Genetic News and Research

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Controllable chiral switching in double-helical foldamers for advanced molecular systems

The deoxyribonucleic acid or DNA, the molecular system that carries the genetic information of living organisms, can transcribe and amplify information using its two helical strands.

9 Aug 2024

Machine learning revolutionizes gene delivery

Gene therapy could potentially cure genetic diseases but it remains a challenge to package and deliver new genes to specific cells safely and effectively. Existing methods of engineering one of the most commonly used gene-delivery vehicles, adeno-associated viruses (AAV), are often slow and inefficient.

9 Aug 2024

Columbia study reveals bacteria create free-floating genes, challenging genetic code norms

Since the genetic code was first deciphered in the 1960s, our genes seemed like an open book. By reading and decoding our chromosomes as linear strings of letters, like sentences in a novel, we can identify the genes in our genome and learn why changes in a gene's code affect health.

9 Aug 2024

NIH awards $3.5M grant to study link between traumatic brain injury and Alzheimer's

A traumatic brain injury, or TBI, is caused by a contusion to the head that may result in injury to the brain.

8 Aug 2024

Increased skin-to-skin time linked to better neurodevelopment

Skin-to-skin cuddling with a parent has lasting cognitive benefits for premature babies, according to a new Stanford Medicine study. Preemies who received more skin-to-skin contact, also known as kangaroo care, while hospitalized as newborns were less likely to be developmentally delayed at 1 year of age, the study found.

8 Aug 2024

Amyloid immunotherapy for early Alzheimer's: Promising but fraught with challenges

Researchers highlighted the complexities of using amyloid immunotherapy for early Alzheimer's disease, discussing its clinical benefits, challenges, and broader health implications. Despite some positive results, concerns over adverse effects, trial biases, and cost hinder widespread adoption.

7 Aug 2024

New treatment boosts pluripotent stem cell production in mice

Researchers at the Centre for Genomic Regulation (CRG) have discovered a treatment which accelerates the production and quality of pluripotent stem cells in mice.

7 Aug 2024

Study reveals key brain cells help resist food temptations in favor of exercise

Hypocretin/orexin neurons (HONs) are crucial for resisting temptation and choosing exercise over highly palatable foods. This finding highlights potential targets for promoting physical activity and combating obesity.

7 Aug 2024

Social genomics: How friends' genes impact a person's mental health

Mom always said, "Choose your friends wisely." Now a study led by a Rutgers Health professor shows she was onto something: Their traits can rub off on you – especially ones that are in their genes.

7 Aug 2024

Decoding glioblastoma: New insights into molecular subtypes and mesenchymal transition mechanisms

Glioblastoma multiforme (GBM) stands as a formidable adversary in oncology, characterized by its molecular complexity and relentless progression.

7 Aug 2024

Healthy diet and exercise can mitigate genetic risk for type 2 diabetes, study finds

A new study from the University of Eastern Finland is the first in the world to show that a healthy diet and regular exercise reduce the risk of type 2 diabetes even in individuals with a high genetic risk.

7 Aug 2024

From discovery to approval: Vorasidenib approved by FDA for treatment of IDH-mutant gliomas

A new drug for treatment of a type of brain cancer, called IDH-mutant low-grade glioma, was approved Aug. 6 by the U.S. Food and Drug Administration (FDA).

7 Aug 2024

METRNL protein identified as key player in cancer progression

A protein called Meteorin-like (METRNL) in the tumor microenvironment saps energy from T cells, thereby severely limiting their ability to fight cancer, according to new research directed by investigators at the Johns Hopkins University School of Medicine and the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. Finding ways to block the effects of METRNL signaling on tumor-infiltrating T cells may allow these immune cells to regain the energy necessary to eliminate tumors.

7 Aug 2024

Study advances understanding of complex neurological disorder

To effectively treat a disease or disorder, doctors must first know the root cause. Such is the case for developmental and epileptic encephalopathies (DEEs), whose root causes can be hugely complex and heterogeneous. Scientists at St. Jude Children's Research Hospital demonstrated the value of DNA methylation patterns for identifying the root cause of DEEs, showing specific gene methylation and genome-wide methylation "episignatures" can help identify the genes that cause DEE. The findings were published today in Nature Communications.

7 Aug 2024

Study uncovers how TREM2 R47H mutation affects Alzheimer's plaques

Researchers led by the University of California, Irvine have discovered how the TREM2 R47H genetic mutation causes certain brain areas to develop abnormal protein clumps, called beta-amyloid plaques, associated with late-onset Alzheimer's disease.

6 Aug 2024

Study reveals distinct genetic risk factors for influenza and COVID-19

A recent study in Nature Genetics reports that genetic risk factors for influenza and COVID-19 are distinct, highlighting their unique genetic architectures.

6 Aug 2024

Brain chemical orexin plays key role in choosing exercise over treats

Should I go and exercise, or would I rather go to the café and enjoy a delectable strawberry milkshake? Until now, what exactly happens in our brain when we make this decision has been a mystery to science, but researchers at ETH Zurich have found the solution.

6 Aug 2024

Genetic News and Research

Controllable chiral switching in double-helical foldamers for advanced molecular systems

Machine learning revolutionizes gene delivery

Columbia study reveals bacteria create free-floating genes, challenging genetic code norms

NIH awards $3.5M grant to study link between traumatic brain injury and Alzheimer's

Increased skin-to-skin time linked to better neurodevelopment

Amyloid immunotherapy for early Alzheimer's: Promising but fraught with challenges

New treatment boosts pluripotent stem cell production in mice

Study reveals key brain cells help resist food temptations in favor of exercise

Social genomics: How friends' genes impact a person's mental health

Decoding glioblastoma: New insights into molecular subtypes and mesenchymal transition mechanisms

Healthy diet and exercise can mitigate genetic risk for type 2 diabetes, study finds

From discovery to approval: Vorasidenib approved by FDA for treatment of IDH-mutant gliomas

METRNL protein identified as key player in cancer progression

Study advances understanding of complex neurological disorder

Study uncovers how TREM2 R47H mutation affects Alzheimer's plaques

Study reveals distinct genetic risk factors for influenza and COVID-19

Brain chemical orexin plays key role in choosing exercise over treats

Dopamine treatment can reduce Alzheimer's plaques and improve memory

Advancing risk stratification for DSP cardiomyopathy with postmortem genetic testing

Elevated metal levels in plasma and urine associated with greater ALS risk and shorter survival

Sequencing & Genomics: Elevating Science and Healthcare eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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