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Malaria parasite protein essential for parasite invasion into red blood cells

A new study led by researchers at Harvard T.H. Chan School of Public Health finds that a malaria parasite protein called calcineurin is essential for parasite invasion into red blood cells. Human calcineurin is already a proven target for drugs treating other illnesses including adult rheumatoid arthritis and lupus, and the new findings suggest that parasite calcineurin should be a focus for the development of new antimalarial drugs.

26 Jun 2015

New study reveals key part of Ebola virus life cycle at higher resolution than ever before

A new study led by scientists at The Scripps Research Institute (TSRI) reveals a key part of the Ebola virus life cycle at a higher resolution than ever before. The research sheds light on how Ebola virus assembles—and how researchers might stop the often-fatal infection.

26 Jun 2015

Alabama scientists show how phytochemical in magnolia works against head and neck cancers

Magnolias are prized for their large, colorful, fragrant flowers. Does the attractive, showy tree also harbor a potent cancer fighter?

26 Jun 2015

Gene-encoded protein may be effective in early detection of pancreatic cancer

A protein encoded by the gene glypican-1 (GPC1) present on cancer exosomes may be used as part of a potential non-invasive diagnostic and screening tool to detect early pancreatic cancer, potentially at a stage amenable to surgical treatment, according to a study at The University of Texas MD Anderson Cancer Center.

24 Jun 2015

Novogen’s chemotherapy drug Anisina proves as effective anti-cancer agent in animals

US-Australian drug discovery company, Novogen Limited announced today that its candidate cytotoxic chemotherapy drug, Anisina, has proved an effective anti-cancer agent in animals, the result of which it now has been fast-tracked by the Company to come into the clinic.

24 Jun 2015

Researchers develop new implantable drug-delivery system using nanowire

A team of researchers has created a new implantable drug-delivery system using nanowires that can be wirelessly controlled.

24 Jun 2015

Groundbreaking UVA research may lead to creation of male contraceptive

Groundbreaking new reproductive research from the School of Medicine has identified key molecular events that could be playing a critical role as sperm and egg fuse to create new life. The findings might one day lead to the creation of a male contraceptive.

24 Jun 2015

Discovery may accelerate development of new drugs to treat Huntington's disease

By identifying in spinal fluid how the characteristic mutant proteins of Huntington's disease spread from cell to cell, UC Irvine scientists and colleagues have created a new method to quickly and accurately track the presence and proliferation of these neuron-damaging compounds -- a discovery that may accelerate the development of new drugs to treat this incurable disease.

24 Jun 2015

PolyU develops novel big data analysis platform for analyzing interactions among cancer genes

The Hong Kong Polytechnic University has achieved a breakthrough in the cancer genomics by developing a novel big data analysis platform for analyzing the interactions among genes. The analysis platform unveils the unregulated patterns of gene network in cancer and discovers potential diagnostic and therapeutic target genes, Nucleophosmin (NPM1) and its associated genes, in Chronic Myelogenous Leukemia (CML).

24 Jun 2015

Discovery provides basis for new pertussis treatments

The worldwide spreading of the whooping cough, also known as pertussis, has substantially increased since 2010. Researchers from the Biozentrum, University of Basel, have investigated structure and function of an important membrane protein of the bacterium causing pertussis. They discovered that the protein structure differs from a previously postulated model.

24 Jun 2015

UMass Amherst reports how two molecular pathways get together to ensure normal bacterial growth

As part of their long-term investigation of regulatory factors in the bacterial cell cycle, molecular biologists at the University of Massachusetts Amherst now report finding a surprising new role for one factor, CpdR, an adaptor that helps to regulate selective protein destruction, the main control mechanism of cell cycle progression in bacteria, at specific times.

23 Jun 2015

Statins benefit patients undergoing major lung resection, lower major complications

Statins have been shown to reduce complications from cardiovascular surgery. To determine whether statins might also help those undergoing major lung surgeries, a team at Memorial Sloan Kettering Cancer Center conducted a well-designed study that randomized patients to receive either a statin or placebo before and after surgery.

