Immune System News and Research

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Memory B cells can be localized in the lungs, research shows

How can we increase the efficacy of vaccines used to protect against viral respiratory diseases such as influenza and COVID-19? Scientists from Inserm, CNRS and Aix-Marseille Université at the Center of Immunology Marseille-Luminy are opening up new prospects in the field, with the triggering of memory B cells directly in the lungs looking to be a promising avenue.

28 Jun 2022

New study looks at the role of beta cells in triggering autoimmunity

Research into the causes of type 1 diabetes often focuses on the autoimmune response, where the immune system destroys pancreatic islet beta cells that produce insulin.

28 Jun 2022

Analysis finds variation in the management of mantle cell lymphoma across clinical settings

There is considerable variation in the management of mantle cell lymphoma across different clinical settings, and some strategies do not always conform with what might be expected, according to an analysis by investigators from Weill Cornell Medicine and other leading health institutions.

28 Jun 2022

Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

In a recent study posted to the bioRxiv* pre-print server, researchers in the United States described a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal antibody (mAb) SP1-77 that broadly neutralized its multiple variants of concern (VOCs).

28 Jun 2022

Healthy Black and Hispanic adolescents found to have low vitamin D levels

Results from a University of Houston College of Nursing study indicate that 61% of otherwise healthy Black and Hispanic adolescents have low vitamin D levels, that drop even lower with age.

28 Jun 2022

Scientists discover how to prevent T cell exhaustion to maintain the fight against cancer

When faced with a formidable foe for months on end, the immune system's T cells begin to tire. Whether fighting a cancer or a chronic infection, they become less effective over time, a phenomenon dubbed "T cell exhaustion" by scientists.

28 Jun 2022

Phase 1 clinical trial of new influenza vaccine begins at NIH Clinical Center in Bethesda

A Phase 1 clinical trial of a novel influenza vaccine has begun inoculating healthy adult volunteers at the National Institutes of Health Clinical Center in Bethesda, Maryland.

28 Jun 2022

Study identifies a new mechanism that explains how immune cells learn to discern friend from foe

The human immune system is a nearly perfect defense mechanism. It protects the body from disease-causing bacteria, viruses, and other pathogens. It detects nascent tumors and eradicates them. It cleans up cellular debris at the site of injury or infection.

28 Jun 2022

Mother's gut microbes can aid in the healthy development of baby, finds study

Researchers studying mice have found the first evidence of how a mother's gut microbes can help in the development of the placenta, and the healthy growth of the baby.

28 Jun 2022

Highly antibiotic-resistant strain of MRSA on pigs is capable of rapidly adapting to human hosts

A new study has found that a highly antibiotic-resistant strain of the superbug MRSA – methicillin resistant Staphylococcus aureus – has emerged in livestock in the last 50 years, probably due to widespread antibiotic use in pig farming.

28 Jun 2022

Researchers identify an epigenetic signature associated to the development of MIS-C after COVID-19

Researchers from the Cancer Epigenetics group led by Dr. Manel Esteller at the Josep Carreras Leukaemia Research Institute and Dr. Aurora Pujol, from the Bellvitge Biomedical Research Institute, have identified an epigenetic signature associated to the development of the Multisystem Inflammatory Syndrome in Children (MIS-C) after a SARS-CoV-2 virus infection.

27 Jun 2022

Chemically modified rocaglates have a stronger effect against viral replication

Hepatitis E virus (HEV) is widespread, and so far there is no effective drug. In the search for one, the so-called rocaglates have come into focus: plant compounds that can inhibit the replication of viruses.

27 Jun 2022

A full model of the SARS-CoV-2 spike protein for studying its atomic-level dynamics by multiple microsecond simulations

Researchers constructed a full-length SARS-CoV-2 spike structure in its membrane-bound state to study functionally relevant aspects of its global conformational dynamics.

27 Jun 2022

Antibody profiles of internal viral proteins predict severe COVID-19 outcomes

Most research on immunity to the SARS-CoV-2 virus and COVID-19 vaccine development has focused on antibody responses to the spike protein and other viral surface proteins.

24 Jun 2022

Study underscores the strong protective effect of flu vaccine against Alzheimer's disease

People who received at least one influenza vaccine were 40% less likely than their non-vaccinated peers to develop Alzheimer's disease over the course of four years, according to a new study from UTHealth Houston.

24 Jun 2022

Nearly all known biological pathways in the brain are linked to Alzheimer's disease

Nearly six million older adults have Alzheimer's disease in the United States, a number expected to double by 2050.

24 Jun 2022

New nanoparticles effectively stopped the growth and spread of ovarian, liver tumors in mice

As they grow, solid tumors surround themselves with a thick, hard-to-penetrate wall of molecular defenses. Getting drugs past that barricade is notoriously difficult.

24 Jun 2022

New funding to help advance scientific understanding of skin disorders in children and young people

For children and young people, skin disorders can have a devastating impact on physical and mental wellbeing, yet effective treatments are few and far between.

23 Jun 2022

Listeria-based booster vaccine strategy offers improved protection against recurrent colorectal cancer

Colorectal, pancreatic, esophageal and stomach cancers - some of the deadliest kinds of cancer - have high recurrence rates where the cancer comes back even after successful surgery or radiation treatment.

23 Jun 2022

Addressing parents' hesitancy to vaccinate their children against COVID

Researchers examine notable risk factors related to vaccine hesitancy among parents.

23 Jun 2022

Immune System News and Research

Memory B cells can be localized in the lungs, research shows

New study looks at the role of beta cells in triggering autoimmunity

Analysis finds variation in the management of mantle cell lymphoma across clinical settings

Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

Healthy Black and Hispanic adolescents found to have low vitamin D levels

Scientists discover how to prevent T cell exhaustion to maintain the fight against cancer

Phase 1 clinical trial of new influenza vaccine begins at NIH Clinical Center in Bethesda

Study identifies a new mechanism that explains how immune cells learn to discern friend from foe

Mother's gut microbes can aid in the healthy development of baby, finds study

Highly antibiotic-resistant strain of MRSA on pigs is capable of rapidly adapting to human hosts

Researchers identify an epigenetic signature associated to the development of MIS-C after COVID-19

Chemically modified rocaglates have a stronger effect against viral replication

A full model of the SARS-CoV-2 spike protein for studying its atomic-level dynamics by multiple microsecond simulations

Antibody profiles of internal viral proteins predict severe COVID-19 outcomes

Study underscores the strong protective effect of flu vaccine against Alzheimer's disease

Nearly all known biological pathways in the brain are linked to Alzheimer's disease

New nanoparticles effectively stopped the growth and spread of ovarian, liver tumors in mice

New funding to help advance scientific understanding of skin disorders in children and young people

Listeria-based booster vaccine strategy offers improved protection against recurrent colorectal cancer

Addressing parents' hesitancy to vaccinate their children against COVID

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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