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Glycans strengthen interaction between viral spike proteins and ACE2 receptors on host cells

A new study shows that the ACE2 and RBD of coronavirus spike fragments have different binding strengths and dissociation rates when they are glycosylated and non-glycosylated.

13 Dec 2021

Evaluating the virucidal activity of blue LED light against SARS-CoV-2 infection

A new study provides some possible explanations to the mechanisms by which antiviral activity is exerted by blue LED light and indicated that the alteration of the SARS-CoV-2 spike protein requires the presence of photosensitizers.

13 Dec 2021

Impact of tumor environments on susceptibility and course of disease in those infected with SARS-CoV-2

A review assessed the impact of "hot" vs. "cold" immune/tumor environments (and associated therapies) on susceptibility and disease course in subjects with these two types of tumors and infected with SARS-CoV-2 to decipher the mechanisms that drive these adverse outcomes in COVID-19 infected cancer patients.

13 Dec 2021

SARS-CoV-2 omicron variant may evade host immune responses

A recent study has demonstrated that the omicron variant of severe acute respiratory syndrome coronavirus 2 has a higher ability to evade antibody-mediated neutralization than other variants of concern.

13 Dec 2021

What are the implications of orangutan translocation risks in the COVID-19 era?

Can orangutan translocation pose infectious disease transmission and species conservation threats?

13 Dec 2021

Third dose of SARS-CoV-2 vaccine increases protection against omicron variant

A new study examines the variation in vaccine effectiveness against virus variants using estimated reductions in neutralizing antibody levels from published studies.

13 Dec 2021

COVID-19 in association with pre-existing mental and physical health issues

The present study attempts to identify the factors that increase the risk of COVID-19 infection or confer protection against COVID-19 in a study population above 55 years of age known to experience higher morbidity and risk of mortality from COVID-19.

13 Dec 2021

Sarcopenia and COVID-19

The present study attempts to investigate if sarcopenia, which is a condition where there is loss of skeletal muscle mass and function, may result in poor clinical outcomes in COVID-19 patients.

13 Dec 2021

Bioinformatics pipeline can be used to quickly identify SARS-CoV-2 therapeutics

In a new study, researchers developed a bioinformatics pipeline that uses RNA sequencing data to identify altered genes and signaling pathways affected by viral infection.

13 Dec 2021

Study suggests pre-existing human common cold coronavirus antibodies hinder SARS-CoV-2 immunity

In this study cohort, SARS-CoV-2 infections were confirmed via the RT-PCR test.

13 Dec 2021

Seasonal coronaviruses may help estimate SARS-CoV-2 reinfection risk

New research suggests that common human coronaviruses, such as those that cause the common cold, could also shed light on the patterns of SARS-CoV-2 reinfection.

13 Dec 2021

Researchers develop a universal SARS-CoV-2 neutralizing antibody

A new study has been published in Frontiers in Immunology, where scientists developed a universal SARS-CoV-2 neutralizing antibody, MG1141A.

13 Dec 2021

MV130 immunotherapy boosts natural and vaccine-induced SARS-CoV-2 immunity in mice

A new mouse study found that intranasal administration of MV130 protected against severe acute respiratory syndrome coronavirus 2.

13 Dec 2021

Online analysis of Long COVID narratives

In a new study published in Digital Health, scientists built a knowledge base starting with the patient. Using social media data, they aimed to understand what rehabilitation strategies could be adopted for those living with Long COVID.

13 Dec 2021

Cellular properties of SARS-CoV-2 spike protein RBD in virus-infected African green monkey kidney epithelial cells

Researchers from the Biological Defence Programme of Singapore have investigated six of these antibodies.

13 Dec 2021

SARS-CoV-2-specific T cell and antibody responses in healthcare workers that suffered from COVID-19 one year ago

Researchers have been investigating the immune response in previously infected healthcare workers after they receive these vaccines.

13 Dec 2021

A method to eliminate mutants in the furin cleavage site of SARS-CoV-2 in Calu-3 cells

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12 Dec 2021

Nasal infection drives lethal lung injury due to SARS-CoV-2 in mice

A new study demonstrates lethal infection of the olfactory epithelium in a mouse model that could help understand the mechanisms of COVID-19.

12 Dec 2021

Proactive wins over reactive responses to COVID-19

A new study looks at how the impact of non-pharmaceutical interventions can be quantified and assessed for robustness and resilience.

12 Dec 2021

An assessment of COVID-19 mortality risk using patient biomarker time series

A new study discusses the use of multiple biomarkers taken over the course of hospitalization in COVID-19 patients to determine the risk of mortality.

12 Dec 2021

Severe Acute Respiratory News and Research

Glycans strengthen interaction between viral spike proteins and ACE2 receptors on host cells

Evaluating the virucidal activity of blue LED light against SARS-CoV-2 infection

Impact of tumor environments on susceptibility and course of disease in those infected with SARS-CoV-2

SARS-CoV-2 omicron variant may evade host immune responses

What are the implications of orangutan translocation risks in the COVID-19 era?

Third dose of SARS-CoV-2 vaccine increases protection against omicron variant

COVID-19 in association with pre-existing mental and physical health issues

Sarcopenia and COVID-19

Bioinformatics pipeline can be used to quickly identify SARS-CoV-2 therapeutics

Study suggests pre-existing human common cold coronavirus antibodies hinder SARS-CoV-2 immunity

Seasonal coronaviruses may help estimate SARS-CoV-2 reinfection risk

Researchers develop a universal SARS-CoV-2 neutralizing antibody

MV130 immunotherapy boosts natural and vaccine-induced SARS-CoV-2 immunity in mice

Online analysis of Long COVID narratives

Cellular properties of SARS-CoV-2 spike protein RBD in virus-infected African green monkey kidney epithelial cells

SARS-CoV-2-specific T cell and antibody responses in healthcare workers that suffered from COVID-19 one year ago

A method to eliminate mutants in the furin cleavage site of SARS-CoV-2 in Calu-3 cells

Nasal infection drives lethal lung injury due to SARS-CoV-2 in mice

Proactive wins over reactive responses to COVID-19

An assessment of COVID-19 mortality risk using patient biomarker time series

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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