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FDA approves Onglyza (saxagliptin) for type 2 diabetes

The U.S. Food and Drug Administration has approved Onglyza (saxagliptin), a once-daily tablet to treat Type 2 diabetes in adults. The medication is intended to be used with diet and exercise to control high blood sugar levels.

2 Aug 2009

U.N. program has little effect in reducing deaths among children in Bangladesh, study finds

"The U.N. unveiled a multimillion dollar strategy a dozen years ago to save children worldwide, but a new [Lancet] study has found the program had surprisingly little effect in Bangladesh, one of the world's poorest countries," the Associated Press reports.

31 Jul 2009

Common food additive lecithin may help control blood lipids and reduce disease risk

Scientists at Washington University School of Medicine in St. Louis have identified a substance in the liver that helps process fat and glucose. That substance is a component of the common food additive lecithin, and researchers speculate it may one day be possible to use lecithin products to control blood lipids and reduce risk for diabetes, hypertension or cardiovascular disease using treatments delivered in food rather than medication.

31 Jul 2009

Dynamic, 3D pattern formation within protein-based gel

Modern regenerative medicine is on the lookout for implantable materials that can change as the surrounding tissue does, and two Stanford University researchers have made some new gel materials that do just that. Karin Straley and Professor Sarah Heilshorn have developed a method for preparing protein-based implant materials that can evolve with the changing needs of the host biological system. Not only can their new materials change in different ways at different times, they can do so at different places within the implant materials.

31 Jul 2009

Research suggests that zinc activates a key protein on T cells needed to fight infections

Everyone knows that vitamins "from A to zinc" are important for good health. Now, a new research study in the August 2009 print issue of the Journal of Leukocyte Biology suggests that zinc may be pointing the way to new therapeutic targets for fighting infections.

31 Jul 2009

Virulence of pandemic H1N1 virus analyzed

Laboratory studies at Kansas State University and the work of a K-State researcher are making headway in the effort to control the pandemic H1N1 virus.

31 Jul 2009

Research shows how resveratrol works as an effective therapy for life-threatening inflammation

Scientists from Scotland and Singapore have unraveled a mystery that has perplexed scientists since red wine was first discovered to have health benefits: how does resveratrol control inflammation?

31 Jul 2009

Malaria: Artemisinin resistance continues developing in western Cambodia

Artemisinin, the "basis of the most effective" malaria treatment recommended by the WHO, took nearly twice as long to clear malaria parasites in patients in western Cambodia than it did in patients in northwestern Thailand, according to a New England Journal of Medicine study, which shows the "drugs are losing their power against the disease in Cambodia," Bloomberg reports (Bennett, 7/30).

30 Jul 2009

HIV/AIDS research initiative launched in South Africa

South Africa's Science and Technology Minister Naledi Pandor on Tuesday announced a government-sponsored research initiative that "aims to combat HIV and AIDS through scientific and technological research, the development of new drugs, diagnostic tests and vaccines," SAPA/IOL reports (7/28).

30 Jul 2009

Colchicine approved for acute gout, Mediterranean fever

The U.S. Food and Drug Administration has approved Colcrys to treat acute flairs in patients with gout, a recurrent and painful form of arthritis, and patients with familial Mediterranean fever (FMF), an inherited inflammatory disorder. The medication's active ingredient is colchicine, a complex compound derived from the dried seeds of a plant known as the autumn crocus or meadow saffron (Colchicum autumnale).

30 Jul 2009

Americans spent $33.9 billion out-of-pocket on complementary and alternative medicine

Americans spent $33.9 billion out-of-pocket on complementary and alternative medicine (CAM) over the previous 12 months, according to a 2007 government survey.

30 Jul 2009

Higher drug doses needed to defeat tuberculosis in overweight and obese

The typical dose of a medication considered pivotal in treating tuberculosis effectively is much too low to account for modern-day physiques, UT Southwestern Medical Center researchers said.

30 Jul 2009

Immune responses to flu vaccine are diminished in lupus patients

Patients with the autoimmune disease systemic lupus erythematosus (SLE) have an increased risk of infection, due to both disturbances in their immune responses and treatment with immunosuppressive drugs.

30 Jul 2009

Latin America accounts for two-thirds of all confirmed H1N1 deaths

Health officials are growing increasingly concerned over the impact the H1N1 (swine) flu is having on populations living in Latin America, a region "which accounts for around two-thirds of the 816 confirmed deaths so far from the disease," the AFP/channelnewsasia.com reports. "The outlook is especially unsettling for the estimated 380 million people grappling with winter in South America, where the A(H1N1) virus is speedily propagating," the news service writes.

29 Jul 2009

Swine Flu - getting drugs to the market more rapidly

The pharmaceutical industry has been up in arms this year. Giants such as Pfizer, GSK and AstraZeneca are looking for deals in the downturn whilst competing against increasing generic competition as some of the best selling medicines are coming off patent. In addition to the sectors ever-changing landscape companies are under tremendous pressure from governments to combat the Swine flu pandemic that has gripped the world.

29 Jul 2009

New drug promises to reduce damage from a heart attack

Research into a new drug by Australian heart experts has found that it can dramatically reduce heart muscle damage after a heart attack.

28 Jul 2009

Mathematical modeling predicts Herceptin resistance

Cancer researchers are turning to mathematical models to help answer important clinical questions, and a new paper in Cancer Research, a journal of the American Association for Cancer Research, illustrates how the technique may answer questions about Herceptin resistance.

28 Jul 2009

Health lobbying means cash infusion for candidates, TV stations

"Health care groups working feverishly to shape -- or kill -- an industry-wide reform bill are lavishing campaign cash on the politicians at the center of the debate," The Salt Lake (Utah) Tribune reports.

28 Jul 2009

Gates Foundation donates additional $80 million to Indian HIV-prevention program, receives Indira Gandhi Prize for Peace, Disarmament and Development

The Bill & Melinda Gates Foundation will give an additional $80 million to Avahan, a foundation initiative launched in 2003 for HIV prevention programs in India, Bill Gates said on Thursday, the Seattle Times blog, "Business of Giving" reports.

28 Jul 2009

Research shows why HIV virus is so successful and so deadly

Retroviruses such as HIV that are already within cells are much more easily transmitted when they are next to uninfected cells than if they are floating free in the bloodstream.

28 Jul 2009