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First genome-scale model of microbe that causes tuberculosis

Tuberculosis remains one of the biggest killers in the world today being responsible for nearly ten million cases and one and a half million deaths each year.

23 Jun 2007

Entecavir can compromise HIV treatment

Treating hepatitis B patients with the drug entecavir can cause those who are also infected with HIV to become resistant to two of the most important drugs in the anti-HIV arsenal, according to a new report in the New England Journal of Medicine.

23 Jun 2007

Genzyme files for FDA approval of single-treatment Synvisc-One

Genzyme Corp. has announced that it has filed with the U.S. Food and Drug Administration (FDA) for approval of Synvisc-One, the single treatment of Synvisc (hylan G-F 20) that provides up to six months of pain relief from osteoarthritis (OA) of the knee.

23 Jun 2007

Drug warning prompts treatment changes for those infected with hepatitis B and HIV

Cross-resistance alarms raised earlier this year by Johns Hopkins researchers about a widely used antiviral therapy for hepatitis B liver infections have prompted swift treatment revisions by the drug's maker and governmental agencies.

23 Jun 2007

Sea-squirt derived drug trabectedin shows promise as cancer treatment

The sea-squirt derived drug trabectedin (ecteinascidinin-743) shows anti-tumour activity in more than half of patients with a specific type of cancer, conclude authors of an article published early Online and in the July edition of The Lancet Oncology.

22 Jun 2007

New trade agreement language to allow developing countries more flexibility in circumventing drug patents, other restrictions

Democratic lawmakers and U.S. trade officials are in the final stages of negotiation over language to be added to international free trade agreements that would allow developing countries more flexibility in circumventing drug patents and other restrictions on pharmaceuticals, sources said recently, CongressDaily reports.

22 Jun 2007

Report examines programs that would give HIV-positive people access to new drugs before final federal approval

"Rethinking the Approach to Expanded Access Programs," Forum for Collaborative HIV Research: The report says that reform of expanded access programs that allow HIV-positive people to take new drugs before final federal approval is needed.

22 Jun 2007

Texas sues three drug makers alleging Medicaid fraud

Texas on Wednesday filed lawsuits against Mylan Laboratories, Sandoz, Teva Pharmaceuticals and subsidiaries of those companies alleging that the state Medicaid program overpaid retailers by at least tens of millions of dollars for medications because the companies did not disclose discounts they were providing to retailers, the Houston Chronicle reports.

22 Jun 2007

House Committee passes prescription drug user fee act reauthorization legislation

The House Energy and Commerce Committee on Thursday voted 39-0 to approve nine bills that would expand FDA's authority to regulate prescription drug safety and increase user fees paid by drug and medical device companies, Dow Jones reports.

22 Jun 2007

FDA makes final ruling on dietary supplements

The U.S. Food and Drug Administration today announced a final rule establishing regulations to require current good manufacturing practices (cGMP) for dietary supplements.

22 Jun 2007

Whitehead scientist to study key mechanism in cell division

"Cell division is one of the most fundamental aspects of biology, the process that makes life," says Iain Cheeseman, PhD. "And it has an intrinsic beauty."

22 Jun 2007

WHO-based tropical disease research programme to focus on emerging diseases

The World Health Organization (WHO) based Special Programme for Research and Training in Tropical Diseases (TDR) has adopted a new strategy for strengthening and expanding research to prevent and control 'infectious diseases of poverty.'

22 Jun 2007

New plan to contain extensively drug-resistant TB (XDR-TB)

Hundreds of thousands of cases of drug-resistant tuberculosis (TB) can be prevented and as many as 134 000 lives saved through the implementation of a two-year response plan, published/launched today by the World Health Organization (WHO) and the Stop TB Partnership.

22 Jun 2007

Multifunctional nanoparticle platforms for targeting and imaging cancer cells

There has been much recent interest in how nanotechnology will impact the field of medicine. Unfortunately, a number of promising nanostructured systems have turned out to be extremely toxic to humans, thus precluding their use in clinical applications and dashing hopes of an early success for the interdisciplinary field of nanobiotechnology.

21 Jun 2007

Men bitten more often than women and alcohol is the culprit

A new study by doctors in Ireland has found that men are 12 times more likely than women to be bitten by another person and need surgery.

21 Jun 2007

Children as young as 11 use drugs to win at sport

According to French researchers athletes as young as eleven admit to using drugs to enhance their sporting performance.

21 Jun 2007

New treatments for migraines and chronic headaches

Twelve percent of the population, three quarters of them women, suffer at least occasionally from migraines and about 5 percent from chronic headaches.

20 Jun 2007

Men are 12 times more likely than women to sustain severe human bite injuries

The researchers reviewed the 92 patients requiring assessment for human bite wounds by the plastic surgery service at St James Hospital Dublin, Ireland, between January 2003 and December 2005. Eight five of them (92%) were men and the 92 patients had a total of 96 bites.

20 Jun 2007

Scientists develop unique “switch” that can control the activity of any protein

Our bodies could not maintain their existence without thousands of proteins performing myriad vital tasks within cells. Since malfunctioning proteins can cause disease, the study of protein structure and function can lead to the development of drugs and treatments for numerous disorders.

20 Jun 2007

Many kids using performance enhancing drugs in sport

More than one per cent of eleven year olds admit using performance enhancing drugs to do better in sports reports a study published online ahead of print in the British Journal of Sports Medicine.

20 Jun 2007