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International travel and health care networks drive Candida auris outbreaks

In just a decade, the drug-resistant fungal pathogen Candida auris (C. auris) has emerged as one of the most formidable threats to health care settings worldwide.

10 Feb 2025

AI-based technology accelerates discovery of new tuberculosis drug candidates

Tuberculosis is a serious global health threat that infected more than 10 million people in 2022. Spread through the air and into the lungs, the pathogen that causes "TB" can lead to chronic cough, chest pains, fatigue, fever and weight loss.

7 Feb 2025

Urban density and HIV prevalence linked to rising antibiotic resistance in gonorrhea

Researchers identify key geographic and health factors that may predict the prevalence of antimicrobial-resistant gonorrhea in the United States.

7 Feb 2025

How lymphoid tissues protect against viral infections

Researchers explore the cellular and molecular adaptations associated with human secondary lymphoid tissue in adults during viral infection.

7 Feb 2025

Researchers create random versions of human genomes to study disease

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.

31 Jan 2025

Climate change is pushing up rates of kidney disease and urological cancers

Climate change is increasing the risk of urological diseases, including cancer and kidney conditions, while urological healthcare itself contributes to environmental harm through high carbon emissions.

29 Jan 2025

New tool launched to track infectious disease spread through wastewater

The European Commission has just launched a new tool that supports the tracking of the spread of infectious diseases by analyzing wastewater: the European Wastewater Surveillance Dashboard. It displays data from across the EU by bringing together existing national and research-based dashboards.

29 Jan 2025

Led by RFK Jr., conservatives embrace raw milk. Regulators say it's dangerous.

In summertime, cows wait under a canopy to be milked at Mark McAfee's farm in Fresno, California. From his Cessna 210 Centurion propeller plane, the 63-year-old can view grazing lands of the dairy company he runs that produces products such as unpasteurized milk and cheese for almost 2,000 stores.

29 Jan 2025

New compound V-161 offers hope in the fight against antibiotic-resistant bacteria

V-161, a novel compound targeting the Na+ -V-ATPase enzyme in vancomycin-resistant Enterococcus faecium (VRE), significantly reduces bacterial growth and colonization.

23 Jan 2025

EU-funded Vigilant network aims to develop broad-spectrum antiviral drugs

Pandemics threaten both human health and the global economy. Vaccines are an essential part of the fight against pandemics, but they are only available months after the outbreak

23 Jan 2025

Researchers map genetic differences across children with Wilms tumor

Genetically tailored treatment plans for children with a type of kidney cancer could help provide the most effective care while minimizing side effects as much as possible.

23 Jan 2025

Researchers discover how location affects immune cells' role in fighting disease

The human immune system is like an army of specialized soldiers (immune cells) each with a unique role to play in fighting disease.

22 Jan 2025

Study reveals how gut bacteria influence immune cell training and inflammation

A study led by David Sancho at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid reveals how an increase in intestinal permeability allows the natural gut bacteria to cross the intestinal barrier and reach the bone marrow, where they induce epigenetic changes-modifications that alter gene activity without affecting DNA sequence-in the stem cells that give rise to immune cells.

22 Jan 2025

New EU project aims to advance pandemic preparedness

With viral disease emergence expected to accelerate, preparing for possible future pandemics is paramount.

21 Jan 2025

Breakthrough study maps critical structure of Nipah virus polymerase

Scientists at Harvard Medical School and Boston University Chobanian & Avedisian School of Medicine have mapped a critical component of the Nipah virus, a highly lethal bat-borne pathogen that has caused outbreaks in humans almost every year since it was identified in 1999.

20 Jan 2025

The diverse immunological functions of megakaryocytes

Megakaryocytes (MKs), known for their role in platelet production, have emerged as critical players in immune responses, showcasing versatility in both physiological and pathological contexts.

17 Jan 2025

New research identifies metabolic targets to combat antibiotic-resistant bacterial infections

Targeting unique metabolic pathways in pathogens offers a novel approach to precision antibiotics, addressing the growing challenge of antimicrobial resistance.

17 Jan 2025

Study reveals high prevalence of Lyme disease bacteria in Northeast ticks

Across most of the Northeast, getting bitten by a blacklegged tick- also called a deer tick - is a risk during spring, summer, and fall. A new Dartmouth study, published in Parasites and Vectors, finds that 50% of adult blacklegged ticks carry the bacteria that causes Lyme disease while 20% to 25% of the younger (nymph) blacklegged ticks carry the bacteria.

17 Jan 2025

Study uncovers why lupus patients have weaker response to COVID-19 vaccines

A recent study by Emory University researchers provides new insights into why the mRNA vaccines developed to fight COVID-19 in 2021 are less effective in patients with autoimmune diseases.

16 Jan 2025

Groundbreaking trial finds levofloxacin effective against multidrug-resistant TB

A clinical trial published in the New England Journal of Medicine showed that the oral antibiotic levofloxacin taken once-daily for six months substantially reduced the risk of developing drug-resistant tuberculosis (TB), and almost halved adults' and children's risk of developing multidrug-resistant TB.

15 Jan 2025