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The potential of Sofosbuvir against COVID-19 neurological symptoms

Researchers discuss how SARS-CoV-2 infects cortical neurons and damages their synapses that form the connection between brain cells.

25 Nov 2022

BW.1- a new Omicron subvariant that escapes immunity

Researchers reports the presence of mutations that aid in immune escape in the BW.1 Omicron subvariant.

25 Nov 2022

World Antimicrobial Awareness Week 2022: What is the burden of antimicrobial resistance?

As part of World Antimicrobial Resistance Week 2022, News-Medical speaks to Dr. Tomislav Meštrović about his new research discussing the burden of bacterial antimicrobial resistance in the WHO European region, as well as about how we can prevent antimicrobial resistance together.

24 Nov 2022

Exploring clinical characteristics and outcomes of hospitalized COVID-19 patients

Researchers described the clinical characteristics and outcomes of patients hospitalized with coronavirus disease 2019 (COVID-19) in the Netherlands.

24 Nov 2022

Newly developed healthcare app can help reduce body weight

Behavior therapy is a well-known and effective treatment for obesity. But now, researchers from Japan have found that behavior therapy can be successfully implemented using a smartphone healthcare app.

24 Nov 2022

The relationship between neutralization levels and observed efficacies against asymptomatic and symptomatic infection of ten COVID-19 vaccines

Researchers determined whether neutralizing antibody levels were predictive of the efficacy of fractional vaccine doses against SARS-CoV-2 infection.

24 Nov 2022

Study aims to develop broad-spectrum antivirals against SARS-CoV-2 via drug repurposing strategies

This study aims to determine which FDA-approved compound(s) can be repurposed as a broad-spectrum antiviral drug(s) against SARS-CoV-2 and variants.

24 Nov 2022

High-risk stage III-IV melanoma patients treated with pembrolizumab report better quality of life

Patients with high-risk stage III-IV melanoma who received pembrolizumab after their surgery reported a better quality of life than patients who received the previous standard-of-care treatment with either ipilimumab or high-dose interferon.

23 Nov 2022

Morphine does not reduce worst breathlessness, study finds

Sometimes healthcare professionals treat patients with opioids such as morphine to relieve symptoms, but there has been a lack of evidence as to whether this helps with severe chronic breathlessness.

23 Nov 2022

Bivalent mRNA vaccines could enhance protective efficacy against COVID-19

A new study presents evidence suggestive of restored or increased efficacy from changing the formulation of COVID-19 vaccines to a bivalent one.

23 Nov 2022

The safety and immunogenicity of a fourth dose of NVX-CoV2373

Researchers assessed the immunogenicity and safety of a fourth homologous boost dose of a recombinant SARS-CoV-2 spike protein vaccine called NVX-CoV2373.

23 Nov 2022

Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

In a recent study posted to the bioRxiv* preprint server, researchers in China demonstrated the efficacy of three messenger ribonucleic acid (mRNA) technology-based Monkeypox virus (MPXV) vaccines in combating a lethal Vaccinia virus (VACV) challenge in mice models.

22 Nov 2022

Plant-based monoclonal antibody increases potency of antibody cocktail against SARS-CoV-2 Omicron variant

A novel mAb against the SARS-CoV-2 RBD through a hybridoma technique, followed by chimerization and expression in plants.

22 Nov 2022

Family involvement in psychosis treatment leads to better patient outcomes, research says

According to new research from Boston Medical Center, family involvement in psychosis treatment leads to better patient outcomes.

22 Nov 2022

Remdesivir appears to make a big difference in Japanese patients with COVID-19

The COVID-19 pandemic has led to an explosion of clinical research resulting in the development of a variety of vaccines and treatments, although the efficacy of some remains controversial.

22 Nov 2022

Effects of implemented vaccine rollout strategies on spread of SARS-CoV-2, subsequent global burden of disease, and emergence of novel variants

Researchers conducted a retrospective analysis to investigate the impact of vaccine-sharing strategies on the heterogenous global distribution of COVID-19 vaccines.

22 Nov 2022

Creating New Targeted Antibacterial Products to Help Tackle Antimicrobial Resistance

We speak to Matthew Dunne, Director for Drug Discovery at Micreos Pharmaceuticals, about the importance of creating new targeted antibacterial products.

22 Nov 2022

US experienced higher COVID-19 mortality during delta and omicron waves

A recent study estimates coronavirus disease 2019-related mortality and excess all-cause mortality in the US and 20 peer countries during the delta and omicron waves of infection.

22 Nov 2022

Exploring antibiotic resistance in the EU

Antibiotic resistance is one of the greatest threats to global human health and to development.

22 Nov 2022

The vaginal microbiome through the lens of systems biology

A new paper recently published online in Trends in Microbiology journal reviews the systems biology approach to explore the vaginal microbiome (VMB), helping to understand its composition and function and the mechanisms by which it interacts with the host.

22 Nov 2022

Efficacy News and Research

The potential of Sofosbuvir against COVID-19 neurological symptoms

BW.1- a new Omicron subvariant that escapes immunity

World Antimicrobial Awareness Week 2022: What is the burden of antimicrobial resistance?

Exploring clinical characteristics and outcomes of hospitalized COVID-19 patients

Newly developed healthcare app can help reduce body weight

The relationship between neutralization levels and observed efficacies against asymptomatic and symptomatic infection of ten COVID-19 vaccines

Study aims to develop broad-spectrum antivirals against SARS-CoV-2 via drug repurposing strategies

High-risk stage III-IV melanoma patients treated with pembrolizumab report better quality of life

Morphine does not reduce worst breathlessness, study finds

Bivalent mRNA vaccines could enhance protective efficacy against COVID-19

The safety and immunogenicity of a fourth dose of NVX-CoV2373

Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

Plant-based monoclonal antibody increases potency of antibody cocktail against SARS-CoV-2 Omicron variant

Family involvement in psychosis treatment leads to better patient outcomes, research says

Remdesivir appears to make a big difference in Japanese patients with COVID-19

Effects of implemented vaccine rollout strategies on spread of SARS-CoV-2, subsequent global burden of disease, and emergence of novel variants

Creating New Targeted Antibacterial Products to Help Tackle Antimicrobial Resistance

US experienced higher COVID-19 mortality during delta and omicron waves

Exploring antibiotic resistance in the EU

The vaginal microbiome through the lens of systems biology

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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