Pancreatic Cancer News and Research

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Pancreatic cancer is the fourth leading cause of all cancer deaths in the United States and the third leading cause of cancer deaths in individuals ages 40 to 60. Approximately 37,000 Americans are diagnosed with pancreatic cancer each year, and, each year, approximately the same number die from it. Often, pancreatic cancer is found too late for surgical intervention, and chemotherapy and radiation treatments have little effect.

Single-cell RNA sequencing provides new insights into gastric cancer

A new study led by researchers at The University of Texas MD Anderson Cancer Center provides a deeper understanding of the evolution of the tumor microenvironment during gastric cancer progression.

6 Jul 2023

Study identifies role of ROR1 in pancreatic cancer metastasis

Tumor-initiating cells, or cancer stem cells, are gaining attention in cancer therapy, as they can travel through the body and cause cancerous tumors at other sites through metastasis.

5 Jul 2023

Staging laparoscopy enables early detection of pancreatic cancer: Study

A study published in the Journal of the American College of Surgeons reveals that performing a minor surgical procedure on patients newly diagnosed with pancreatic cancer helps to identify cancer spread early and determine the stage of cancer

30 Jun 2023

WHO to declare artificial sweetener aspartame as possible carcinogen

The World Health Organization recently indicated that aspartame will likely be declared a “possible carcinogen to humans.”

29 Jun 2023

Novel drug combination shows promise in treating pancreatic cancer

Mutations in the KRAS gene are the major driver of pancreatic cancer. The resulting protein controls multiple signaling pathways involved in cell growth and survival. In cancer, the gene is mutated to be permanently "on," driving cells to excessively multiply and form tumors.

28 Jun 2023

New kidney cancer model highlights molecular targets and genomic events that drive metastasis

Researchers at The University of Texas MD Anderson Cancer have engineered a new model of aggressive renal cell carcinoma (RCC), highlighting molecular targets and genomic events that trigger chromosomal instability and drive metastatic progression.

26 Jun 2023

$3.3M HHS grant supports UTHealth Houston study on combination treatment strategy for pancreatic cancer

A combination strategy of endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) with chemotherapy for pancreatic cancer will be studied at UTHealth Houston through a $3.3 million grant from the National Cancer Institute by the U.S. Department of Health and Human Services.

20 Jun 2023

Using ultrasound for an effective sonodynamic treatment of orthotopic pancreatic cancer

Ultrasound is a promising technique for treating cancer. Unlike laser light, used in photodynamic cancer therapy, ultrasound waves can reach deep into tissue - up to 12 cm - to treat deep tumors without damaging healthy cells.

14 Jun 2023

What was the prevalence of germline genetic testing among patients diagnosed with cancer in California and Georgia between 2013 and 2019?

Researchers performed an observational study to determine the prevalence of germline genetic testing among all patients aged 20 years or older diagnosed with cancer between January 1, 2013, and March 31, 2019, in two United States, California and Georgia.

8 Jun 2023

Promising targeted therapy offers new hope to certain patients with advanced pancreatic cancer

A promising new targeted cancer therapy will soon be available to certain patients with advanced pancreatic cancer – from the comfort of their home.

7 Jun 2023

Umbrella review assesses the association between artificially sweetened beverages and health outcomes

A recent umbrella review evaluated the associations between ASBs and health outcomes.

6 Jun 2023

Clinical trials demonstrate positive results from targeted therapy for patients with multiple tumor types with FGFR alterations

Three clinical trials led by researchers at The University of Texas MD Anderson Cancer Center demonstrated positive results from the targeted therapy erdafitinib for patients with multiple tumor types harboring FGFR alterations.

5 Jun 2023

Tumors in distant organs remotely reprogram the liver

Cancers often release molecules into the bloodstream that pathologically alter the liver, shifting it to an inflammatory state, causing fat buildup and impairing its normal detoxifying functions, according to a study from investigators at Weill Cornell Medicine.

25 May 2023

New method can kill aggressive brain tumors

Researchers at the University of Gothenburg, working with French colleagues, have successfully developed a method able to kill the aggressive brain tumor glioblastoma.

25 May 2023

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Research unveils the significance of uridine as a metabolic fuel in pancreatic ductal adenocarcinoma (PDA) cells under glucose-deprived conditions. Uridine utilization, mediated by uridine phosphorylase 1 (UPP1), supports redox balance, survival, and proliferation in PDA, highlighting its potential as a novel therapeutic target in the treatment of this resistant cancer.

23 May 2023

The role of RNA splicing in one of the deadliest forms of pancreatic cancer

In this interview, we spoke to Adrian Krainer, a Professor at Cold Spring Harbor Laboratory, about his latest research into the role of RNA splicing in one of the deadliest forms of pancreatic cancer.

22 May 2023

Clinical trial tests effectiveness of chemotherapy after surgery for pancreatic neuroendocrine tumors

A new clinical trial is testing the effectiveness of chemotherapy treatment following surgery for a subset of pancreatic cancer patients.

19 May 2023

New liquid biopsy tool shows 30% increased sensitivity in detecting ctDNA

Pancreatic cancer is the seventh leading cause of cancer death worldwide and despite the increasing incidence of this disease, effective treatments are lacking and prognosis for patients with this tumor type remains poor, with approximately 70% of patients dying within one year of diagnosis.

16 May 2023

Study establishes a mechanistic link between obesity and oral cancer immune escape

A team from the University of Michigan Rogel Cancer Center and School of Dentistry, led by Yu Leo Lei, D.D.S., Ph.D., have identified a mechanism in mice for how obesity affects some oral cancers' ability to escape from the immune system.

16 May 2023

Break Through Cancer funds AML research at MD Anderson

The University of Texas MD Anderson Cancer Center was awarded more than $5.7 million in grants from Break Through Cancer to support collaborative research teams working to discover novel molecular targets to eradicate minimal residual disease in acute myeloid leukemia (AML) and to treat clonal hematopoiesis, a precursor to AML.

16 May 2023

Pancreatic Cancer News and Research

Further Reading

Single-cell RNA sequencing provides new insights into gastric cancer

Study identifies role of ROR1 in pancreatic cancer metastasis

Staging laparoscopy enables early detection of pancreatic cancer: Study

WHO to declare artificial sweetener aspartame as possible carcinogen

Novel drug combination shows promise in treating pancreatic cancer

New kidney cancer model highlights molecular targets and genomic events that drive metastasis

$3.3M HHS grant supports UTHealth Houston study on combination treatment strategy for pancreatic cancer

Using ultrasound for an effective sonodynamic treatment of orthotopic pancreatic cancer

What was the prevalence of germline genetic testing among patients diagnosed with cancer in California and Georgia between 2013 and 2019?

Promising targeted therapy offers new hope to certain patients with advanced pancreatic cancer

Umbrella review assesses the association between artificially sweetened beverages and health outcomes

Clinical trials demonstrate positive results from targeted therapy for patients with multiple tumor types with FGFR alterations

Tumors in distant organs remotely reprogram the liver

New method can kill aggressive brain tumors

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

The role of RNA splicing in one of the deadliest forms of pancreatic cancer

Clinical trial tests effectiveness of chemotherapy after surgery for pancreatic neuroendocrine tumors

New liquid biopsy tool shows 30% increased sensitivity in detecting ctDNA

Study establishes a mechanistic link between obesity and oral cancer immune escape

Break Through Cancer funds AML research at MD Anderson

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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