Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Study investigates the combined effects of aging and HIV-1 Tat expression in mice

A new research paper was published in Aging ("Aging (Albany NY)" by Medline/PubMed, "Aging-US" by Web of Science) Volume 14, Issue 13, entitled, "Age-related neuroendocrine, cognitive, and behavioral co-morbidities are promoted by HIV-1 Tat expression in male mice."

29 Jul 2022

Predicting viral antibody escape using pre-pandemic data

A new study reports early prediction of SARS-CoV-2 immune evasion using EVEscape.

28 Jul 2022

Icelandic study reveals how many children experience severe COVID symptoms

Researchers explore the incidence of SARS-CoV-2 infections in Icelandic children.

27 Jul 2022

Increased resistance to human interferons could be a potential driver of SARS-CoV-2 evolution

Researchers compared the potency of 17 human interferons (IFNs) against multiple SARS-CoV-2 variants.

27 Jul 2022

Scientists receive $3.9 million NIH grant to eradicate HIV from the brain

Finding a cure for HIV has been extremely difficult, in part because the virus hides from antiretroviral treatments in one of the hardest places to reach: the brain.

27 Jul 2022

Study estimates prevalence of SARS-CoV-2 omicron breakthrough infections in South Africa

Scientists have described the prevalence of vaccine breakthrough SARS-CoV-2 infection in South Africa during the period of delta and omicron circulation.

27 Jul 2022

Sixteen countries reported monkeypox virus infection in humans between April and June 2022

Researchers have analyzed the recent cases related to the monkeypox virus infection.

27 Jul 2022

Nasal spray highly effective against HIV and SARS-CoV-2 in animal models

The intranasal delivery of amph-protein vaccines is a potential approach to elicit a mucosal immune response against many infectious diseases.

26 Jul 2022

COVID vaccines induce memory B and T cells in primary antibody deficient patients

The SARS-CoV-2-specific B- and T-cell response post-COVID-19 primary and booster vaccination in primary antibody deficient patients.

20 Jul 2022

Study assesses eight de novo genome assembly software tools on viral next-generation sequencing data

A new study compares and assesses eight de novo genome assembly software tools on actual viral next-generation sequencing data.

20 Jul 2022

What is the association between natural killer cell dysfunction and COVID-19 disease severity?

Researchers assessed the association between natural killer cell dysfunction and COVID-19 disease severity.

20 Jul 2022

Researchers describe viral shedding of monkeypox virus in patients to better understand the possible role of different bodily fluids in disease transmission

Researchers described the shedding of the monkeypox (MPX) virus (MPXV) in Barcelona city of Spain.

20 Jul 2022

Should siRNA-based antivirals be added to the COVID toolbox?

A recent study reviewed the existing treatment modalities, including vaccines and antivirals, for SARS-CoV-2 infection.

19 Jul 2022

Researchers identify fusion peptide-specific monoclonal antibodies with broad neutralizing activity

Neutralizing mAbs identified in the current study sheds light on ACE2-triggered conformational change that restricts the immunogenicity of the highly conserved FP region.

14 Jul 2022

Clinical presentation of monkeypox infection in two Israeli males

Researchers described the symptomatology and clinical manifestations of monkeypox infections among two Israeli patients.

12 Jul 2022

Stinging nettle extract inhibits SARS-CoV-2 cell fusion

In a recent study posted to the bioRxiv* preprint server, researchers at Ghent University and KU Leuven, Belgium, demonstrated that Urtica dioica agglutinin (UDA), a monomeric lectin extracted from stinging nettle rhizomes, inhibited severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) cell to cell fusion.

12 Jul 2022

Study highlights need to prioritize immunocompromised COVID patients

In a recent Morbidity and Mortality Weekly Report (MMWR) published on the United States Center for Disease Control and Prevention (US-CDC) website, researchers evaluated whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected immunocompromised individuals are at a higher risk of intensive care unit (ICU) admission and death.

10 Jul 2022

Immunodeficiency News and Research

Further Reading

Study investigates the combined effects of aging and HIV-1 Tat expression in mice

Predicting viral antibody escape using pre-pandemic data

Icelandic study reveals how many children experience severe COVID symptoms

Increased resistance to human interferons could be a potential driver of SARS-CoV-2 evolution

Scientists receive $3.9 million NIH grant to eradicate HIV from the brain

Study estimates prevalence of SARS-CoV-2 omicron breakthrough infections in South Africa

Sixteen countries reported monkeypox virus infection in humans between April and June 2022

Nasal spray highly effective against HIV and SARS-CoV-2 in animal models

COVID vaccines induce memory B and T cells in primary antibody deficient patients

Study assesses eight de novo genome assembly software tools on viral next-generation sequencing data

What is the association between natural killer cell dysfunction and COVID-19 disease severity?

Researchers describe viral shedding of monkeypox virus in patients to better understand the possible role of different bodily fluids in disease transmission

Should siRNA-based antivirals be added to the COVID toolbox?

Researchers identify fusion peptide-specific monoclonal antibodies with broad neutralizing activity

Clinical presentation of monkeypox infection in two Israeli males

Stinging nettle extract inhibits SARS-CoV-2 cell fusion

Study highlights need to prioritize immunocompromised COVID patients

Scientists uncover how the innate immune system detects and fights HIV-1

Asymptomatic monkeypox infection detected from routine sexual health samples

2022 monkeypox presents with new symptoms

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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