Structural Biology News and Research

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New class of molecules could someday become basis for Zika-specific therapeutic

The Zika virus is widely known for causing microcephaly and other brain defects in the fetuses of pregnant, infected women.

4 Apr 2019

Researchers unravel 3D structure of key molecular target for cancer treatment

Columbia University scientists, in collaboration with researchers from Nimbus Therapeutics, have demystified a metabolic enzyme that could be the next major molecular target in cancer treatment.

4 Apr 2019

Scientists develop new accurate computational method to enhance drug target stability

Scientists from the Moscow Institute of Physics and Technology, the Skolkovo Institute of Science and Technology, and the University of Southern California have developed a new computational method for the design of thermally stable G protein-coupled receptors that are of great help in creating new drugs.

30 Mar 2019

Study uncovers potential new strategy to treat influenza A

A team of researchers from Scripps Research and Janssen Research & Development LLC has discovered an orally active small molecule that neutralizes influenza A group 1 viruses, the most common flu strains.

11 Mar 2019

Researchers develop method for rapidly measuring proteins' unique vibrations

In the cells of every living organism -- humans, birds, bees, roses and even bacteria -- proteins vibrate with microscopic motions that help them perform vital tasks ranging from cell repair to photosynthesis.

5 Mar 2019

Research reveals how metabolites can be used to inhibit epigenetic mechanisms and treat MS

Understanding and mitigating the role of epigenetics (environmental influences that trigger changes in gene expression) in disease development is a major goal of researchers.

28 Feb 2019

Structure of human type 2 cannabinoid receptor revealed

A Chinese research team joined forces with Russian and U.S. biologists to obtain the crystal structure of the human type 2 cannabinoid receptor.

28 Feb 2019

UVA scientist receives $1 million award to map out submicroscopic world

A scientist at the University of Virginia School of Medicine has received a prestigious three-year, $1 million award from the William M. Keck Foundation to develop a new and better way to map out the submicroscopic world.

22 Feb 2019

New design guidance could advance development of disease-sensing nanomaterials

Scientists have long sought to develop drug therapies that can more precisely diagnose, target and effectively treat life-threatening illness such as cancer, cardiovascular and autoimmune diseases.

22 Feb 2019

Johns Hopkins scientists find new compound that may prevent reperfusion injury

In a strategic search, Johns Hopkins scientists created and screened a library of 45,000 new compounds containing chemical elements of widely used immune system suppressants, and say they found one that may prevent reperfusion injury, a tissue-damaging and common complication of surgery, heart attack and stroke.

21 Feb 2019

Scientists join forces to identify a new approach to fight African sleeping sickness

Scientists working in a range of disciplines joined forces to identify a new approach to combat African sleeping sickness. Fundamental research undertaken under the supervision of Professor Ute Hellmich of Johannes Gutenberg University Mainz has revealed a promising strategy to develop a suitable agent.

20 Feb 2019

Researchers identify suicide toxin in the bacteria responsible for tuberculosis

The bacteria responsible for tuberculosis can be killed by a toxin they produce unless it is neutralized by an antidote protein. The European team of scientists behind this discovery is coordinated by researchers from the Institute of Pharmacology and Structural Biology and the European Molecular Biology Laboratory.

18 Feb 2019