Clinical Trial News and Research

RSS

Study could aid in the development of adaptive DBS treatments for obsessive-compulsive disorder

In a small study, researchers funded by the National Institutes of Health captured more than 1,000 hours of brain recordings from patients with OCD in the clinic and at home.

9 Dec 2021

Biologic agent dupilumab effective in improving asthma exacerbations and lung function, study shows

A new medication has been added to the treatment options for children with moderate-to-severe asthma. In a late-stage clinical trial, the biologic agent dupilumab reduced the rate of severe asthma attacks and improved lung function and asthma control for children ages 6 to 11.

9 Dec 2021

Gene therapy and diabetes drug may be treatments for late-onset retinal degeneration

Scientists have discovered that gene therapy and the diabetes drug metformin may be potential treatments for late-onset retinal degeneration (L-ORD), a rare, blinding eye disease.

9 Dec 2021

Positive results from Phase 3 study of Medicago’s plant-based COVID-19 vaccine candidate announced

Medicago, a biopharmaceutical company headquartered in Quebec City, and GlaxoSmithKline today announce positive efficacy and safety results from the global Phase 3 placebo-controlled efficacy study of Medicago’s plant-based COVID-19 vaccine candidate in combination with GSK’s pandemic adjuvant, conducted in over 24,000 subjects, adults 18 years and above, across six countries.

9 Dec 2021

High-dose intravenous iron reduces heart attacks in hemodialysis patients

A new paper in Cardiovascular Research, published by Oxford University Press, indicates that iron treatments may reduce heart attacks in patients experiencing kidney failure undergoing dialysis.

8 Dec 2021

Study identifies several proteins that protect against disease development

Inflammatory processes are associated with a large range of human diseases, including rheumatic diseases and allergies. Protein biomarkers are measurable molecules that can have a prognostic value in patients, be used to diagnose disease, or indicate severity of disease.

8 Dec 2021

Electronic nicotine delivery systems may help some people stop smoking cigarettes

Electronic cigarettes with cigarette-like nicotine delivery may help some people stop smoking cigarettes, according to a new study by Penn State College of Medicine and Virginia Commonwealth University researchers.

8 Dec 2021

Length of the lipid chains predicts a person's risk for Parkinson’s disease

Whether or not someone develops Parkinson's disease may be a game of nanometers.

7 Dec 2021

Stand Up To Cancer - An Interview with Chris Draft

In this inspiring interview, we speak to former NFL player Chris Draft about lung cancer, and how he has partnered with SU2C to help raise awareness surrounding it.

7 Dec 2021

Novel monoclonal antibody could help revolutionize treatment of children with high-risk neuroblastoma

Survival rates increased about 20% for children with high-risk neuroblastoma enrolled in a St. Jude Children’s Research Hospital clinical trial that included a novel monoclonal antibody produced onsite. The findings appeared today in the Journal of Clinical Oncology.

6 Dec 2021

UC San Diego participates in the expansion of Parkinson’s Progression Markers Initiative

After a decade of pioneering research, the Parkinson's Progression Markers Initiative by The Michael J. Fox Foundation for Parkinson's Research will see a major expansion.

6 Dec 2021

New protein variant underlies the ability of gastric cancers to resist chemotherapy

A new protein variant underlies the ability of gastric cancers to resist an otherwise effective family of chemotherapy drugs, according to a study by a multidisciplinary team at Weill Cornell Medicine. The results suggest a treatment strategy that could improve the prognoses of many patients with cancer.

6 Dec 2021

Safety and immunogenicity of SARS-CoV-2 recombinant spike protein vaccine

Researchers have presented the results of phase 1 and phase 2 clinical trials of a SARS-CoV-2 recombinant spike protein vaccine (Abdala).

6 Dec 2021

$3.4 million funding to explore how COVID-19 has affected the health of people with preexisting chronic conditions

Gayenell Magwood, Ph.D., of the Medical University of South Carolina (MUSC) has received more than $3.4 million in funding from the National Institute of Nursing Research (NINR) to investigate how COVID-19 has affected the health and quality of life of Black South Carolinians with preexisting chronic conditions and their caregivers.

6 Dec 2021

Targeting the brain should be the focus of ALS therapy, not just spinal cord

The brain is indeed a target for treating ALS (amyotrophic lateral sclerosis), Northwestern Medicine scientists have discovered.

4 Dec 2021

Daytime meals may reduce adverse metabolic effects associated with night shift work

A small clinical trial supported by the National Institutes of Health has found that eating during the nighttime—like many shift workers do—can increase glucose levels, while eating only during the daytime might prevent the higher glucose levels now linked with a nocturnal work life.

4 Dec 2021

New nanoparticle adjuvant could help make vaccines more powerful

A common strategy to make vaccines more powerful is to deliver them along with an adjuvant - a compound that stimulates the immune system to produce a stronger response.

3 Dec 2021

New blood test provides more accurate, faster diagnosis of HPV-associated head and neck cancer

Researchers at Mass Eye and Ear and Mass General Hospital have developed a blood test, or liquid biopsy, for head and neck cancer associated with the human papilloma virus (HPV) that was shown in a new study to be more accurate, faster and cheaper than conventional testing methods.

2 Dec 2021

Fast-tracked human stroke drug may also be a safe and powerful defense against dementia

A human stroke drug, fast-tracked by the Food and Drug Administration and soon entering Phase 3 clinical trials, shows intriguing signs that it might also be a safe and powerful defense against Alzheimer's and other forms of dementia.

1 Dec 2021

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

1 Dec 2021

Clinical Trial News and Research

Study could aid in the development of adaptive DBS treatments for obsessive-compulsive disorder

Biologic agent dupilumab effective in improving asthma exacerbations and lung function, study shows

Gene therapy and diabetes drug may be treatments for late-onset retinal degeneration

Positive results from Phase 3 study of Medicago’s plant-based COVID-19 vaccine candidate announced

High-dose intravenous iron reduces heart attacks in hemodialysis patients

Study identifies several proteins that protect against disease development

Electronic nicotine delivery systems may help some people stop smoking cigarettes

Length of the lipid chains predicts a person's risk for Parkinson’s disease

Stand Up To Cancer - An Interview with Chris Draft

Novel monoclonal antibody could help revolutionize treatment of children with high-risk neuroblastoma

UC San Diego participates in the expansion of Parkinson’s Progression Markers Initiative

New protein variant underlies the ability of gastric cancers to resist chemotherapy

Safety and immunogenicity of SARS-CoV-2 recombinant spike protein vaccine

$3.4 million funding to explore how COVID-19 has affected the health of people with preexisting chronic conditions

Targeting the brain should be the focus of ALS therapy, not just spinal cord

Daytime meals may reduce adverse metabolic effects associated with night shift work

New nanoparticle adjuvant could help make vaccines more powerful

New blood test provides more accurate, faster diagnosis of HPV-associated head and neck cancer

Fast-tracked human stroke drug may also be a safe and powerful defense against dementia

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Driving innovation in Korean drug development

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer