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New approach to combination drug design could be applied to disease therapies beyond diabetes

Biomedical engineers at Duke University have shown that the efficacy of a two-pronged type 2 diabetes treatment increases when the drugs are linked by a heat-sensitive tether rather than simply concurrently administered.

27 Aug 2020

University of Illinois to head two of artificial intelligence institutes in the U.S

The National Science Foundation and the U.S. Department of Agriculture's National Institute of Food and Agriculture are announcing an investment of more than $140 million to establish seven artificial intelligence institutes in the U.S. Two of the seven will be led by teams at the University of Illinois, Urbana-Champaign.

27 Aug 2020

Targeting a key gateway can help treat chronic pain, shows study

Something like a quarter of the world's population suffers from chronic pain at some point. As opposed to acute pain – for example, that feeling after hitting your finger with a hammer – chronic pain may not even have a clear cause, and it can linger for years or lifetimes.

27 Aug 2020

Novel cell-based therapy holds promise for obesity and diabetes

Obesity is the main cause of type 2 diabetes and related chronic illnesses that together will kill more people around the globe this year than the Covid-19 coronavirus.

26 Aug 2020

UBC discovery may offer new treatment possibility for women with rare form of ovarian cancer

A recent finding by researchers at the BC Cancer Research Institute and the University of British Columbia may offer a new treatment possibility for people diagnosed with a rare and aggressive form of ovarian cancer.

26 Aug 2020

Studies unravel COVID-19 mysteries

A team from Lawson Health Research Institute and Western University has made significant steps forward in understanding COVID-19 through two back-to-back studies published this week in Critical Care Explorations.

26 Aug 2020

Exosomes: The cancer cell communication mechanism

Professor Deborah Goberdhan speaks to News-Medical about her team's latest research into cancer cells, and the mechanisms they use to communicate.

26 Aug 2020

Synthetic gene fragments from SARS-CoV-2 can help produce accurate diagnostic tests

Researchers at the National Institute of Standards and Technology (NIST) have produced synthetic gene fragments from SARS-CoV-2, the virus that causes COVID-19. This material, which is non-infectious and safe to handle, can help manufacturers produce more accurate and reliable diagnostic tests for the disease.

26 Aug 2020

Forsyth Institute to provide research and development support for saliva-based COVID-19 tests

As a world leader in oral biology and salivary diagnostics, the Forsyth Institute is working with the National Institutes of Health (NIH) Rapid Acceleration of Diagnostics (RADx) initiative as an advisor and critical resource in the effort to develop and eventually deploy millions of accurate, rapid COVID-19 point-of-care tests used daily in schools, colleges, universities, and for testing underserved populations.

26 Aug 2020

Inhaled steroids reduce SARS-CoV-2-related genes in COPD

A new study published on the preprint server medRxiv* aims to explore the effects of treatment with ICS on the expression of specific genes related to SARS-CoV-2 infection in bronchial epithelial cells in a prospective interventional design.

25 Aug 2020

Highly expressed protein in lung cancer cells drives resistance to targeted therapies

A protein highly expressed in lung cancer cells drives resistance to targeted therapies, report researchers at the Medical University of South Carolina in the Journal of Thoracic and Cardiovascular Surgery.

25 Aug 2020

New, low-cost technology for subcutaneous injection of viscous formulations

MIT researchers have developed a simple, low-cost technology to administer powerful drug formulations that are too viscous to be injected using conventional medical syringes.

24 Aug 2020

Researchers identify potential drug target for curtailing cancer metastasis

Researchers led by Ludwig Chicago Co-director Ralph Weichselbaum and Ronald Rock of the University of Chicago have identified in preclinical studies a potential drug target for curtailing cancer metastasis.

24 Aug 2020

Researchers find a new way to slow colon cancer metastasis

When cancer metastasizes and spreads throughout the body, it can severely change the prognosis of the disease. It is estimated that metastasis is responsible for 90 percent of cancer deaths.

24 Aug 2020

RNA-targeting compound restarts a healing factor silenced by heart attack

A heart attack can leave parts of the heart permanently scarred and stiff, resulting in prolonged disability and potential progression toward heart failure. Scientists have studied various ways to repair or regenerate such damaged heart tissue, with limited success.

24 Aug 2020