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Increased skin-to-skin time linked to better neurodevelopment

Skin-to-skin cuddling with a parent has lasting cognitive benefits for premature babies, according to a new Stanford Medicine study. Preemies who received more skin-to-skin contact, also known as kangaroo care, while hospitalized as newborns were less likely to be developmentally delayed at 1 year of age, the study found.

8 Aug 2024

Amyloid immunotherapy for early Alzheimer's: Promising but fraught with challenges

Researchers highlighted the complexities of using amyloid immunotherapy for early Alzheimer's disease, discussing its clinical benefits, challenges, and broader health implications. Despite some positive results, concerns over adverse effects, trial biases, and cost hinder widespread adoption.

7 Aug 2024

Research finds synaptic strength key to maintaining memory in old age

Over the course of life, memory fades with varying degrees, robbing older people of the ability to recollect personal experiences.

7 Aug 2024

New stem cell therapy for heart failure undergoing U.S. clinical trials

A new stem cell therapy for heart failure is being tested in patients at the University of Louisville and UofL Health.

7 Aug 2024

High blood sugar at stroke admission linked to poor prognosis

Having higher than usual blood sugar levels at the time of hospital admission for an ischemic stroke significantly increases the risk of a poor functional prognosis or death within three months of the stroke.

7 Aug 2024

USC Norris to open state-of-the-art cancer center in Newport Beach with advanced radiation therapy

USC Norris Comprehensive Cancer Center, part of Keck Medicine of USC, will open a Newport Beach location offering the latest advancements in radiation therapy and diagnostic imaging.

7 Aug 2024

Decoding glioblastoma: New insights into molecular subtypes and mesenchymal transition mechanisms

Glioblastoma multiforme (GBM) stands as a formidable adversary in oncology, characterized by its molecular complexity and relentless progression.

7 Aug 2024

KAUST researchers uncover LINE-1 RNA’s role in triggering bone repair

Around half of the human genome is composed of DNA fragments originating from ancient viruses. These "transposable elements" (TEs) are now known to play various roles in modulating gene expression and disease development.

7 Aug 2024

Current challenges in defining, measuring, and treating MS-related fatigue

Kessler Foundation research scientist John DeLuca, PhD, has published a significant clinical article in Journal of Neurology, shedding light on the elusive nature of fatigue in multiple sclerosis (MS) and its implications for treatment.

7 Aug 2024

New research uncovers mechanisms behind heart damage from CTLA-4 blockade

Cytotoxic T-lymphocyte antigen 4 (CTLA-4) is a protein receptor on T immune cells that prevents the cells from killing other cells, such as cancer cells.

7 Aug 2024

From discovery to approval: Vorasidenib approved by FDA for treatment of IDH-mutant gliomas

A new drug for treatment of a type of brain cancer, called IDH-mutant low-grade glioma, was approved Aug. 6 by the U.S. Food and Drug Administration (FDA).

7 Aug 2024

Understanding the age gap in leukemia survival rates

Acute lymphoblastic leukemia (ALL) affects both children and adults, but children have better chances to be cured, with long-term survival rates over 85% compared to 50-75% in adults. Scientists at St. Jude Children's Research Hospital conducted a comprehensive study to understand the biological causes driving this difference. The work, published today in the Journal of Clinical Oncology, provides a blueprint for understanding B-cell acute lymphoblastic leukemia (B-ALL), the most common form of the disease.

7 Aug 2024

Study advances understanding of complex neurological disorder

To effectively treat a disease or disorder, doctors must first know the root cause. Such is the case for developmental and epileptic encephalopathies (DEEs), whose root causes can be hugely complex and heterogeneous. Scientists at St. Jude Children's Research Hospital demonstrated the value of DNA methylation patterns for identifying the root cause of DEEs, showing specific gene methylation and genome-wide methylation "episignatures" can help identify the genes that cause DEE. The findings were published today in Nature Communications.

7 Aug 2024

FDA approves vorasidenib for Grade 2 gliomas with IDH mutations

Vorasidenib has been approved by the U.S. Food and Drug Administration (FDA) for patients with Grade 2 gliomas with IDH1 or IDH2 mutations.

6 Aug 2024

Analyzing the impact of heart disease treatments on patients with CHIP

Nicholas A. Marston, MD, MPH, of the TIMI Study Group and Carl J. and Ruth Shapiro Cardiovascular Center at Brigham and Women's Hospital, is the corresponding author of a paper published in Nature Medicine, "Clonal hematopoiesis, cardiovascular events and treatment benefit in 63,700 individuals from five TIMI randomized trials."

6 Aug 2024

High initial drug doses may reduce cancer drug resistance

On July 28, 2024, Mikhail V. Blagosklonny M.D., Ph.D., from Roswell Park Comprehensive Cancer Center published a new editorial in Volume 16, Issue 14 of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), entitled, "Targeted cancer therapy: the initial high concentration may slow down the selection for resistance."

6 Aug 2024