Transplant News and Research

RSS

Study examines link between SES and access to lung transplantation in adult CF patients

Adult cystic fibrosis (CF) patients of low socioeconomic status (SES) have a greater chance of not being accepted for lung transplant after undergoing initial evaluation, according to a new study.

14 Sep 2012

Smoking history 'no bar to successful lung donation'

Although lung transplantation from donors with a positive smoking history is associated with worse outcomes than with lungs from non-smoking donors, survival is still better than remaining on the waiting list, say UK researchers.

13 Sep 2012

University of Maryland study findings advance navel nephrectomy as standard of care

In the largest study of its kind, living donors who had a kidney removed through a single port in the navel report higher satisfaction in several key categories, compared to donors who underwent traditional multiple-port laparoscopic removal.

13 Sep 2012

Ethnicity, race affect likelihood of finding suitable unrelated stem cell donors for cancer patients

Researchers at Moffitt Cancer Center and colleagues have published a study describing the greater difficulty in finding matched, unrelated donors for non-Caucasian patients who are candidates for hematopoietic cell transplantation (HCT).

12 Sep 2012

New model reveals how immune system functions under conditions of neutropenia

Cancer chemotherapy can be a life-saver, but it is fraught with severe side effects, among them an increased risk of infection. Until now, the major criterion for assessing this risk has been the blood cell count: if the number of white blood cells falls below a critical threshold, the risk of infection is thought to be high.

12 Sep 2012

Scripps scientists discover new antibody-discovery technique

Scientists at The Scripps Research Institute have found a new technique that should greatly speed the discovery of medically and scientifically useful antibodies, immune system proteins that detect and destroy invaders such as bacteria and viruses. New methods to discover antibodies are important because antibodies make up the fastest growing sector of human therapeutics; it is estimated that by 2014 the top-three selling drugs worldwide will be antibodies.

12 Sep 2012

Two National University of Singapore scientists win Lasker Awards for medical research

Two scientists from the National University of Singapore (NUS) - Professor Michael Sheetz, Director of the Mechanobiology Institute of Singapore; and Professor Roy Calne, Visiting Professor with the NUS Yong Loo Lin School of Medicine's Department of Surgery - have been conferred the prestigious Lasker Awards for making great advances in medical research.

11 Sep 2012

DATATRAK announces technology and services agreement with Bellicum

DATATRAK International, Inc., a technology and services company focused on global eClinical solutions for the clinical trials industry, today announced the award of a multi-million dollar, five-year technology and services agreement with Bellicum Pharmaceuticals.

11 Sep 2012

Blood flow simulation tools can test and optimize Berlin Heart design

Structural and mechanical engineers at the University of California, San Diego, are working together to create blood flow simulations that could lead to improvements in the design of a cardiac pump for children born with heart defects. They hope that the design changes will improve young patients' outcomes.

11 Sep 2012

Cardiac stem cells from newborns show stronger regenerative ability

Researchers at the University of Maryland School of Medicine, who are exploring novel ways to treat serious heart problems in children, have conducted the first direct comparison of the regenerative abilities of neonatal and adult-derived human cardiac stem cells.

11 Sep 2012

Cell Therapeutics launches Pixuvri in the European Union

Cell Therapeutics, Inc., a company focused on translating science into novel cancer therapies, today announced the initiation of the commercial launch of Pixuvri in the European Union with entry into Sweden, Denmark and Finland in September, to be followed by Austria and Norway in early October 2012 and Germany, United Kingdom and the Netherlands in November 2012.

11 Sep 2012

Warning over sirolimus in HCV-positive liver transplantation

Sirolimus, whether given at the time of liver transplantation or after, is associated with poorer outcomes in patients with hepatitis C virus infection compared with those who do not take the immunosuppressant, shows a US study.

10 Sep 2012

Researchers identify three genetic regions associated with primary biliary cirrhosis

Researchers have newly identified three genetic regions associated with primary biliary cirrhosis (PBC), the most common autoimmune liver disease, increasing the number of known regions associated with the disorder to 25.

