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Scientists discover how insulin-producing cells show differences in age

Diabetes researchers have puzzled for decades about why insulin-producing beta cells in one pancreatic islet often look and behave quite differently than their counterparts in the same islet or in nearby islets.

12 Apr 2017

Study may provide insight into how R-LA promotes death of hepatoma cells

A new study that measured metabolite levels over time in starved rat liver cancer cells showed that treatment with a form of alpha-lipoic acid (LA) inhibited glucose uptake and glycolysis, and led to decreased cellular glucose production from non-carbohydrate sources, which may help explain how the naturally occurring R enantiomeric form of LA (R-LA) promotes the death of hepatoma cells.

12 Apr 2017

Metabolite produced by intestinal bacteria protects against type 2 diabetes, study shows

A high concentration of indolepropionic acid in the serum protects against type 2 diabetes, shows a new study from the University of Eastern Finland. Indolepropionic acid is a metabolite produced by intestinal bacteria, and its production is boosted by a fibre-rich diet.

11 Apr 2017

Researchers map gene activity to reveal how the liver performs different functions

If you get up in the morning feeling energetic and clearheaded, you can thank your liver for manufacturing glucose before breakfast time. Among a host of other vital functions, it also clears our body of toxins and produces most of the carrier proteins in our blood.

11 Apr 2017

Overweight, obese workers more likely to take sick leave, study shows

Obese Spanish workers take more sick leave than their healthy weight colleagues, according to research in more than 174 000 employees presented today at EuroPrevent 2017.

8 Apr 2017

Study compares insulin pump therapy and injections in type 1 diabetes patients during Ramadan fasting

A new study examining the risk of fasting during Ramadan for people with type 1 diabetes compared blood glucose control and the rates of hypoglycemia and hyperglycemia between users of insulin pump therapy versus multiple daily insulin injections.

7 Apr 2017

FDA authorizes marketing of first direct-to-consumer GHR tests for certain diseases

The U.S. Food and Drug Administration today allowed marketing of 23andMe Personal Genome Service Genetic Health Risk (GHR) tests for 10 diseases or conditions.

6 Apr 2017

HIIT increases glucose metabolism and insulin sensitivity in diabetics, research reveals

New research reveals that high-intensity interval training (HIIT) increases glucose metabolism in muscles as well as insulin sensitivity in type 2 diabetes. Already after a two-week training period, the glucose uptake in thigh muscles returned to a normal level.

6 Apr 2017

Are we sleeping less than we used to?

There's no solid evidence that we sleep fewer hours today than we ever did, this is something I have gone into large amounts of detail in my book, in my published papers and at a recent meeting at the Royal Society of Medicine.

6 Apr 2017

Cellular markers of aging could reveal how insulin-producing cells begin to fail in type 2 diabetes

5 Apr 2017

Tumor microenvironment poses unique challenges for effective ovarian cancer T-cell therapy

Fred Hutchinson Cancer Research Center immunotherapy researchers Drs. Kristin Anderson and Philip Greenberg and their colleagues are working on ways to tweak their team's early successes with T-cell therapy for leukemia to apply to solid tumors.

5 Apr 2017

Low normalized grip strength linked to cardiometabolic diseases and disabilities in adults

A simple test to determine a person's grip strength may be a predictor of developing metabolic disorders in middle or older age, a new cross-continental study has found.

5 Apr 2017

Liver shows positive response to leptin therapy in patients with partial lipodystrophy, study finds

Researchers at Michigan Medicine have found the livers of patients with a rare disease that affects metabolism have responded positively to leptin therapy.

5 Apr 2017

Study finds cardio-metabolic risk factors even in individuals with normal BMI

A new research study has found that approximately one-third of all individuals with a normal body mass index (BMI) had cardio-metabolic risk factors for heart disease, especially those of South Asian and Hispanic descent.

5 Apr 2017

Research suggests using combined OGTT and HbA1C tests to screen children at high risk of diabetes

Doctors should add an oral glucose tolerance test (OGTT) to their hemoglobin A1C (HbA1C) when they screen high-risk children for prediabetes and diabetes, new research from South Korea suggests.

4 Apr 2017

Short-term fasting during chemotherapy may counteract side effects of common cancer drugs

A short-term fast appears to counteract increases in blood sugar caused by common cancer drugs and protect healthy cells in mice from becoming too vulnerable to chemotherapy, according to new research from the University of Southern California.

4 Apr 2017

Researchers discover possible new route to regenerating function lost in diabetes

In people with type I diabetes, insulin-producing beta cells in the pancreas die and are not replaced. Without these cells, the body loses the ability to control blood glucose.

4 Apr 2017

Switching off glucocorticoid signaling in bone could protect against diet-induced metabolic disturbances

A high-calorie diet, even without a high amount of fat, causes bone loss, and both high-calorie and high-fat diets induce excessive fat gain and insulin resistance, a new study conducted in mice finds.

4 Apr 2017

People at high risk for prediabetes could be identified using simple tool

The time to maximal sugar level during an oral glucose tolerance test is associated with higher risk for prediabetes and could give important information about the ability of the pancreas to secrete insulin, according to research presented at the Endocrine Society's 99th annual meeting, ENDO 2017, in Orlando, Fla.

4 Apr 2017

Noninvasive dTMS technique helps obese people lose weight by changing gut microbiota composition

A new study finds that a noninvasive electromagnetic brain stimulation technique helps obese people lose weight, partly by changing the composition of their intestinal bacteria—the so-called gut microbiota.

4 Apr 2017

Glucose News and Research

Scientists discover how insulin-producing cells show differences in age

Study may provide insight into how R-LA promotes death of hepatoma cells

Metabolite produced by intestinal bacteria protects against type 2 diabetes, study shows

Researchers map gene activity to reveal how the liver performs different functions

Overweight, obese workers more likely to take sick leave, study shows

Study compares insulin pump therapy and injections in type 1 diabetes patients during Ramadan fasting

FDA authorizes marketing of first direct-to-consumer GHR tests for certain diseases

HIIT increases glucose metabolism and insulin sensitivity in diabetics, research reveals

Are we sleeping less than we used to?

Cellular markers of aging could reveal how insulin-producing cells begin to fail in type 2 diabetes

Tumor microenvironment poses unique challenges for effective ovarian cancer T-cell therapy

Low normalized grip strength linked to cardiometabolic diseases and disabilities in adults

Liver shows positive response to leptin therapy in patients with partial lipodystrophy, study finds

Study finds cardio-metabolic risk factors even in individuals with normal BMI

Research suggests using combined OGTT and HbA1C tests to screen children at high risk of diabetes

Short-term fasting during chemotherapy may counteract side effects of common cancer drugs

Researchers discover possible new route to regenerating function lost in diabetes

Switching off glucocorticoid signaling in bone could protect against diet-induced metabolic disturbances

People at high risk for prediabetes could be identified using simple tool

Noninvasive dTMS technique helps obese people lose weight by changing gut microbiota composition

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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