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Health reform questions continue to loom

Reuters reports that "President Barack Obama's drive to overhaul the U.S. healthcare system may be back on track thanks to Senate efforts to cut the price tag to $1 trillion, but a bipartisan deal on the sweeping proposal still is far from certain ... Senate Finance Committee Chairman Max Baucus was upbeat last week after announcing that panel members had found ways to bring the price tag to about $1 trillion over 10 years, down from an earlier estimate of a staggering $1.6 trillion ... Instead, the core group of negotiators -- three Democrats and four Republicans -- issued a tepid statement on Thursday merely affirming their commitment to continue negotiations."

30 Jun 2009

U.S. Vaccine Advisory Committee considers response to H1N1 spread

The CDC convened a national vaccine advisory committee Friday to discuss the best response to the spread of H1N1 (swine flu) with an estimated 6,000 new cases in the U.S. last week alone, Reuters reports.

30 Jun 2009

Newsweek, Boston Globe examine ways to combat mosquito-borne illness

Newsweek examines the genetic modification of mosquitoes in an effort to stem the spread of dengue fever and malaria. Dengue fever, which is transmitted by the Aedes Aegypti mosquito, "is spreading fast," according to the magazine, with more than 100 million people afflicted yearly. "There is no vaccine, no cure and no solution," it reports.

30 Jun 2009

News reports examine patients unable to pay health bills in Kenya's "cash starved" hospitals; "bad shape" of Uganda's facilities

The Los Angeles Times examines several stories of patients too poor to pay their hospital bills in Kenya that were held in a "makeshift patients' prison," until they escape or settle their debt. "Tragically, healthcare horror stories are common in Africa, where developing countries rarely have medical safety nets for the poor. But an increase in cases of cash-starved public hospitals and mortuaries detaining patients and even corpses over unpaid bills is spurring outrage in Kenya," writes the newspaper.

30 Jun 2009

Battle is on to keep swine flu out of hospitals and prisons

According to the latest update, #55, from the World Health Organisation (WHO), worldwide there have been 70,893 cases including 311 deaths from the influenza A H1N1 (swine flu).

29 Jun 2009

Discovery of second gene linked to familial testicular cancer

Specific variations or mutations in a particular can gene raise a man's risk of familial, or inherited, testicular germ-cell cancer, the most common form of this disease, according to new research by scientists at the National Institutes of Health.

29 Jun 2009

Breakthrough in combating adverse side-effects associated with quinine

Discovered back in the 1600s quinine was the first effective treatment in the fight against malaria - and it continues to be a commonly used treatment against this devastating disease. But the drug is associated with a long list of side effects which can range from sickness and headaches to blindness, deafness and in rare cases death - and until now no one knew why.

29 Jun 2009

White House: Shield biotech drugs from generics for only seven years

White House officials said Thursday that biotech drugs (also known as biologics) should only be protected from generics competition for seven years, Reuters reports.

29 Jun 2009

Is President Obama fighting the last war?

Bill and Hillary Clinton are off saving the world, he through his global foundation and she via the State Department. But their presence looms over the health care debate as surely as if they were running the White House. Their epic failure to pass reform in 1994 has become the defining object lesson in how to botch health care legislation--a lesson President Obama has obviously taken to heart. Push for reform right away; let Congress hash out the details; and, above all, don't threaten people's current insurance arrangements. You can sum up Obama's strategy for health reform as "WWCD": What Wouldn't the Clintons Do.

29 Jun 2009

VOA News examines malaria in southern Sudan

VOA News examines malaria in southern Sudan. In the region, malaria is "widespread" and accounts for "up to 30 percent of all diseases treated by health facilities." It is the "number one killer of children in southern Sudan," though there are "no reliable statistics on the number in southern Sudan who suffer, or die from, malaria," VOA News reports.

29 Jun 2009

Golimumab shows promise for rheumatoid arthritis

Golimumab, a new tumour necrosis factor-α (TNF-α) inhibitor reduces the signs and symptoms of rheumatoid arthritis in patients who have previously received any other TNF-α inhibitor, and might be a good option for patients who have inadequate responses to one or two other TNF-α inhibitors, finds an Article published Online first and in this week's edition of The Lancet.

28 Jun 2009

'Trojan horse' cancer therapy beats tumours resistant to chemotherapy

A new therapy to treat cancer has been developed by Australian scientists and it promises to have far fewer unpleasant side effects than conventional treatments and should also be much cheaper.

28 Jun 2009

Inhaled growth hormone safe for children deficient in this key protein

A multi-center clinical trial led by a Riley Hospital for Children endocrinologist has found that inhaled growth hormone (GH) is well tolerated by children with GH deficiency and that this easy-to-use method can, over a one-week period, safely deliver GH to the blood stream. In addition to having implications for those who need GH, this first pediatric study of administering it through the lungs may also help researchers interested in using this convenient method for effectively delivering other types of medications to children.

28 Jun 2009

Expanding quantum dot utility in cancer diagnosis and treatment

Quantum dots (QDs), nanoparticles that shine with extraordinary brightness when excited by light energy, have shown promise as new tools for detecting cancer at its earliest appearance, but concerns about potential toxicities have limited their clinical development. Researchers at the University of Buffalo may have found an answer to this limitation with their development of a new way to create QDs.

28 Jun 2009

Nanofountain-probe-based high-resolution patterning and single-cell injection of functionalized nanodiamonds

A research team at Northwestern University has developed a tool that can precisely deliver tiny doses of drug-carrying nanomaterials to individual cells.

28 Jun 2009

Carbon nanotubes continue to show promise in battle against cancer

Carbon nanotubes, one of the original engineered nanomaterials, also may prove to be among the most versatile, as numerous teams of investigators continue to develop novel nanotube-based therapeutic and diagnostic tools. Over the past month, three new research papers have highlighted the potential of nanotubes as weapons against cancer.

28 Jun 2009

Nanoparticle-mediated targeting of MAPK signaling predisposes tumor to chemotherapy

An interdisciplinary team of researchers at Brigham and Women's Hospital and the Harvard-Massachusetts Institute of Technology (MIT) Division of Health Sciences and Technology has demonstrated a better way to deliver cancer drugs directly to tumors.

28 Jun 2009

Harnessing nanoparticles to track cancer cell changes

The more dots there are, the more accurate a picture you get when you connect them. Cancer researchers adopting that philosophy have developed a new imaging technology that could give scientists the ability to simultaneously measure as many as 100 or more distinct features in or on a single cell. In a disease such as cancer, that capability would provide a much better picture of what is going on in individual tumor cells.

28 Jun 2009

New protein stabilisation technique could revolutionise therapeutic drug discovery

A revolutionary new protein stabilisation technique has been developed by scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) which could lead to 30 per cent more proteins being available as potential targets for drug development - opening up exciting possibilities in drug discovery.

25 Jun 2009

Healthcare outcome boost needs better studies

Evidence suggests that outcomes in many clinical settings leave a lot to be desired, which means that research into quality improvement (QI) in clinical care has the potential to greatly improve the lot of patients. Now a study in the journal Medical Care Research and Review published by SAGE suggests that both theoretical and practical improvements in QI effectiveness studies could make these into much more powerful tools for positive change.

25 Jun 2009