10 Sep 2012

People with kidney stones more likely to need dialysis or transplant later in life

People who have had kidney stones are twice as likely to need dialysis or a kidney transplant later in life, demonstrates recently published findings by medical researchers at the University of Alberta. Their article was recently published in the British Medical Journal.

7 Sep 2012

Study finds excellent outcomes for patients with acute liver failure after LDLT

Patients in Japan who underwent living donor liver transplantation (LDLT) for acute liver failure (ALF) were classified as having excellent outcomes, with ten-year survival at 73%.

7 Sep 2012

Longer looks: Insurers balk at price of new asthma relief; Despite health law, costs still overwhelming for some patients

For two decades, Patricia DiGiusto struggled with severe asthma. Powerful medications and frequent use of her inhaler could not prevent repeated trips to the emergency room. ... Two years ago, Ms. DiGiusto's doctor told her about a new procedure called bronchial thermoplasty, the first non-drug therapy approved by the Food and Drug Administration for patients with severe asthma.

7 Sep 2012

Study sheds new light on why most bone marrow transplant patients suffer acute GVHD

A team of scientists led by a bone marrow transplant researcher at Fred Hutchinson Cancer Research Center has shed new light on why most bone marrow transplant patients who receive tissue-matched cells from unrelated donors still suffer acute graft-versus-host disease (GVHD).

6 Sep 2012

Alnylam announces complete results from ALN-RSV01 Phase IIb trial on RSV infection

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today complete results from its Phase IIb trial with ALN-RSV01 for the treatment of respiratory syncytial virus (RSV) infection in lung transplant patients.

6 Sep 2012

Rigel commences R343 and R333 Phase 2 studies in allergic asthma, discoid lupus erythematosus

Rigel Pharmaceuticals, Inc. today announced that it has commenced Phase 2 clinical studies with two of the company's most advanced proprietary therapeutic product candidates. R343 is an inhaled SYK inhibitor that is being evaluated as a potential treatment for allergic asthma.

6 Sep 2012

NCI awards Soligenix $300,000 SBIR grant for orBec Phase 2 chronic GI GVHD trial

Soligenix, Inc., a development stage biopharmaceutical company, announced today that the National Cancer Institute has awarded Soligenix a Small Business Innovation Research grant to support the conduct of a Phase 2 clinical trial designed to evaluate orBec (oral beclomethasone 17,21-dipropionate or BDP) as a treatment for the gastrointestinal manifestation of chronic Graft-versus-Host disease.

5 Sep 2012

Transplant News and Research

Study examines link between SES and access to lung transplantation in adult CF patients

Smoking history 'no bar to successful lung donation'

University of Maryland study findings advance navel nephrectomy as standard of care

Ethnicity, race affect likelihood of finding suitable unrelated stem cell donors for cancer patients

New model reveals how immune system functions under conditions of neutropenia

Scripps scientists discover new antibody-discovery technique

Two National University of Singapore scientists win Lasker Awards for medical research

DATATRAK announces technology and services agreement with Bellicum

Blood flow simulation tools can test and optimize Berlin Heart design

Cardiac stem cells from newborns show stronger regenerative ability

Cell Therapeutics launches Pixuvri in the European Union

Warning over sirolimus in HCV-positive liver transplantation

Researchers identify three genetic regions associated with primary biliary cirrhosis

People with kidney stones more likely to need dialysis or transplant later in life

Study finds excellent outcomes for patients with acute liver failure after LDLT

Longer looks: Insurers balk at price of new asthma relief; Despite health law, costs still overwhelming for some patients

Study sheds new light on why most bone marrow transplant patients suffer acute GVHD

Alnylam announces complete results from ALN-RSV01 Phase IIb trial on RSV infection

Rigel commences R343 and R333 Phase 2 studies in allergic asthma, discoid lupus erythematosus

NCI awards Soligenix $300,000 SBIR grant for orBec Phase 2 chronic GI GVHD trial

Industry Focus eBook - Cell biology (5th edition) eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

Latest News