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Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems. Most aspects of human physiology are closely homologous to corresponding aspects of animal physiology, and animal experimentation has provided much of the foundation of physiological knowledge. Anatomy and physiology are closely related fields of study: anatomy, the study of form, and physiology, the study of function, are intrinsically tied and are studied in tandem as part of a medical curriculum.

New biomarker may be the first specific and quantifiable indicator for confirming long COVID

Researchers from the Translational Genomics Research Institute (TGen), part of City of Hope, and the Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center have identified a potential biomarker for long COVID.

11 Aug 2025

Lithium deficiency emerges as a hidden driver of Alzheimer’s

What is the earliest spark that ignites the memory-robbing march of Alzheimer’s disease? Why do some people with Alzheimer’s-like changes in the brain never go on to develop dementia? These questions have bedeviled neuroscientists for decades.

8 Aug 2025

Study links epigenetic markers to cardiovascular risk in type 2 diabetes

People with type 2 diabetes are up to four times more likely to have heart attacks, strokes, anginas and other coronary heart diseases than healthy people.

7 Aug 2025

Heart cells adapt and stretch to shape a healthy beating heart

Researchers at the Francis Crick Institute have discovered that the heart's own contractions trigger biological signals that guide the formation of a functional beating heart.

6 Aug 2025

Nighttime caffeine linked to increased impulsivity

Do you find yourself reaching for a cup of coffee at night to stay alert? A new study from The University of Texas at El Paso suggests you might want to reconsider.

5 Aug 2025

Weight loss with ozempic may weaken muscles even when size remains stable

As use of the popular anti-diabetic and weight-loss drug Ozempic skyrockets, so have concerns about the medication's side effects.

5 Aug 2025

Scaling organ‑chip technology for human‑relevant drug discovery

Discover how AVA brings scale and reproducibility to organ‑chip technology, enabling human‑relevant insights that accelerate drug discovery workflows.

From Emulate, Inc. 5 Aug 2025

Natural brain rhythms control stress hormone levels and alertness

Ōtākou Whakaihu Waka-led research has found stress-controlling brain cells switch on and off in a steady rhythm about once every hour – even when nothing stressful is happening.

4 Aug 2025

Editorial emphasizes the critical role of heart-lung interactions in pulmonary vascular disease

A new editorial published in Comprehensive Physiology underscores the critical importance of understanding heart-lung interactions in pulmonary vascular disease (PVD).

4 Aug 2025

New research reveals why fiber-rich diets fuel you better than refined foods

This study quantifies how much energy the human body harvests from gut microbial fermentation of dietary fiber, integrating bacterial physiology, diet, and metagenomic data. Results reveal that dietary fiber, not microbiome composition, mainly determines the amount of short-chain fatty acids absorbed, impacting daily energy and metabolic health.

31 Jul 2025

Saliva testing offers a non-invasive way to detect early metabolic risk

Measuring elevated levels of insulin in blood, called hyperinsulinemia, is a proven way to measure metabolic health and can show risk of developing future health concerns, including Type 2 diabetes, obesity and heart disease.

31 Jul 2025

Canadian scientists trap gut microbe fuel to improve blood sugar and liver health

A team of Canadian scientists has discovered a surprising new way to improve blood sugar levels and reduce liver damage: by trapping a little-known fuel made by gut bacteria before they wreak havoc on the body.

30 Jul 2025

New strategy reveals how mannose receptor helps regulate blood proteins

The amount of each of the more than a thousand different glycoproteins in your blood varies widely with the 10 most abundant glycoproteins accounting for 90 percent of the total mass.

30 Jul 2025

Plant-based agent inhibits key protein to reduce bronchial thickening

A plant-based agent inhibits a protein that, among other things, is responsible for the dreaded thickening of the bronchial wall.

29 Jul 2025

New software predicts cancer cell behavior to advance treatment

In the same vein as weather forecast models that predict developing storms, researchers now have developed a method to predict the cell activity in tissues over time.

28 Jul 2025

Low-gluten diets disrupt gut health by depleting key bacteria

Long-term gluten reduction may disrupt gut microbiota balance, reducing beneficial bacteria and increasing ethanol, linked to inflammation and metabolic risks.

24 Jul 2025

Neurons shift during repeated navigation of identical paths

In a new study, Northwestern University neurobiologists found the brain's internal GPS changes each time we navigate a familiar, static environment.

23 Jul 2025

Mitochondrial protein misfolding found to kill pancreatic cells in type 2 diabetes

Aging-related diseases, including cancer, cardiovascular disorders and type 2 diabetes, are associated with defects in protein synthesis and folding.

22 Jul 2025

Global experts release guidance on CT imaging for post-COVID lung abnormalities

Experts representing multiple societies and institutions across 14 countries have published guidance for computed tomography (CT) imaging in patients with residual lung abnormalities after COVID-19 illness.

22 Jul 2025

New imaging technique reveals how cells organize glucose processing

In a scientific first, researchers from Vanderbilt University and the University of California, San Diego, have generated a high-resolution metabolic "map" of how cells orchestrate glucose processing, revealing a hidden world where organelles and molecular complexes collaborate when responding to a rush of nutrients.

22 Jul 2025