Efficacy News and Research

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Potent hypervalent nanoparticles against HIV, Lassa and SARS-CoV-2 variants

In a recent study published in the journal Advanced Science, researchers developed molecularly imprinted nanoparticles (nanoMIPs) with broad-spectrum activity against lethal viruses.

21 Nov 2022

Johns Hopkins experts receive PCORI funding to optimize antibiotic therapy for gram-negative bloodstream infections

To study how best to treat potentially dangerous infections commonly seen in people with underlying chronic medical conditions, two infectious disease experts at Johns Hopkins Medicine have been awarded $10 million in research funding over five years by the Patient-Centered Outcomes Research Institute.

21 Nov 2022

Comprehensive analysis outlines the potential toxicities of antibody drug conjugates

Over the past two decades, numerous complex cancer therapies called antibody drug conjugates (ADCs) have been tested in clinical trials and approved for use in patients.

21 Nov 2022

New method for isolating Omicron subvariant and evaluating resistance to therapeutic and vaccine-elicited antibodies

Researchers demonstrated a viral amplification procedure to isolate the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants.

21 Nov 2022

WHO‒recommended alcohol-based hand rub formulations show efficacy against Monkeypox virus

Researchers demonstrated the efficacy of two World Health Organization (WHO)‒recommended alcohol-based hand rub solutions to inactivate the monkeypox virus (MPXV).

21 Nov 2022

CAR T-cell therapy in colorectal cancer

Researchers assessed the efficacy of CAR T-cells in the immunotherapy of colorectal cancer.

21 Nov 2022

Rutgers scientists develop new approach to effectively shut down viral infections

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.

20 Nov 2022

In our rapidly changing world, parasites and vectors thrive

Recently, researchers reviewed the incidence and management of emerging parasites and vectors associated with human and veterinary organisms.

20 Nov 2022

FDA approves first-ever type 1 diabetes delaying drug Tzield (teplizumab-mzwv)

On November 17, 2022, the US Food and Drug Administration (FDA) approved a pathbreaking new drug called Tzield. This injectable formulation contains a combination of two drugs that could push back the onset of type 1 diabetes (T1D) in adults at stage 3 and children aged eight years or more at stage 2.

20 Nov 2022

Preparing for epidemics now and in the future

The World Health Organization (WHO) recently conducted a virtual press conference on global health emergencies on November 16, 2022. Margaret Harris hosted the conference at WHO Headquarters in Geneva. In addition, a broad panel of technical experts was present online and offline for discussion.

20 Nov 2022

Dietary change could be a key to enhancing colon cancer treatment

A dietary change could be a key to enhancing colon cancer treatment, a new study from the University of Michigan Rogel Cancer Center finds.

20 Nov 2022

Researchers uncover new therapeutic vulnerability in endocrine therapy-resistant breast cancers

For patients with estrogen receptor (ER)-positive breast cancer, development of the so-called Y537S mutation signals that their disease has taken an aggressive course and may become resistant to endocrine therapy.

20 Nov 2022

New approach for delivering medication across the blood-brain barrier to treat brain tumors

Researchers have demonstrated in mice a new approach for delivering medication across the blood-brain barrier to treat tumors that cause aggressive, lethal brain cancer.

20 Nov 2022

β-cyclodextrin family found to be promising and cost-effective antiviral agents against SARS-CoV-2

Researchers identified β-cyclodextrins (β-CDs) as a safe and cost-effective drug against SARS-CoV-2 with a broad spectrum of activity.

18 Nov 2022

World Antimicrobial Awareness Week: Preventing Antimicrobial Resistance Together

In this interview, News-Medical talks to Dr Javier Yugueros-Marcos, Head of the Antimicrobial Resistance and Veterinary Products Department at the World Organisation for Animal Health, about how the world can work together to promote the sustainable and responsible use of antimicrobials.

18 Nov 2022

Efficacy News and Research

Potent hypervalent nanoparticles against HIV, Lassa and SARS-CoV-2 variants

Johns Hopkins experts receive PCORI funding to optimize antibiotic therapy for gram-negative bloodstream infections

Comprehensive analysis outlines the potential toxicities of antibody drug conjugates

New method for isolating Omicron subvariant and evaluating resistance to therapeutic and vaccine-elicited antibodies

WHO‒recommended alcohol-based hand rub formulations show efficacy against Monkeypox virus

CAR T-cell therapy in colorectal cancer

Rutgers scientists develop new approach to effectively shut down viral infections

In our rapidly changing world, parasites and vectors thrive

FDA approves first-ever type 1 diabetes delaying drug Tzield (teplizumab-mzwv)

Preparing for epidemics now and in the future

Dietary change could be a key to enhancing colon cancer treatment

Researchers uncover new therapeutic vulnerability in endocrine therapy-resistant breast cancers

New approach for delivering medication across the blood-brain barrier to treat brain tumors

β-cyclodextrin family found to be promising and cost-effective antiviral agents against SARS-CoV-2

World Antimicrobial Awareness Week: Preventing Antimicrobial Resistance Together

The antimicrobial activity of tee tree oil nanoliposomes against Escherichia coli

Pt(IV)-conjugated drug-delivery system shows efficacy in glioblastoma therapy

Study identifies risk factors and symptom clusters associated with long-COVID

Bispecific antibodies neutralize Sarbecoviruses with increased breadth and potency

What is the immune protection generated by SARS-CoV-2 Delta and Omicron BA.1 and BA.2 against Omicron BA.4 and BA.5?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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