Preclinical News and Research

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Monoclonal antibody removes brain amyloid plaques in patients with Alzheimer's disease

Scientists at Neurimmune today described results from the Phase 1b PRIME clinical trial of the monoclonal antibody aducanumab.

1 Sep 2016

New study suggests most American adults with depression receive no treatment

New findings suggest that most Americans with depression receive no treatment, while raising the possibility that overtreatment of depression is also widespread.

29 Aug 2016

Leading Chikungunya vaccine in clinical trial phase 2

With the first patient vaccinated, a Phase 2 clinical trial of a promising prophylactic vaccine candidate against Chikungunya fever has now commenced. The product is the most advanced Chikungunya vaccine candidate globally and is developed by the Austrian biotech company Themis Bioscience GmbH.

29 Aug 2016

Can-Fite BioPharma reports financial results, provides update on drug development programs

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs being developed to treat inflammatory diseases, cancer and sexual dysfunction, today reported financial results for the six months ended June 30, 2016 and updates on its drug development programs.

27 Aug 2016

Novel small-molecule Wnt inhibitor may provide new treatment option for colorectal cancer patients

A team including the National Cancer Center, the RIKEN Center for Life Science Technologies , and Carna Biosciences Inc., has jointly announced the development of a novel small-molecule Wnt inhibitor named NCB-0846.

26 Aug 2016

New camera technology paired with electron microscope allows biologists to see tiny cellular components

Using a new, lightning-fast camera paired with an electron microscope, Columbia University Medical Center scientists have captured images of one of the smallest proteins in our cells to be "seen" with a microscope.

26 Aug 2016

New UCF technology for destroying metastatic breast cancer cells licensed for clinical trials

A University of Central Florida cancer researcher has discovered a way to kill spreading breast cancer cells and her new technology has generated a licensing agreement that will accelerate the therapy's path to clinical trials.

25 Aug 2016

Optimal doses of omega-3 fatty acids appear to improve outcomes from traumatic brain injury

The treatment of concussions and traumatic brain injury (TBI) is a clinical challenge. Clinical studies thus far have failed to identify an effective treatment strategy when a combination of targets controlling aspects of neuroprotection, neuroinflammation, and neuroregeneration is needed.

25 Aug 2016

New imaging technique may help detect amyloid-related heart failure

A type of heart failure caused by a build-up of amyloid can be accurately diagnosed and prognosticated with an imaging technique, eliminating the need for a biopsy, according to a multicenter study led by researchers at Columbia University Medical Center.

24 Aug 2016

New study may offer vital clues to understanding how Zika virus affects the developing brain

In a very severe, genetic form of microcephaly, stem cells in the brain fail to divide, according to a new Columbia University Medical Center study that may provide important clues to understanding how the Zika virus affects the developing brain.

24 Aug 2016

Injecting omega-3 fatty acid reduces brain damage in neonatal mouse model of stroke

Researchers from Columbia University Medical Center found that omega-3 fatty acids reduced brain damage in a neonatal mouse model of stroke.

23 Aug 2016

QUT molecular microbiologist developing new therapies to beat bacterial superbugs

QUT molecular microbiologist Makrina Totsika is at the forefront of research to develop new therapies to beat multi-drug resistant bacteria.

22 Aug 2016

Men experience greater pain relief than women after smoking marijuana, study finds

Researchers from Columbia University Medical Center found that men had greater pain relief than women after smoking marijuana.

19 Aug 2016

Mayo Clinic, Geroscience Network researchers aim to accelerate pace of aging research

Mayo Clinic, along with other members of the Geroscience Network, has published six manuscripts that map strategies for taking new drugs that target processes underlying aging into clinical trials.

17 Aug 2016

Could nanotechnology turn the cancer cell suicide switch back on? An interview with Professor Dipanjan Pan

Before I explain the discovery, I would take a step back and explain an interesting event that takes place in the cancer cells. Normal cells follow a rapid and irreversible process to efficiently eradicate dysfunctional cells. This is a natural process by which damaged cells commit ‘suicide’. This process is known as apoptosis or programmed cell death.

15 Aug 2016

NIH funds collaborative project to develop better vaccine adjuvants for many diseases

Dr. Qizhi Cathy Yao, professor of surgery, molecular virology and microbiology, and pathology & immunology at Baylor College of Medicine, has been awarded a National Institutes of Health grant to fund a collaborative project with Molecular Express, Inc.

12 Aug 2016

TUM scientists isolate and archive cultured bacterial strains from mouse microbiome

Mouse models are extensively used in pharmaceutical and medical research, and it is known that the communities of microbes in their intestine can have a significant impact on the research output.

12 Aug 2016

NIH researchers design new set of assays for initial screening of patients with Fragile X syndrome

Fragile X syndrome, the most common heritable cause of intellectual disability and a frequent cause of autism, is characterized by abnormalities of the FMR1 gene that are difficult to analyze.

12 Aug 2016

BCL-2 inhibitor shows promise in AML patients

Patients whose acute myelogenous leukemia (AML) had relapsed or was resistant to chemotherapy and those who were deemed unable to tolerate chemotherapy experienced responses to the selective BCL-2 inhibitor venetoclax (Venclexta), with complete remissions in some, according to phase II clinical trial data.

12 Aug 2016

MR Solutions wins prestigious Queen’s Award for Enterprise

MR Solutions has received the prestigious Queen’s Award for Enterprise from the Lord Lieutenant of Surrey at their Guildford headquarters in July to mark their achievement for innovation.

From MR Solutions 10 Aug 2016

Preclinical News and Research

Monoclonal antibody removes brain amyloid plaques in patients with Alzheimer's disease

New study suggests most American adults with depression receive no treatment

Leading Chikungunya vaccine in clinical trial phase 2

Can-Fite BioPharma reports financial results, provides update on drug development programs

Novel small-molecule Wnt inhibitor may provide new treatment option for colorectal cancer patients

New camera technology paired with electron microscope allows biologists to see tiny cellular components

New UCF technology for destroying metastatic breast cancer cells licensed for clinical trials

Optimal doses of omega-3 fatty acids appear to improve outcomes from traumatic brain injury

New imaging technique may help detect amyloid-related heart failure

New study may offer vital clues to understanding how Zika virus affects the developing brain

Injecting omega-3 fatty acid reduces brain damage in neonatal mouse model of stroke

QUT molecular microbiologist developing new therapies to beat bacterial superbugs

Men experience greater pain relief than women after smoking marijuana, study finds

Mayo Clinic, Geroscience Network researchers aim to accelerate pace of aging research

Could nanotechnology turn the cancer cell suicide switch back on? An interview with Professor Dipanjan Pan

NIH funds collaborative project to develop better vaccine adjuvants for many diseases

TUM scientists isolate and archive cultured bacterial strains from mouse microbiome

NIH researchers design new set of assays for initial screening of patients with Fragile X syndrome

BCL-2 inhibitor shows promise in AML patients

MR Solutions wins prestigious Queen’s Award for Enterprise

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