Exhaustion News and Research

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Which population does extreme heat affect the most?

In this interview, we speak to Professor Gregory Wellenius about his latest research into extreme heat and how it may affect younger adults more than older adults.

16 Dec 2021

Out-of-hours work can have a significant impact on employees' physical and mental wellbeing

When the holiday season rolls around, will you get to relax, or do you let work creep into your down time? If you fit in the latter category and can’t seem to keep work at bay, you may be putting your health at risk, according to research from the University of South Australia.

16 Dec 2021

When the surges just keep coming: A view from the covid vortex

Dr. Rais Vohra has impeccable timing. He stepped into his role as interim health officer of Fresno County just months before the start of the covid-19 pandemic.

7 Dec 2021

Meth use and intimate partner violence drive exhaustion of immune cells in HIV patients

A study of HIV-positive black and Latino men who have sex with men finds the use of methamphetamine combined with intimate partner violence boosted the activity of genes that regulate the body's inflammatory and antiviral functions

6 Dec 2021

Review: Diagnostic radiologists at higher risk of burnout

A review co-authored by Dr. Bradley Spieler, Vice-Chair of Scholarly Activity and Research in the Department of Radiology at LSU Health New Orleans School of Medicine, and Dr. Neil Baum, of Tulane's Department of Urology, reports that although burnout affects more than 50% of health care workers, diagnostic radiologists are at even higher risk.

4 Dec 2021

Penn researchers illuminate key molecular details of T-cell exhaustion process

Specially engineered immune cells called CAR T cells have proven themselves to be a powerful weapon against blood cancers, but against solid tumors they are much less effective, due in part to a process called T-cell exhaustion.

2 Dec 2021

Researchers mapping the extent of IBD in the UK are seeking people's help

Scientists mapping the extent of Inflammatory Bowel Disease (IBD) in the UK are asking the public to help. Crohn's Disease and Ulcerative Colitis are the two main forms of IBD and affect more than 500,000people in theUK.

1 Dec 2021

Researchers examine the impact of prolonged COVID-19 pandemic on psychiatric symptoms

Family and friends who have become social recluses, or co-workers who feel depressed and are unable to come to work...most of us probably know someone in one of these situations.

12 Nov 2021

Study opens a window for new therapeutic approaches to ovarian cancer

A Ludwig Cancer Research study has uncovered a cellular interaction that is essential to the ability of the immune system's cytotoxic T lymphocytes to destroy ovarian tumors and shown that its engagement could help determine the efficacy of checkpoint blockade immunotherapy in a variety of cancers.

6 Nov 2021

Labs with no one to run them: Why public health workers are fleeing the field

There were days, nights and weekends in the early months of the pandemic when Denise Von Bargen was the only person running covid tests at the public health lab in Ventura County. She once had eight or nine employees to assist her, but, one by one, they had all retired or left for other jobs.

2 Nov 2021

Researchers decipher when and why T cells become non-responsive to immunotherapy

Non-small cell lung cancer is the most common type of lung cancer in humans. Some patients with NSCLC receive a therapy called immune checkpoint blockade (ICB) that helps kill cancer cells by reinvigorating a subset of immune cells called T cells, which are "exhausted" and have stopped working.

30 Oct 2021

Study highlights the factors that cause occupational burnout syndrome in professional drivers

Occupational burnout syndrome may lead to an increase in collisions involving professional drivers and injuries in the workplace.

29 Oct 2021

MU researchers receive $1.9 million grant to assess COVID-19 response in nursing homes

When Lori Popejoy and Amy Vogelsmeier were working as registered nurses early in their careers, they saw firsthand how quickly respiratory infections, such as the common flu, could spread in nursing homes.

27 Oct 2021

Study finds inadequate guidance and counseling for working-age people living with dementia

The right of working-age people living with dementia to receive adequate and timely guidance and counseling is not realized properly, a new study from the University of Eastern Finland shows.

27 Oct 2021

Influence of age on innate and adaptive immunity in COVID-19 patients

A new study investigates how age influences SARS-CoV-2 replication, innate and adaptive immune responses.

21 Oct 2021

New study shows how COVID-19 response has impacted the U.S. public health system

The cruel impact of COVID-19, the virus that emerged in late 2019 and has claimed 5 million lives to date, is chronicled in daily headlines. It has robbed us of loved ones, jobs, plans and so much more.

15 Oct 2021

Study reveals how to improve overall immune response against virally driven cancers

Blocking the PD-1 inhibitory pathway within a subset of specialized T-cells may improve overall immune response against virally driven cancers, according to findings published in Nature.

30 Sep 2021

Study findings could lead to novel ways to overcome tumor resistance to immunotherapies

Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different "program" that makes them less effective than immune cells in patients whose cancers respond to these immune treatments, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy.

22 Sep 2021

Many cancer survivors continue to suffer long-term burdensome symptoms, study shows

Previous standards of cancer follow-up care and support may no longer meet current needs as improvements in screening practices, early diagnosis and treatment of cancer have put long-term survival beyond five years following diagnosis within reach for more than half of patients in Europe.

20 Sep 2021

Study highlights the importance of deeply exploring the immune responses against cancer

Over the past decade, scientists have been exploring vaccination as a way to help fight cancer. These experimental cancer vaccines are designed to stimulate the body's own immune system to destroy a tumor, by injecting fragments of cancer proteins found on the tumor.

16 Sep 2021