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Super-resolution imaging and size analysis of SARS-CoV-2 virus particles

Researchers from the University of Oxford and the University of Warwick have collaborated to develop a method to better understand and evaluate these pleiomorphisms.

28 Sep 2021

Researchers discover protein previously unknown to be involved in SARS-CoV-2 infection

Researchers in the UK and Germany have provided evidence for a novel mechanism by which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – binds to human host cells.

27 Sep 2021

A new SARS-CoV-2 variant (B.1.1.523) capable of escaping immune protections

A new study describes a new variant that possesses a novel combination of various concerning mutations at the spike region.

27 Sep 2021

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

A new review article investigates the clinical and viral characteristics, pathogenesis, as well as human genetic basis associated with COVID-19.

27 Sep 2021

Researchers develop new method for rapidly detecting SARS-CoV-2 RNA

DTU-researchers develop a novel method for rapidly detecting SARS-CoV-2 RNA that may also be designed to detect other diseases.

27 Sep 2021

Characterization of SARS-CoV-2 infections diagnosed after mRNA BNT162b2 vaccination

A team from the National Institute for Infectious Diseases “L. Spallanzani” (INMI) has recently reported their study on 94 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections (47.9% symptomatic, 52.1% asymptomatic) that occurred after the first or second vaccine dose against SARS-CoV-2 in the Lazio region (Central Italy).

27 Sep 2021

Design of peptide vaccine for SARS-CoV-2

In a recent study, researchers from the US identified two immunogenic non-structural proteins - PLpro and RdRp - from immunodominant gene regions ORF1ab, ORF3a and ORF9b as potential targets for a vaccine against SARS-CoV-2.

27 Sep 2021

Machine learning pinpoints genes that enable plants to grow more with less fertilizer

Machine learning can pinpoint "genes of importance" that help crops to grow with less fertilizer, according to a new study published in Nature Communications. It can also predict additional traits in plants and disease outcomes in animals, illustrating its applications beyond agriculture.

25 Sep 2021

Researchers describe a novel role for hnRNP E1 protein in binding DNA in the nucleus

Cancer is a devastating disease and is the second leading cause of death in the U.S. One of the hallmarks of cancer is genomic instability, or the tendency to accumulate mutations and damage to the DNA that leads to genome alterations during cell division.

25 Sep 2021

Research explores the evolution and function of human growth hormone receptor gene

A new study delves into the evolution and function of the human growth hormone receptor gene and asks what forces in humanity's past may have driven changes to this vital piece of DNA.

25 Sep 2021

AI technique could lead to new ways to predict cancer prognosis and treatment response

Researchers and data scientists at UT Southwestern Medical Center and MD Anderson Cancer Center have developed an artificial intelligence technique that can identify which cell surface peptides produced by cancer cells called neoantigens are recognized by the immune system.

24 Sep 2021

Study identifies master regulator behind the development of antibody-producing cells

The master regulator behind the development of antibody-producing cells has been identified in a study by investigators at Weill Cornell Medicine. The findings provide new insight into the inner workings of the immune system and may help understand how tissues develop and how certain cancers arise.

24 Sep 2021

Infections impact blood vessel repair within the meninges following TBI or other cerebrovascular injuries

Viral Infection Slows Blood Vessel Repair After TBI: Seven days after mTBI, the blood vessels (stained in red) in the tissues around the brain are not completely repaired. A marker for intact vessels was used (labeled in green) to distinguish fully functional blood vessels (yellow) from ones that are still damaged (red).McGavern Lab, NINDS

24 Sep 2021

Exploring the polymerase of poxviruses at an atomic level

Poxviruses have found a unique way of translating their genes into proteins in the infected organism. A team of researchers from Würzburg shows for the first time how the molecular machinery involved works at an atomic level.

24 Sep 2021

Design of mRNA vaccines to combat COVID-19

A recent review study discusses fundamental concepts in the successful delivery of nucleic acids in therapeutics.

23 Sep 2021

Genome modeling framework for coronavirus pathogenicity prediction

Recent machine learning techniques have allowed viral genome sequencing to be utilized in a predictive capacity.

23 Sep 2021

SARS-CoV-2 genome signature leads to replicative advantage in presence of Remdesivir

A new study indicates that low-level resistance of SARS-CoV-2 to remdesivir is not widespread and dissimilar to other RNA viruses revealing evolutionary predictability of this pandemic virus.

22 Sep 2021

SARS-CoV-2 delta variant has higher viral RNA levels and increased infectivity, suggests study

The study found that the delta and epsilon variants exhibited significantly higher infectivity than alpha, with delta containing approximately six times as much infectious virus for the same amount of RNA.

22 Sep 2021

Study findings could lead to novel ways to overcome tumor resistance to immunotherapies

Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different "program" that makes them less effective than immune cells in patients whose cancers respond to these immune treatments, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy.

22 Sep 2021

Scientists use statistical mechanics to make sense of DNA folding

At more than 2 meters long, the human DNA molecule uses intricate folding patterns to fit into cells while locally unfolding to express genes. Such phenomena, however, are difficult to measure in experiments, and theoretical frameworks explaining them continue to be at odds with one another.

22 Sep 2021

Genome News and Research

Super-resolution imaging and size analysis of SARS-CoV-2 virus particles

Researchers discover protein previously unknown to be involved in SARS-CoV-2 infection

A new SARS-CoV-2 variant (B.1.1.523) capable of escaping immune protections

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

Researchers develop new method for rapidly detecting SARS-CoV-2 RNA

Characterization of SARS-CoV-2 infections diagnosed after mRNA BNT162b2 vaccination

Design of peptide vaccine for SARS-CoV-2

Machine learning pinpoints genes that enable plants to grow more with less fertilizer

Researchers describe a novel role for hnRNP E1 protein in binding DNA in the nucleus

Research explores the evolution and function of human growth hormone receptor gene

AI technique could lead to new ways to predict cancer prognosis and treatment response

Study identifies master regulator behind the development of antibody-producing cells

Infections impact blood vessel repair within the meninges following TBI or other cerebrovascular injuries

Exploring the polymerase of poxviruses at an atomic level

Design of mRNA vaccines to combat COVID-19

Genome modeling framework for coronavirus pathogenicity prediction

SARS-CoV-2 genome signature leads to replicative advantage in presence of Remdesivir

SARS-CoV-2 delta variant has higher viral RNA levels and increased infectivity, suggests study

Study findings could lead to novel ways to overcome tumor resistance to immunotherapies

Scientists use statistical mechanics to make sense of DNA folding

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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