Preclinical News and Research

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Columbia researchers find way to reawaken potent cancer-fighting molecule in tumor cells

A potent cancer-fighting molecule in our cells can be reawakened by reducing levels of a protein - called SET - that's often found in excess in cancer cells, a new study from Columbia University's Herbert Irving Comprehensive Cancer Center has found.

15 Sep 2016

Single-dose of anibiotic gel could provide easy and safe treatment for common childhood illness

A single-application bioengineered gel, squirted in the ear canal, could deliver a full course of antibiotic therapy for middle ear infections, making treatment of this common childhood illness much easier and potentially safer, finds a preclinical study led by Boston Children's Hospital in collaboration with investigators at Boston Medical Center and Massachusetts Eye and Ear.

15 Sep 2016

Mood stabilizers may decrease negative symptoms in psychiatric patients with specific genotype

A drug prescribed to many patients with schizophrenia or bipolar disorder may decrease negative symptoms for people with a certain variant of the COMT gene, suggests a new study from researchers at Columbia University Medical Center.

14 Sep 2016

New JGU cyclotron to be employed for research into potential applications in medicine

A new particle accelerator is further enhancing the research landscape at Johannes Gutenberg University Mainz.

14 Sep 2016

Graded aerobic treadmill testing useful in evaluating sports-related concussion in children

Graded aerobic treadmill testing is safe, tolerable, and useful in evaluating and managing cases of sports-related concussion in children and adolescents.

13 Sep 2016

Inhibition of RANK signaling pathway could be potential new therapy in breast cancer

Researchers at the Institute of Biomedical Research of Bellvitge, led by Dr. Eva Gonzalez-Suarez, have shown that pharmacological and genetic inhibition of signaling pathway RANK / RANKL leads to a significant reduction in recurrences and metastases in breast cancer in a mouse animal model.

13 Sep 2016

BUAP researchers develop biomaterial that can be printed in 3D for regenerating bone tissue

Researchers at the Autonomous University of Puebla (BUAP) developed a biomaterial with the ability to serve as a support for regenerating bone tissue, which is biodegradable and can be printed in 3D with controlled porosity.

13 Sep 2016

Next-generation advanced translational research preclinical imaging system unveiled by Bruker

Bruker today unveils two new preclinical imaging systems at the World Molecular Imaging Congress 2016 in New York. The new systems are designed to deliver highest performance and improved convenience for routine imaging, and enable novel translational research into the causes, progression, as well as potential diagnosis and treatment of disease.

From Bruker BioSpin Group 9 Sep 2016

Oncovision’s preclinical PET imaging business acquired in agreement with Bruker

PET and SPECT are key molecular imaging technologies for Bruker’s Preclinical Imaging division, allowing Bruker to offer the highest-performance SiPM-PET/SPECT/CT and integrated SiPM-PET/MR imaging systems.

From Bruker BioSpin Group 9 Sep 2016

Novel approach may help combat kidney disease in diabetic patients

A new strategy may help halt the progression of kidney disease in patients with diabetes.

9 Sep 2016

Research could pave way for more effective and safer anti-epilepsy drugs

Columbia University Medical Center researchers have discovered how a new epilepsy drug works, which may lead the way to even more effective and safer medications.

8 Sep 2016

Researchers reveal potential therapeutic treatment for alphavirus infections

Research conducted by Griffith University and Melbourne-based company Paradigm Biopharmaceuticals Limited has uncovered a potential new therapeutic treatment for the global battle against mosquito-borne alphavirus infections, including the debilitating Ross River Virus (RRV) and Chikungunya Virus (CHIKV).

8 Sep 2016

Clinical trial to examine effectiveness of diabetes drug to slow or stop progression of Parkinson's

Type II diabetes and Parkinson's disease may not appear to have much in common but a look below the surface reveals important molecular similarities that provide a potential target for fighting Parkinson's.

8 Sep 2016

MR Solutions steps up sales of cryogen free, pre-clinical range of scanners

MR Solutions continues to grow sales of its cryogen free, pre-clinical range of scanners including its PET-MR and high field MR systems.

8 Sep 2016

ENDRA introduces Nexus 128+ with twice the photoacoustic sensitivity

ENDRA Life Sciences today announced the launch of the Nexus 128+, adding to their preclinical photoacoustic computed tomography (CT) systems that leverage ENDRA’s proprietary 3D imaging technology.

From AXT Pty Ltd 8 Sep 2016

Stealth insulin-producing pig cells may offer solution for treating Type 1 diabetes in humans

University of Alabama at Birmingham researchers are exploring ways to wrap pig tissue with a protective coating to ultimately fight diabetes in humans. The nano-thin bilayers of protective material are meant to deter or prevent immune rejection.

8 Sep 2016

School-based exercises may benefit bone mass, strength in growing children

Moderate to high impact sports such as gymnastics, basketball, or football have been shown to benefit bone mass, structure and strength - with benefits particularly apparent during pre-and early adolescence.

7 Sep 2016

Beta-blockers can help treat bone loss caused by antidepressants in mice

The antidepressant fluoxetine causes bone loss by instructing the brain to send out signals that increase bone breakdown, but a beta-blocker can intercept the signals, a new study in mice has found.

7 Sep 2016

Researchers identify potential new way of treating hypertension

Researchers eyeing first new anti-hypertensive drug treatment strategy in more than 15 years.

6 Sep 2016

University of Arizona could contribute to improved tumor assessment with preclinical PET scanner for simultaneous PET/MRI

Cubresa Inc., a medical imaging company that develops and markets molecular imaging systems, today announced the successful installation of their compact PET scanner called NuPET™ for preclinical PET (Positron Emission Tomography) and MRI (Magnetic Resonance Imaging) in the Department of Medical Imaging at the University of Arizona (UA).

From Cubresa Inc. 1 Sep 2016

Preclinical News and Research

Columbia researchers find way to reawaken potent cancer-fighting molecule in tumor cells

Single-dose of anibiotic gel could provide easy and safe treatment for common childhood illness

Mood stabilizers may decrease negative symptoms in psychiatric patients with specific genotype

New JGU cyclotron to be employed for research into potential applications in medicine

Graded aerobic treadmill testing useful in evaluating sports-related concussion in children

Inhibition of RANK signaling pathway could be potential new therapy in breast cancer

BUAP researchers develop biomaterial that can be printed in 3D for regenerating bone tissue

Next-generation advanced translational research preclinical imaging system unveiled by Bruker

Oncovision’s preclinical PET imaging business acquired in agreement with Bruker

Novel approach may help combat kidney disease in diabetic patients

Research could pave way for more effective and safer anti-epilepsy drugs

Researchers reveal potential therapeutic treatment for alphavirus infections

Clinical trial to examine effectiveness of diabetes drug to slow or stop progression of Parkinson's

MR Solutions steps up sales of cryogen free, pre-clinical range of scanners

ENDRA introduces Nexus 128+ with twice the photoacoustic sensitivity

Stealth insulin-producing pig cells may offer solution for treating Type 1 diabetes in humans

School-based exercises may benefit bone mass, strength in growing children

Beta-blockers can help treat bone loss caused by antidepressants in mice

Researchers identify potential new way of treating hypertension

University of Arizona could contribute to improved tumor assessment with preclinical PET scanner for simultaneous PET/MRI

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