23 Jun 2015

Israeli researchers establish novel optogenetic method for cardiac pacing and resynchronization

Israeli researchers have successfully established a new approach for pacing the heart and synchronizing its mechanical activity without the use of a conventional electrical pacemaker. This novel biologic strategy employs light-sensitive genes that can be injected into the heart and then activated by flashes of blue light.

23 Jun 2015

UT Southwestern researchers identify two proteins within fetal lungs that initiate labor process

Researchers at UT Southwestern Medical Center have identified two proteins in a fetus' lungs responsible for initiating the labor process, providing potential new targets for preventing preterm birth.

23 Jun 2015

UT Southwestern scientists devise new technique to identify cell that replenishes adult heart muscle

Regenerative medicine researchers at UT Southwestern Medical Center have identified a cell that replenishes adult heart muscle by using a new cell lineage-tracing technique they devised.

23 Jun 2015

Purdue University-led study could lead to better treatments for people infected with MERS virus

A Purdue University-led team of researchers studying the Middle East Respiratory Syndrome, or MERS, have found molecules that shut down the activity of an essential enzyme in the virus and could lead the way to better treatments for those infected.

23 Jun 2015

PSMA can be an ideal target for diagnosis and treatment of prostate cancer

Prostate-specific membrane antigen (PSMA) is a surface protein that is normally present on healthy prostate cells, but is found at much higher levels on prostate cancer cells. It is barely found in the rest of the body. "Therefore, PSMA is an ideal target for diagnostic purposes as well as targeted therapies against prostate cancer," says biotechnologist Dr. Matthias Eder of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ).

23 Jun 2015

Experimental vaccine candidate can stimulate immune system activity to prevent HIV infection

New research led by scientists at The Scripps Research Institute (TSRI), International AIDS Vaccine Initiative (IAVI) and The Rockefeller University shows in mice that an experimental vaccine candidate designed at TSRI can stimulate the immune system activity necessary to stop HIV infection. The findings could provide key information for the development of an effective AIDS vaccine.

22 Jun 2015

New research sheds light on molecular architecture of receptors linked to many brain diseases

Scientists at The Scripps Research Institute have teamed up with several other institutions and pharmaceutical companies, including the University of Southern California (USC), San Diego's Receptos Inc. and Japanese company Ono Pharmaceutical Co., Ltd., to publish the first 3D structures of a receptor implicated in many diseases of the brain and in normal physiology throughout the body.

22 Jun 2015

TSRI scientists devise powerful set of chemical methods to explore protein biology

Scientists at The Scripps Research Institute (TSRI) have devised a powerful set of chemical methods for exploring the biology of proteins.

22 Jun 2015

G Protein News and Research

Malaria parasite protein essential for parasite invasion into red blood cells

New study reveals key part of Ebola virus life cycle at higher resolution than ever before

Alabama scientists show how phytochemical in magnolia works against head and neck cancers

Gene-encoded protein may be effective in early detection of pancreatic cancer

Novogen’s chemotherapy drug Anisina proves as effective anti-cancer agent in animals

Researchers develop new implantable drug-delivery system using nanowire

Groundbreaking UVA research may lead to creation of male contraceptive

Discovery may accelerate development of new drugs to treat Huntington's disease

PolyU develops novel big data analysis platform for analyzing interactions among cancer genes

Discovery provides basis for new pertussis treatments

UMass Amherst reports how two molecular pathways get together to ensure normal bacterial growth

Statins benefit patients undergoing major lung resection, lower major complications

Israeli researchers establish novel optogenetic method for cardiac pacing and resynchronization

UT Southwestern researchers identify two proteins within fetal lungs that initiate labor process

UT Southwestern scientists devise new technique to identify cell that replenishes adult heart muscle

Purdue University-led study could lead to better treatments for people infected with MERS virus

PSMA can be an ideal target for diagnosis and treatment of prostate cancer

Experimental vaccine candidate can stimulate immune system activity to prevent HIV infection

New research sheds light on molecular architecture of receptors linked to many brain diseases

TSRI scientists devise powerful set of chemical methods to explore protein biology

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How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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