1.85 million to leading academic institutions around the world.

5 Mar 2018

Scientists explore factors that most affect our immune system

Why do we respond differently to infections or vaccines? Why are some people allergic to pollen? These are still unanswered questions in biological and medical science.

28 Feb 2018

Clinical trial studying type 1 diabetes reaches full enrollment

A clinical trial studying type 1 diabetes has reached full enrollment. The Sanford Project: T-Rex Study, a Phase 2 clinical trial conducted collaboratively by Sanford Health and Caladrius Biosciences, Inc., has completed enrollment of 110 children with type 1 diabetes. The study started with two sites at Sanford Health in Sioux Falls, South Dakota, and Fargo, North Dakota, and expanded to 13 additional sites across the United States.

19 Feb 2018

Cell membrane nanofragments can act as nucleation sites for mineralization during bone formation

The burst of cells forming cartilage is associated with mineralization during the early stages of bone formation, and nanofragments of the cell membranes can act as nucleation sites for amorphous calcium phosphate, as reported in two studies just published in Integrative Biology and ASC Biomaterials Science and Engineering.

14 Feb 2018

MILabs completes installation of latest VECTor5CT system at University of Copenhagen

MILabs announced today that it has successfully completed the installation of its top-of-the-line multimodality PET-SPECT-UHR CT in the laboratory of Prof. Maiken Nedergaard, M.D, D.M.Sci. – Center for Translational Neuroscience, Division of Glial Disease and Therapeutics.

6 Feb 2018

VUMC reaches new record in performing heart transplants

Vanderbilt University Medical Center performed a record number of heart transplants in 2017, surpassing the 2016 milestone and securing its place as the second-busiest heart transplant program in the country.

5 Feb 2018