Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Cholesterol-fighting statins inhibit uterine fibroid tumors that account for 50% of hysterectomies

Researchers at the University of Texas Medical Branch at Galveston, in collaboration with The University of Texas Health Science Center at Houston (UTHealth), Baylor College of Medicine and the Georgia Regents University, report for the first time that the cholesterol-lowering drug simvastatin inhibits the growth of human uterine fibroid tumors.

16 Nov 2014

A single gene mutation can halve the risk of heart disease

Recent research has shown that inactivation of a single gene reduces the risk of heart attack by 50%.

14 Nov 2014

Exposure to tobacco smoke, roadway air pollution can contribute to obesity

New research from Keck Medicine of the University of Southern California (USC) bolsters evidence that exposure to tobacco smoke and near-roadway air pollution contributes to the development of obesity.

14 Nov 2014

Rare gene mutation linked to lower cholesterol levels, reduced risk of heart attack

Rare mutations that shut down a single gene are linked to lower cholesterol levels and a 50 percent reduction in the risk of heart attack, according to new research from Washington University School of Medicine in St. Louis, the Broad Institute at Massachusetts Institute of Technology and Harvard, and other institutions.

14 Nov 2014

Estrogen plays key role in regulating blood pressure, LDL cholesterol levels

What makes some women more susceptible to heart disease than others? To help answer that question, researchers at Western University's Robarts Research Institute have identified that an estrogen receptor, previously shown to regulate blood pressure in women, also plays an important role in regulating low-density lipoprotein (LDL) cholesterol levels.

13 Nov 2014

Metabolic syndrome screening in bipolar disorder warranted

The frequency of the metabolic syndrome in patients with bipolar disorder warrants systematic screening, say researchers, particularly among men, older patients and those receiving atypical antipsychotic treatment.

12 Nov 2014

FDA accepts Amgen's evolocumab BLA for review

Amgen today announced that the U.S. Food and Drug Administration has accepted for review Amgen's Biologics License Application (BLA) for evolocumab for the treatment of high cholesterol.

11 Nov 2014

Moderate alcohol consumption can protect against coronary heart disease, but only for some people

A new study at Sahlgrenska Academy, University of Gothenburg, confirms that moderate alcohol consumption can protect against coronary heart disease.

10 Nov 2014

Applying lessons learnt from failed Alzheimer's studies for future research

Disappointing results in clinical Alzheimer's studies discourage doctors and scientists from continuing their research into ɣ-secretases and a possible treatment against Alzheimer's disease. In the prestigious journal Cell, the Alzheimer's expert Bart De Strooper (VIB-KU Leuven) argues that these studies are not pointless, but merely indicate what the next steps should be for the Alzheimer's research.

7 Nov 2014

Obeticholic acid improves liver health in people with nonalcoholic steatohepatitis

An experimental drug aimed at treating a common liver disease showed promising results and potential problems in a multicenter clinical trial funded by the National Institutes of Health. The FLINT study found that people with nonalcoholic steatohepatitis (NASH) who took obeticholic acid (OCA) had improved liver health during that period, including decreased inflammation and fat in the liver and decreased body weight versus people receiving a placebo. OCA was also associated with increases in itching and total cholesterol.

7 Nov 2014

Only one in every two young adults with hypertension receives advice on how to lower blood pressure

Far too many "teachable moments" are lost in a doctor's office during which young adults with hypertension could have learned how to reduce their blood pressure. In fact, only one in every two hypertensive young Americans does in fact receive such advice and guidance from a healthcare provider within a year from being diagnosed, says Heather M. Johnson of the University of Wisconsin School of Medicine and Public Health in the US.

7 Nov 2014

IU School of Medicine researchers identify new protein that can control diabetes

Indiana University School of Medicine researchers have identified a small protein with a big role in lowering plasma glucose and increasing insulin sensitivity.

