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Canada-US-Italian research team develops nature-inspired cocaine biosensor

Since the beginning of time, living organisms have developed ingenious mechanisms to monitor their environment. As part of an international study, a team of researchers has adapted some of these natural mechanisms to detect specific molecules such as cocaine more accurately and quickly. Their work may greatly facilitate the rapid screening-less than five minutes-of many drugs, infectious diseases, and cancers.

14 Feb 2013

Study shows importance of lncRNAs for regulation of adipogeneis

Whitehead Institute researchers have identified a previously unrecognized layer of genetic regulation that is necessary for the generation of undesirable white fat cells. When this regulation is disrupted, white fat cells are unable to accumulate lipid droplets or mature from their precursors.

14 Feb 2013

IAP antagonists may actually increase risk of bone tumors

Cancer drugs should kill tumors, not encourage their spread. But new evidence suggests that an otherwise promising class of drugs may actually increase the risk of tumors spreading to bone, according to researchers at Washington University School of Medicine in St. Louis.

14 Feb 2013

Study: No link between hospital readmissions and saving patient lives

A Journal of the American Medical Association study released Tuesday has found that higher hospital readmissions don't lead to fewer patient deaths.

14 Feb 2013

Theradiag’s new biotherapy monitoring kits receive CE mark approval

Theradiag, a company specializing in theranostic and in vitro diagnostics, today announced it has obtained a CE mark for two new biotherapy monitoring kits; Tocilizumab (anti-IL6R) and Rituximab (anti-CD20) that further expand the Lisa Tracker range.

14 Feb 2013

Novel approach uses adult stem cells to save sight of diabetes sufferers

Scientists at Queen's University Belfast are hoping to develop a novel approach that could save the sight of millions of diabetes sufferers using adult stem cells.

14 Feb 2013

CELF6 genetic mutation may underlie common behaviors seen in people with autism

Scientists at Washington University School of Medicine in St. Louis have identified a genetic mutation that may underlie common behaviors seen in some people with autism, such as difficulty communicating and resistance to change.

14 Feb 2013

FDA grants orphan drug status to Lentigen’s LG631-CD34 for treatment of glioblastoma multiforme

Lentigen Corporation, a biotechnology company specializing in the development and manufacture of lentiviral gene delivery products, announced today that that the U.S. Food and Drug Administration (FDA) has granted orphan drug status to P140K methylguanine methyltransferase (MGMT) transduced human CD34 cells for bone marrow protection in the treatment of glioblastoma multiforme.

14 Feb 2013

New paper advances scientific understanding of glycoproteins’ structure and function

A Simon Fraser University chemist is the lead author on a new paper that advances scientific understanding of the structure and function of glycoproteins, in particular the number and positioning of sugars on them.

14 Feb 2013

Tousled-like kinases play a key role in suppression and activation of herpesviruses

Kaposi's sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) hide within the worldwide human population. While dormant in the vast majority of those infected, these active herpesviruses can develop into several forms of cancer.

14 Feb 2013

Blood’s tendency to clot may contribute to white matter hyperintensities in post-menopausal women

New Mayo Clinic research suggests that blood may hold clues to whether post-menopausal women may be at an increased risk for areas of brain damage that can lead to memory problems and possibly increased risk of stroke. The study shows that blood's tendency to clot may contribute to areas of brain damage called white matter hyperintensities.

14 Feb 2013

Violence against pregnant women in India contributes to high maternal mortality, the Atlantic reports

The Atlantic examines the issue of violence against pregnant women in India. "In the aftermath of the high-profile gang rape of a 23-year-old medical student, discussions have raged in India about the regularity of violence against women," the magazine writes, adding, "As has been widely noted, the causes of the violence run deep. But they also are broad."

14 Feb 2013

CATT study clarifies value of genetic testing for age-related macular degeneration

New findings from a landmark clinical trial show that although certain gene variants may predict whether a person is likely to develop age-related macular degeneration (AMD), a potentially blinding eye disease that afflicts more than nine million Americans, these genes do not predict how patients will respond to Lucentis- and Avastin-, the two medications most widely used to treat the "wet" form of AMD.

13 Feb 2013

State roundup: Ga. officials end Medicaid electronic eligibility system talks

A federal judge has overturned an Arizona law that sought to block funding through the state for Planned Parenthood's health care clinics because the group also performs abortions.

13 Feb 2013

Platelet-rich plasma holds great promise in treating knee OA

A study by researchers from Hospital for Special Surgery has shown that platelet-rich plasma (PRP) holds great promise for treating patients with knee osteoarthritis.

13 Feb 2013

Bedside baths and bloodstream infections in children: an interview with Aaron Milstone

Bedside baths in the hospital are nothing new. They are typically done for patient comfort and to maintain basic personal hygiene.

13 Feb 2013

New drug delivery system can reduce size of ovarian tumors by as much as 83%

By loading fragile RNA into silicon nanoparticles, researchers from The Methodist Hospital and two other institutions found a new drug delivery system can reduce the size of ovarian tumors by as much as 83 percent -- and stop tumor growth in chemotherapy-resistant ovarian cancer tissue.

13 Feb 2013

High anti-M-llerian hormone levels signal increased likelihood of pregnancy, birth

Women with a high concentration of anti-M-llerian hormone stand a better chance of giving birth after in vitro fertilization, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

13 Feb 2013

Exposure to harmful quantities of lead may lead to juvenile delinquency

Lead is a common element but is found in old paints (including those once used on children's toys), soil, old piping, water, and the atmosphere from lead-containing vehicular fuels, even drinking vessels. At high dose it is lethal but also causes seemingly trivial symptoms such as headaches. However, in children lead can also lead to irreversible damage to the organs, the kidneys in particular, and the nervous system including the brain.

13 Feb 2013

University of Utah geneticists engineer mice that develop clear cell sarcoma

Geneticists led by University of Utah Nobel Prize Laureate Mario R. Capecchi, Ph.D., have engineered mice that develop clear cell sarcoma (CCS), a significant step in better understanding how this rare and deadly soft tissue cancer arises. The mouse model also can potentially speed the development of drugs to target genes that must be activated for the cancer to form.

13 Feb 2013

Blood News and Research

Canada-US-Italian research team develops nature-inspired cocaine biosensor

Study shows importance of lncRNAs for regulation of adipogeneis

IAP antagonists may actually increase risk of bone tumors

Study: No link between hospital readmissions and saving patient lives

Theradiag’s new biotherapy monitoring kits receive CE mark approval

Novel approach uses adult stem cells to save sight of diabetes sufferers

CELF6 genetic mutation may underlie common behaviors seen in people with autism

FDA grants orphan drug status to Lentigen’s LG631-CD34 for treatment of glioblastoma multiforme

New paper advances scientific understanding of glycoproteins’ structure and function

Tousled-like kinases play a key role in suppression and activation of herpesviruses

Blood’s tendency to clot may contribute to white matter hyperintensities in post-menopausal women

Violence against pregnant women in India contributes to high maternal mortality, the Atlantic reports

CATT study clarifies value of genetic testing for age-related macular degeneration

State roundup: Ga. officials end Medicaid electronic eligibility system talks

Platelet-rich plasma holds great promise in treating knee OA

Bedside baths and bloodstream infections in children: an interview with Aaron Milstone

New drug delivery system can reduce size of ovarian tumors by as much as 83%

High anti-M-llerian hormone levels signal increased likelihood of pregnancy, birth

Exposure to harmful quantities of lead may lead to juvenile delinquency

University of Utah geneticists engineer mice that develop clear cell sarcoma

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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