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Fasting and ketogenic diet reveal new vulnerability of pancreatic tumors to existing cancer drug

Researchers examine the role of fasting and ketogenesis in regulating protein synthesis and its potential implications for cancer therapy.

21 Aug 2024

Review explores the use of medicinal plants against women's diseases in the rural communities of Pakistan

Researchers review the application and utility of traditional medicinal plants in treating gynecological health issues in Pakistan.

21 Aug 2024

Spatial transcriptomics unlocks malaria's liver stage secrets

For the malaria parasite to reach the blood of its human host, it must first enter the liver, where only a small number of parasites differentiate and replicate for upwards of seven days, making it a bottleneck in the parasite's lifecycle. This bottleneck makes the liver stage an optimal target for effective and long-lasting vaccines against the disease. Using Spatial Transcriptomics and single-cell RNA-sequencing technologies, researchers at Stockholm University have for the first time managed to create a spatio-temporal map of malaria infection in the mouse liver. A study that was recently published in Nature Communications.

21 Aug 2024

UQ research could lead to a more effective treatment for bladder cancer

University of Queensland research could lead to a more effective immunotherapy treatment against bladder cancer.

20 Aug 2024

Engineered heart tissues uncover new mechanisms in lupus-related heart damage

Cardiovascular disease is the leading cause of death in patients suffering from lupus, an autoimmune disease in which our immune system attacks our own tissues and organs, the heart, blood, lung, joints, brain, and skin.

20 Aug 2024

UC Davis researchers unveil pathway for Salmonella's gut invasion

How do bad bacteria find entry points in the body to cause infection? This question is fundamental for infectious disease experts and people who study bacteria.

20 Aug 2024

Self-guided cognitive behavioral therapy app reduces anxiety in young adults

Researchers at Weill Cornell Medicine and NewYork-Presbyterian found that a self-guided cognitive behavioral therapy (CBT) app, called Maya, significantly reduced anxiety in young adults struggling with mental health challenges.

20 Aug 2024

Exploring gene silencing mechanisms for improved RNAi therapeutics

RNA interference (RNAi) therapeutics have garnered significant attention in clinical research due to their potential for treating various diseases, including genetic disorders, viral infections and cancer.

20 Aug 2024

AI tools accelerate understanding of cardiac arrhythmia risks in lung cancer treatment

Researchers from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, have used artificial intelligence tools to accelerate the understanding of the risk of specific cardiac arrhythmias when various parts of the heart are exposed to different thresholds of radiation as part of a treatment plan for lung cancer.

20 Aug 2024

Progress and future directions in esophageal cancer screening in China

Esophageal cancer, a highly aggressive malignancy originating in the esophageal epithelium, poses significant public health challenges in China, where it ranks sixth in incidence and fifth in mortality among cancers.

20 Aug 2024

Exploring targeted therapies in the complex landscape of multiple myeloma

Multiple myeloma (MM) is a complex hematological malignancy with significant unmet needs. While conventional therapies have significantly improved patient survival, the disease remains incurable.

20 Aug 2024

Advances in precision medicine enhance cancer immunotherapy

The field of precision medicine, especially in the context of cancer immunotherapy, has seen significant advancements in recent years.

20 Aug 2024

Low-cost videoscopes show promise for screening HPV-associated oropharyngeal cancers

The rise in the incidence of oropharyngeal squamous cell carcinomas (OPSCCs) linked to human papillomavirus (HPV)-16 infection has become notable, surpassing cervical high-risk HPV infections by 2019.

20 Aug 2024

Study links gut microbe depletion to lifelong respiratory allergies

Researchers at the University of British Columbia have shown for the first time how and why the depletion of microbes in a newborn's gut by antibiotics can lead to lifelong respiratory allergies.

20 Aug 2024

Precision medicine enhances prostate cancer treatment with genetic profiling

Men with metastatic castration-resistant prostate cancer should be treated primarily with second-generation hormone drugs, which offer better treatment response and longer life expectancy than chemotherapy.

20 Aug 2024

Revolutionary platelet score offers better risk assessment for heart attacks

Platelets are circulating cell fragments known to clump up and form blood clots that stop bleeding in injured vessels.

20 Aug 2024

How the MIND diet may protect against dementia

Researchers utilize transcriptomic data to examine the protective effects of the MIND diet in reducing the risk of dementia and slowing cognitive decline.

20 Aug 2024

Researchers reveal impact of genetic ancestry on breast cancer risk and cell diversity

Researchers map the diverse cell types present in healthy breast tissue to elucidate the role of genetic ancestry in breast cancer risk.

20 Aug 2024

New project aims to study the combination of two therapies for pediatric brain cancer

Natasha Sheybani, assistant professor of biomedical engineering at the University of Virginia School of Engineering, will collaborate with researchers at Children's National Hospital to study the combination of two therapies for pediatric brain cancer.

19 Aug 2024