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New protein shows potential for treating systolic heart failure

The heart is a muscle like no other, beating 60 to 100 times per minute on average, around the clock. But when it grows weak, it can lead to serious problems: from debilitating shortness of breath and swelling in the legs and feet, to fluid in the lungs and even death.

16 Oct 2024

FDA-approved breast cancer drug shows promise for appendix cancer

Researchers at University of California San Diego School of Medicine found an FDA-approved drug used to treat breast cancer has the potential to be an effective therapeutic for a specific type of appendix cancer.

16 Oct 2024

Innovative nanoparticle therapy offers hope in fighting prostate cancer

Prostate cancer is the second leading cause of cancer death among American men.

16 Oct 2024

Immunotherapy sets new standard for Hodgkin lymphoma care

A treatment that rallies the immune system to destroy cancer raised the survival rate for advanced Hodgkin lymphoma patients to a remarkable 92 percent, suggesting a new standard therapy for the disease.

16 Oct 2024

Adenine base editors show potential to correct X-CGD-causing mutations

A collaborative effort between investigators at the National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID) and Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system, demonstrates the potential of precise genome editing technologies, called adenine base editors, to correct disease-causing mutations in stem cells from patients with X-linked chronic granulomatous disease (X-CGD), a rare genetic disorder characterized by high susceptibility to infections.

16 Oct 2024

Groundbreaking discovery offers hope for patients suffering from toxic epidermal necrolysis

A global team of researchers at the Max Planck Institute of Biochemistry has made a groundbreaking discovery that saves the lives of patients suffering from toxic epidermal necrolysis.

16 Oct 2024

Bacteriophages unveil auxiliary genes critical for infection

Viruses that infect bacteria—known as bacteriophages - could be used in a targeted manner to combat bacterial diseases.

16 Oct 2024

Cellular Origins, Fresenius Kabi sign development agreement for scalable automation of cell and gene therapy manufacturing

Cellular Origins and Fresenius Kabi, an operating company of Fresenius, announce today they have signed a development agreement that leverages each company’s expertise in cell and gene therapies (CGTs).

16 Oct 2024

Young people with ADHD benefit from tactile massage

Tactile massage can relieve hyperactivity, impulsivity and attention deficit in ADHD. This is the result of a small-scale study conducted at the University of Gothenburg.

16 Oct 2024

AI models boost detection of cognitive decline in medical records, study finds

This study assesses large language models for early detection of cognitive decline, highlighting their strengths and limitations compared to conventional AI.

16 Oct 2024

NYU Langone researchers address the challenges of heart failure in cancer patients

A new scientific statement issued today by the Heart Failure Society of America highlights a critical connection between heart failure (HF) and cancer, with shared mechanisms contributing to the incidence and progression of both diseases.

16 Oct 2024

Harnessing the power of miRNA for cancer diagnosis and treatment

This study is led by Dr. Shiwei Duan (Department of Clinical Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang, China). His team analyzed literature on miRNA, summarizing the close relationship between these small molecules and cancer. miRNA is a type of non-coding RNA that does not encode proteins, but can target more than 60% of human protein-coding genes.

15 Oct 2024

Short course chemotherapy boosts survival rates in cervical cancer patients

Cervical cancer patients were significantly more likely to be alive and cancer-free after five years when given a short course of chemotherapy prior to chemoradiation, finds a clinical trial led by researchers from UCL and UCLH.

15 Oct 2024

Distinct immune profiles linked to adverse reactions from immunotherapy

Distinct immune "signatures" in patients who develop adverse events while taking immunotherapy for cancer may help oncologists identify patients at risk and treat them early to prevent serious side effects, suggests a study by researchers from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

15 Oct 2024

Genetic insights transform treatment for children with developmental disorders

Thousands of children with severe developmental disorders have benefited from more targeted treatments and support with genetic insights from the large-scale Deciphering Developmental Disorders (DDD) study, finds a new study.

15 Oct 2024

Study: Fear of cancer recurrence is common among adult survivors of childhood cancer

A new study by Concordia researchers suggests that one-third of adult survivors of childhood cancer experience a fear of cancer recurrence so severe that it can seriously impact their daily lives.

15 Oct 2024

SU2C announces grants to support cutting-edge research in a variety of cancers

Stand Up To Cancer (SU2C) today announced grants to several teams of leading cancer investigators in support of cutting-edge research in a variety of cancers including head and neck, pediatric, pancreatic, breast, rectal and gastro-esophageal cancers, as well as research focused on how the microbiome communicates with the immune system.

15 Oct 2024