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Study detects key differences in immune responses of adults and children with COVID-19

The first study comparing the immune responses of adults and children with COVID-19 has detected key differences that may contribute to understanding why children usually have milder disease than adults.

22 Sep 2020

Targeted therapy improves disease-free survival in patients with early-stage NSCLC

According to updated findings led by researchers at Yale Cancer Center, treatment with the targeted therapy osimertinib following surgery continues to significantly improve disease-free survival (DFS) in patients with early-stage, non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) gene mutations.

21 Sep 2020

Genomic adaptations to rice‐based diets contribute to mitigation of metabolic risk

The traditional rice-based diet of some east-Asian population has brought to a number of genomic adaptations that may contribute to mitigating the spread of diabetes and obesity.

21 Sep 2020

Providing personalized care for bleeding disorders

An interview with Dr. Carmen Escuriola-Ettingshausen MD, Mörfelden-Walldorf, Germany on providing personalized care for bleeding disorders.

From Takeda 21 Sep 2020

Providing personalized care for bleeding disorders

An interview with Dr. Carmen Escuriola-Ettingshausen MD, Mörfelden-Walldorf, Germany on providing personalized care for bleeding disorders.

From Takeda 21 Sep 2020

Adding abemaciclib to hormonal therapy reduces recurrence in patients with HR+ HER2- early breast cancer

Adding abemaciclib to hormonal therapy reduces the risk of cancer recurrence by 25% in patients with high-risk early hormone receptor positive (HR+) human epidermal growth factor receptor 2 negative (HER2-) breast cancer, according to results from a study at ESMO 2020.

21 Sep 2020

New polygenic risk score to help predict the odds of drugs causing liver damage

The ancient Romans studied the livers of sacrificial animals to read omens and make prophesies. Now researchers at Tokyo Medical and Dental University and Takeda-CiRA program along with a world-wide team of collaborators, have devised a polygenic risk score (PRS) based on liver genomics that can predict the likelihood of medications causing liver damage.

19 Sep 2020

Trial shows new first-line treatment option for patients with metastatic kidney cancer

The results of the phase 3 CheckMate 9ER trial have provided a new first-line treatment option for patients with metastatic kidney cancer. The late breaking results are presented at ESMO 2020.

19 Sep 2020

High fructose corn syrup increases risk factors for heart disease, diabetes

Consuming high fructose corn syrup appears to be as bad for your health as consuming sugar in the form of fructose alone, according to a new study from researchers at the University of California, Davis.

18 Sep 2020

Study finds wide variation in levels and anti-tumor effectiveness of a common cancer drug

When used to manage infections, the drug itraconazole is generally given at a single, fixed dose to all patients.

17 Sep 2020

Glucagon resistance: A new biological concept in the fight against diabetes

Researchers from the University of Copenhagen are introducing a new biological concept in the fight against diabetes: glucagon resistance.

17 Sep 2020

CNIC researchers uncover a mechanism explaining how macrophages regulate obesity

Macrophages are immune system cells. They are essential in the early response to infections, and they also have a key role in the proper functioning of our tissues and the regulation of obesity.

17 Sep 2020

Breakthrough discovery could turn cancer into a treatable disease

Professor Michael Lisanti and Professor Federica Sotgia have made a discovery that could turn cancer into a treatable disease and remove the fear from a cancer diagnosis.

16 Sep 2020

Study uncovers new markers present on melanoma tumors

A collaborative study led by Monash University's Biomedicine Discovery Institute and the Olivia Newton-John Cancer Research Institute has uncovered new markers (HLA-associated peptides) that are uniquely present on melanoma tumours and could pave the way for therapeutic vaccines to be developed in the fight against melanoma.

16 Sep 2020

Study provides valuable insights on effects of APOE gene on health and disease

From Alzheimer's to obesity, life can change dramatically if you discover you have a genetic risk of disease. Now, a new study from the Australian Centre for Precision Health, University of South Australia is challenging these predispositions, showing that some of the genes traditionally labelled as 'bad' are not always what they seem.

16 Sep 2020

Researchers are testing the effectiveness of multiple treatments to prevent COVID-19

A study on the effectiveness of multiple treatments, including laboratory-made antibodies, at preventing mild COVID-19 from advancing to severe illness in the outpatient setting is underway by researchers at The University of Texas Health Science Center at Houston (UTHealth).

16 Sep 2020

Identifying, preventing and treating drug-induced arrhythmias

Health care professionals should become more familiar with medications that cause irregular heart rhythms called arrhythmias, according to "Drug- Induced Arrhythmias," a new scientific statement from the American Heart Association, published today in the Association's flagship journal Circulation.

15 Sep 2020

Liver News and Research

Study detects key differences in immune responses of adults and children with COVID-19

Targeted therapy improves disease-free survival in patients with early-stage NSCLC

Genomic adaptations to rice‐based diets contribute to mitigation of metabolic risk

Providing personalized care for bleeding disorders

Providing personalized care for bleeding disorders

Adding abemaciclib to hormonal therapy reduces recurrence in patients with HR+ HER2- early breast cancer

New polygenic risk score to help predict the odds of drugs causing liver damage

Trial shows new first-line treatment option for patients with metastatic kidney cancer

High fructose corn syrup increases risk factors for heart disease, diabetes

Study finds wide variation in levels and anti-tumor effectiveness of a common cancer drug

Glucagon resistance: A new biological concept in the fight against diabetes

CNIC researchers uncover a mechanism explaining how macrophages regulate obesity

Breakthrough discovery could turn cancer into a treatable disease

Study uncovers new markers present on melanoma tumors

Study provides valuable insights on effects of APOE gene on health and disease

Researchers are testing the effectiveness of multiple treatments to prevent COVID-19

Identifying, preventing and treating drug-induced arrhythmias

Enzyme insight could lead to new treatment approach for diabetic patients

Combining nanotechnology with immunotherapy to fight deadly metastatic breast cancer

Drug for liver cirrhosis shows potential to treat dementia and motor neuron disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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