Preclinical News and Research

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ISCT selects London as host city for 2017 landmark conference to celebrate silver jubilee year

The International Society for Cellular Therapy, the global society of clinicians, researchers, regulatory specialists, technologists, and industry partners dedicated to the translation of cellular therapy into safe and effective therapies to improve patients’ lives, today announces they have awarded London as the host city for the landmark ISCT 2017 Annual Meeting to be held on May 3-6, at ExCeL London Exhibition and Convention Centre, UK to celebrate the Society’s 25th silver jubilee year. More than 1,600 international delegates are expected to attend.

10 Aug 2016

Gasotransmitters in the body could potentially be used to develop new drugs

Gases once thought of only as environmental pollutants are now known to be produced by the body. They could potentially be used to develop drugs to treat diseases including heart failure and cancer.

8 Aug 2016

Scientists develop novel multifunctional platform to integrate imaging and photo-induced cancer therapy

Physicists from The University of Texas at Arlington are leading a multidisciplinary project with The University of Texas Southwestern Medical Center in Dallas and The University of Texas MD Anderson Cancer Center in Houston to develop a new multifunctional platform that can integrate imaging and photo-induced cancer therapy in a single, portable device.

5 Aug 2016

Researchers report promising vaccine strategy for immunizing against herpes viruses

Oral and genital herpes are caused by the herpes simplex virus type 1 (HSV-1) and the herpes simplex virus type 2 (HSV-2), which both cause lifelong infection. HSV-2 infection is associated with increased risk for HIV infection.

4 Aug 2016

Rice University bioengineer receives NIH grant to study use of AAV-based therapy to combat ovarian cancer

Rice University bioengineer Junghae Suh has been awarded a prestigious R01 grant by the National Institutes of Health to research the use of viral gene therapy to fight ovarian cancer.

3 Aug 2016

Naturally occurring estrogen in cow’s milk does not affect blood hormone levels, study shows

Estrogen occurs naturally in cow's milk. Recently, there has been concern that consuming milk containing elevated amounts of estrogen could affect blood levels of the hormone in humans, leading to an increased risk of some cancers.

3 Aug 2016

Lower weight late in life linked to greater risk for Alzheimer's disease

Researchers at Brigham and Women's Hospital and Massachusetts General Hospital have found an association between lower weight and more extensive deposits of the Alzheimer's-associated protein beta-amyloid in the brains of cognitively normal older individuals.

2 Aug 2016

UTA researchers find how changing estrogen levels make women more vulnerable to cocaine addiction

Researchers at The University of Texas at Arlington are studying how fluctuating estrogen levels make females increasingly sensitive to the rewarding effects of cocaine and ultimately, vulnerable to cocaine addiction.

2 Aug 2016

Preclinical data on Selecta’s novel immune tolerance platform published in Nature Nanotechnology

Selecta Biosciences, Inc., a clinical-stage biopharmaceutical company developing targeted antigen-specific immune therapies for rare and serious diseases, announced today that Nature Nanotechnology has published an article that presents preclinical results from Selecta’s research which demonstrate the broad potential applicability of Selecta’s novel immune tolerance platform.

2 Aug 2016

Scientists use animal model to gain better understanding of cocaine addiction

Scientists at Wake Forest Baptist Medical Center are one step closer to understanding what causes cocaine to be so addictive. The research findings are published in the current issue of the Journal of Neuroscience.

2 Aug 2016

USPTO grants key patent for Quark Pharmaceuticals' QPI-1007 ocular neuroprotectant

Quark Pharmaceuticals, Inc. today announced that the United States Patent and Trademark Office has granted a key patent covering the treatment of patients suffering from non-arteritic anterior ischemic optic neuropathy ("NAION") with the Company's ocular neuroprotectant QPI-1007.

30 Jul 2016

Study clarifies role of KLF12 in CRC tumor growth

Results of preclinical studies by MUSC investigators reported in the July 2016 issue of PLOS One, demonstrate for the first time that the transcription factor KLF12 promotes CRC cell growth, in part, by activating EGR1. Furthermore, data demonstrate that KLF12 and EGR1 levels synergistically correlate with poor CRC prognoses.

