Gene Editing News and Research

RSS

Brain's glucose metabolism: Key to unlocking new therapies for Alzheimer's and Parkinson's

...

20 Apr 2023

Precise genome editing approach can correct mutation that causes sickle cell disease

Scientists at St. Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard showed how prime editing can correct the mutation that causes sickle cell disease in a potentially curative approach.

18 Apr 2023

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

The standard treatment for patients with multiple myeloma often includes stem cell transplantation in which the patient's own stem cells are harvested and stored while the patient receives intensive chemotherapy to kill the cancer.

17 Apr 2023

Using the gene-editing tool to model certain liver tumor subtypes

Mutations in our genes can lead to severe problems, like colon or liver cancer. But cancer is very complex.

10 Apr 2023

New finding in roundworms upends classical thinking about animal cell differentiation

Researchers have spotted how specific proteins within the chromosomes of roundworms enable their offspring to produce specialized cells generations later, a startling finding that upends classical thinking that hereditary information for cell differentiation is mostly ingrained within DNA and other genetic factors.

7 Apr 2023

3D structure of a probable precursor to the CRISPR-Cas12 enzyme revealed

Gene editing is one of the latest breakthroughs in biology. The widely known CRISPR-Cas gene editing system provided prokaryotes (organisms that lack cell nuclei) an immunity against foreign DNA. Since the discovery of the CRISPR gene editing technology, scientists are revealing the evolution of the CRISPR-Cas proteins from their precursors.

7 Apr 2023

Mount Sinai to expand research training program in skin biology with support from $1.3 million T32 grant

The Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai will expand its research training program in skin biology with support from a five-year, $1.3 million T32 grant from the National Institutes of Health and the National Institute of Arthritis and Musculoskeletal and Skin Diseases.

3 Apr 2023

New type of nanoparticle can deliver messenger RNA encoding useful proteins to the lungs

Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins.

30 Mar 2023

NPC1L1-EGFP mice enable researchers to fluorescently visualize, evaluate vesicular endocytosis

Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is a well-established risk factor for atherosclerotic cardiovascular disease.

28 Mar 2023

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

A new UCLA-led study suggests that advanced genome editing technology could be used as a one-time treatment for the rare and deadly genetic disease CD3 delta severe combined immunodeficiency.

21 Mar 2023

Study focuses on new approach that delivers a "one-two punch" to help T cells attack solid tumors

A new approach that delivers a "one-two punch" to help T cells attack solid tumors is the focus of a preclinical study by researchers from the Perelman School of Medicine at the University of Pennsylvania.

15 Mar 2023

‘Glow-in-the-dark’ proteins could make disease diagnosis quicker and easier

Despite recent advancements, many highly sensitive diagnostic tests for viral diseases still require complicated techniques to prepare a sample or interpret a result, making them impractical for point-of-care settings or areas with few resources.

15 Mar 2023

New genetic animal model may inform potential therapeutic options for Down syndrome

National Institutes of Health researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be more similar to the changes seen in humans.

14 Mar 2023

Mutant mice models created for studying bipolar disorder

Bipolar disorder (BD) is a debilitating condition characterized by alternating states of depression (known as depressive episodes) and abnormal excitement or irritability (known as manic episodes).

7 Mar 2023

Common scientific method to analyze DNA in early human embryos fails to accurately reflect gene edits

A commonly used scientific method to analyze a tiny amount of DNA in early human embryos fails to accurately reflect gene edits, according to new research led by scientists at Oregon Health & Science University.

7 Mar 2023

Gene mutation capable of regulating pain discovered

Pain afflicts at least 1.5 billion people worldwide, and despite the availability of various painkilling drugs, not all forms of pain are treatable.

3 Mar 2023

Genome editing could help save rice crops threatened by climate change

A review of gene editing techniques suggests that the CRISPR/Cas (clustered regularly interspaced short palindromic repeats/Cas) method could be a possible 'savior' for rice crops threatened by climate change and high food demand.

3 Mar 2023

Genome editing techniques based on bacterial-artificial-chromosome in herpesvirus research

In a recent study published in the Microorganisms journal, researchers in China reviewed the uses of bacterial-artificial-chromosome (BAC)-based genome editing techniques in herpesvirus research.

28 Feb 2023

Study reveals new mechanism in the arms race between bacteria and viruses

UT Southwestern biochemist Zhijian "James" Chen, Ph.D., famously identified the cGAS enzyme pathway that alerts the human immune system to disease-causing invaders like viruses.