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Simple algorithm may help reduce treatment disparities in multiple sclerosis

A simple treatment algorithm may help reduce treatment disparities for Hispanic and Black people with multiple sclerosis (MS), according to a preliminary study released today, March 3, 2025, that will be presented at the American Academy of Neurology's 77th Annual Meeting taking place April 5–9, 2025, in San Diego and online.

3 Mar 2025

Non-invasive 40Hz gamma stimulation could help fight Alzheimer’s

A decade after scientists in The Picower Institute for Learning and Memory at MIT first began testing whether sensory stimulation of the brain's 40Hz "gamma" frequency rhythms could treat Alzheimer's disease in mice, a growing evidence base supporting the idea that it can improve brain health-in humans as well as animals-has emerged from the work of labs all over the world.

3 Mar 2025

Stress granules as potential biomarkers for neurodegenerative diseases

Stress granules (SGs) are transient organelles that form when cells experience stress, serving as critical hubs for RNA metabolism and cellular survival.

3 Mar 2025

Early CPAP treatment may reduce Parkinson's disease risk in people with sleep apnea

People with obstructive sleep apnea have an increased risk of Parkinson's disease, but if started early enough, continuous positive airway pressure (CPAP) may reduce that risk, according to a preliminary study released today, March 2, 2025, that will be presented at the American Academy of Neurology's 77th Annual Meeting taking place April 5–9, 2025, in San Diego and online.

2 Mar 2025

New brain map reveals insights into multiple sclerosis development

NIH study reveals key players underlying disease onset and repair.

27 Feb 2025

Nasal spray may offer new hope for traumatic brain injury patients

A new study led by researchers at Mass General Brigham suggests a nasal spray developed to target neuroinflammation could one day be an effective treatment for traumatic brain injury (TBI).

27 Feb 2025

Drug may offer new hope for preventing migraines in kids and teens

For children and teens living with migraine, there may be a new preventive treatment, according to a preliminary study released today, February 26, 2025, that will be presented at the American Academy of Neurology's 77th Annual Meeting taking place April 5–9, 2025, in San Diego and online.

26 Feb 2025

New study identifies effective blood tests for ALS diagnosis and monitoring

ALS, or amyotrophic lateral sclerosis, can sometimes be difficult to diagnose or to predict how quickly the disease is likely to progress. A new study helps determine which blood tests are best at identifying and monitoring ALS.

26 Feb 2025

LMU study uncovers dual functionality of dendritic cells in immune response

LMU researchers have shown that a particular type of immune cell acts more flexibly than previously thought - with potential for new therapeutic approaches.

26 Feb 2025

Lean and oily fish consumption linked to slower disability progression in MS

A high dietary intake of lean and oily fish may slow the progression of disability in people with multiple sclerosis (MS), suggests a comparative population based study, published online in the Journal of Neurology Neurosurgery & Psychiatry.

25 Feb 2025

Exploring how 25-hydroxycholesterol triggers ferroptosis in glial cells

Oxysterols are a class of molecules derived from cholesterol via oxidation or as byproducts of cholesterol synthesis.

20 Feb 2025

New approach shows promise for treating fragile X syndrome

Building on more than two decades of research, a study by MIT neuroscientists at The Picower Institute for Learning and Memory reports a new way to treat pathology and symptoms of fragile X syndrome, the most common genetically-caused autism spectrum disorder.

20 Feb 2025

Smoking linked to unexplained strokes in younger adults

Smoking, particularly heavy smoking, is linked to some unexplained strokes in younger adults, mainly in male individuals and in people ages 45 to 49, according to a study published in the February 19, 2025, online issue of Neurology Open Access, an official journal of the American Academy of Neurology.

20 Feb 2025

New therapeutic cocktails show promise for long-lasting asthma relief

Current asthma treatments don't work in all patients, and they don't provide long-term relief from potentially deadly asthma attacks.

19 Feb 2025

Study shows rapid transformation in multiple sclerosis treatment in Finland

A registry study led by the University of Oulu examined the early-stage treatment of relapsing-remitting multiple sclerosis (MS) in Finland between 2013 and 2022.

19 Feb 2025

Study shows promise for new treatment approach for multiple sclerosis

A sponge-like implant in mice helped guide a treatment that slowed or stopped a degenerative condition similar to multiple sclerosis in humans. It also gave University of Michigan researchers a first look at how primary progressive multiple sclerosis, the fastest-progressing version of the disease, attacks the central nervous system early on.

19 Feb 2025

Researchers identify MLC1 as potential target in multiple sclerosis

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system caused by the immune system. B cells, which are a type of white blood cell, play a role in the development of MS and are thus a target for therapies.

18 Feb 2025

New review maps the impact of reproductive hormones on neurological health

A comprehensive review published today in Brain Medicine by leading neuroendocrinologist Professor Hyman M. Schipper from McGill University's Department of Neurology and Neurosurgery maps out the extensive influence of reproductive hormones on neurological health and disease.

18 Feb 2025

First insights into familial ALS in Egypt reveal genetic variations and disease progression

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the progressive degeneration of motor neurons, leading to muscle weakness and eventually death.

18 Feb 2025

Groundbreaking ALS platform trial accelerates research and drug testing

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with few treatment options. Since 2018, the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system, has been working with national and international stakeholders to accelerate ALS research by launching the first platform trial in ALS to simultaneously test multiple drugs using shared trial infrastructure and placebo data.

17 Feb 2025