6 Nov 2014

Effects of unhealthy lifestyle persist even after atherosclerosis treatment

Almost everyone knows that improving your eating habits will most likely improve your health. What most people may not know, however, is that the effects of poor eating habits persist long after dietary habits are improved. In a new report appearing in the November 2014 issue of the Journal of Leukocyte Biology, scientists use mice to show that even after successful treatment of atherosclerosis (including lowering of blood cholesterol and a change in dietary habits) the effects of an unhealthy lifestyle still affect the way the immune system functions.

6 Nov 2014

New mobile wireless system for monitoring elderly people at homes

Fraunhofer FIT demonstrates a mobile wireless system that monitors the health of elderly people in their own homes, using miniature sensors. Besides non-invasive sensors this platform integrates technology to take a blood sample and to determine specific markers in the patient's blood.

5 Nov 2014

MSD announces Phase 2b results of doravirine therapy in untreated patients with HIV-1 infection

Merck Sharp & Dohme Ltd. MSD (known as Merck & Co., Inc. in the United States and Canada), today announced the presentation of results from a Phase 2b clinical trial evaluating the safety and efficacy of once daily oral doravirine, an investigational next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI), plus tenofovir/emtricitabine (TDF/FTC) compared to efavirenz plus TDF/FTC in previously untreated patients with HIV-1 infection.

4 Nov 2014

Krembil researchers potentially discover major cause of dementia

Researchers at the Krembil Neuroscience Centre have potentially discovered a major cause of dementia. In this type of dementia, there is damage to the white matter (nerve fibres) of the brain apparent on computerized tomography (CT) and magnetic resonance imaging (MRI) scans of older individuals.

31 Oct 2014

Einstein-Montefiore researchers to present latest finding on aging research at GSA 2014

Investigators at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center will present their latest aging research at the Gerontological Society of America's 67th Annual Scientific Meeting.

31 Oct 2014

Physical health management below par in schizophrenia patients

The diagnosis and treatment of physical ailments in patients with schizophrenia falls below acceptable standards, shows a national audit of patients in England and Wales.

30 Oct 2014

Oats play important role in human health

According to a new, wide-reaching collection of scientific reviews published in the October 2014 supplement issue of the British Journal of Nutrition, oats may play an important role in improving satiety, diet quality and digestive, cardiovascular and general metabolic health.

30 Oct 2014

Study: Certain prostate cancer medications linked to cardiac death risk

A new study has found that certain prostate cancer medications are linked with an increased risk of dying from heart-related causes in men with congestive heart failure or prior heart attacks. Published in BJU International, the findings will help doctors and patients weigh the benefits and risks of the drugs.

30 Oct 2014

Cholesterol News and Research

Further Reading

Cholesterol-fighting statins inhibit uterine fibroid tumors that account for 50% of hysterectomies

A single gene mutation can halve the risk of heart disease

Exposure to tobacco smoke, roadway air pollution can contribute to obesity

Rare gene mutation linked to lower cholesterol levels, reduced risk of heart attack

Estrogen plays key role in regulating blood pressure, LDL cholesterol levels

Metabolic syndrome screening in bipolar disorder warranted

FDA accepts Amgen's evolocumab BLA for review

Moderate alcohol consumption can protect against coronary heart disease, but only for some people

Applying lessons learnt from failed Alzheimer's studies for future research

Obeticholic acid improves liver health in people with nonalcoholic steatohepatitis

Only one in every two young adults with hypertension receives advice on how to lower blood pressure

IU School of Medicine researchers identify new protein that can control diabetes

Effects of unhealthy lifestyle persist even after atherosclerosis treatment

New mobile wireless system for monitoring elderly people at homes

MSD announces Phase 2b results of doravirine therapy in untreated patients with HIV-1 infection

Krembil researchers potentially discover major cause of dementia

Einstein-Montefiore researchers to present latest finding on aging research at GSA 2014

Physical health management below par in schizophrenia patients

Oats play important role in human health

Study: Certain prostate cancer medications linked to cardiac death risk

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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