29 Jul 2016

Triple-combination therapy patch shrinks tumors, prevents recurrence in colon cancer mice model

Investigators at Brigham and Women's Hospital have developed a hydrogel patch that can adhere to tumors in a preclinical model of colon cancer, delivering a local, combination treatment as the elastic gel breaks down over time.

29 Jul 2016

Experts recommend several measures to reduce firearm suicide rates in the U.S.

Researchers from Columbia University Medical Center nd New York State Psychiatric Institute have found that legislation reducing access to firearms has lowered firearm suicide rates in other countries.

29 Jul 2016

Study verifies human gene therapy in MPS I animal model

Researchers are closer to finding a better way to treat children with a rare metabolic disorder called MPS I. It is caused by a deficiency of the key enzyme IDUA needed to break down complex sugars in cells.

29 Jul 2016

World's largest public-private partnership focuses on tackling antibiotic resistance

The U.S. Department of Health and Human Services, the Wellcome Trust of London, the AMR Centre of Alderley Park, Cheshire in the United Kingdom and Boston University School of Law today announced the establishment of one of the world's largest public-private partnerships focused on tackling antibiotic resistance, an emerging modern threat to public health worldwide.

29 Jul 2016

New gene therapy shows promising results for treating neurodegenerative disorders

A new gene therapy approach designed to replace the enzyme that is deficient in patients with the inherited neurodegenerative disorders Tay-Sachs and Sandhoff diseases successfully delivered the therapeutic gene to the brains of treated mice, restored enzyme function, and extended survival by about 2.5-fold.

28 Jul 2016

Study finds biological basis for gastrointestinal symptoms in people with non-celiac wheat sensitivity

A new study may explain why people who do not have celiac disease or wheat allergy nevertheless experience a variety of gastrointestinal and extra-intestinal symptoms after ingesting wheat and related cereals.

26 Jul 2016

Odor identification test may help detect early-stage Alzheimer's disease

Researchers from Columbia University Medical Center, New York State Psychiatric Institute, and NewYork-Presbyterian reported that an odor identification test may prove useful in predicting cognitive decline and detecting early-stage Alzheimer's disease.

26 Jul 2016

New research collaboration aims to advance clinical trials of Cell Pouch System in people with type 1 diabetes

A new research funding agreement between the Juvenile Diabetes Research Foundation and Sernova, a clinical-stage regenerative medicine biotech, aims to address people with severe type 1 diabetes (T1D) who are hypoglycemia unaware, a condition in which a person with diabetes does not experience the usual early warning symptoms of hypoglycemia (low blood sugar) following an insulin injection.

26 Jul 2016

Preclinical News and Research

ISCT selects London as host city for 2017 landmark conference to celebrate silver jubilee year

Gasotransmitters in the body could potentially be used to develop new drugs

Scientists develop novel multifunctional platform to integrate imaging and photo-induced cancer therapy

Researchers report promising vaccine strategy for immunizing against herpes viruses

Rice University bioengineer receives NIH grant to study use of AAV-based therapy to combat ovarian cancer

Naturally occurring estrogen in cow’s milk does not affect blood hormone levels, study shows

Lower weight late in life linked to greater risk for Alzheimer's disease

UTA researchers find how changing estrogen levels make women more vulnerable to cocaine addiction

Preclinical data on Selecta’s novel immune tolerance platform published in Nature Nanotechnology

Scientists use animal model to gain better understanding of cocaine addiction

USPTO grants key patent for Quark Pharmaceuticals' QPI-1007 ocular neuroprotectant

Study clarifies role of KLF12 in CRC tumor growth

Triple-combination therapy patch shrinks tumors, prevents recurrence in colon cancer mice model

Experts recommend several measures to reduce firearm suicide rates in the U.S.

Study verifies human gene therapy in MPS I animal model

World's largest public-private partnership focuses on tackling antibiotic resistance

New gene therapy shows promising results for treating neurodegenerative disorders

Study finds biological basis for gastrointestinal symptoms in people with non-celiac wheat sensitivity

Odor identification test may help detect early-stage Alzheimer's disease

New research collaboration aims to advance clinical trials of Cell Pouch System in people with type 1 diabetes

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