Efficacy News and Research

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What are the eye complications associated with monkeypox infection?

A new study describes the association between monkeypox infection and eye complications in humans.

9 Nov 2022

Can prostaglandin E2 injection improve hair growth?

A new study demonstrated that prostaglandin E2 (PGE2) stimulates hair follicle growth.

9 Nov 2022

The effect of vaccination-induced immunity on viral loads of SARS-CoV-2 Omicron variant

Researchers analyzed nationwide vaccination data and cycle threshold value data from four laboratories in Israel that conduct SARS-CoV-2 qRT-PCR tests to determine the effect of vaccination-induced immunity on the viral loads of the SARS-CoV-2 Omicron variant.

9 Nov 2022

Researchers identify 55 broadly reactive monoclonal antibodies to betacoronaviruses

In a recent study published in the journal Cell Host & Microbe, researchers pursued novel approaches that could help find monoclonal antibodies (mAbs) broadly targeting coronaviruses (CoVs), especially genera beta CoVs.

8 Nov 2022

Skipping methotrexate for one week after flu vaccine provides the same seroprotection as a two-week hold in RA patients

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, showed that discontinuing methotrexate for one week after seasonal influenza vaccination provided the same seroprotection as a two-week discontinuation period in patients with rheumatoid arthritis.

8 Nov 2022

Hybrid immunity from vaccination and Omicron BA.1 or BA.5 breakthrough infections exhibits cross-reactive efficacy against BA.2.75

Researchers recently measured the neutralizing antibody titers against the wild-type strain of SARS-CoV-2 and the SARS-CoV-2 Omicron subvariants in healthcare workers fully vaccinated with three doses of the Comirnaty vaccine who experienced breakthrough Omicron infections.

8 Nov 2022

Study: Fenofibrate not a useful strategy for decreasing COVID-19 severity

After showing promise in early laboratory research, the cholesterol-lowering drug fenofibrate had no significant effect on COVID-19 outcomes in a multicenter international randomized clinical trial led by Penn Medicine scientists.

8 Nov 2022

Novel gene editing therapy reduces circulating TTR protein levels in patients with ATTR amyloid cardiomyopathy

A single IV infusion of NTLA-2001, a novel CRISPR/Cas9-based gene editing therapy, significantly reduced circulating transthyretin (TTR) protein levels in patients with ATTR amyloid cardiomyopathy, a progressive and fatal cause of heart failure, according to late-breaking research presented today at the American Heart Association’s Scientific Sessions 2022.

7 Nov 2022

Modeling predicts a declining trend in monkeypox cases globally and on a country-specific scale

In a recent study posted to the medRxiv* server, researchers at Georgia State University, USA, generated short-term forecasts of new monkeypox cases using an ensemble and subepidemic model.

7 Nov 2022

Rosuvastatin vastly superior to six common heart health supplements

Six widely used dietary supplements often advertised to promote heart health are actually ineffective at lowering cholesterol levels.

7 Nov 2022

Study shows consistent efficacy of Paxlovid regardless of age, number of vaccinations, comorbidities

In a recent study posted to the medRxiv* preprint server, researchers in Canada evaluated nirmatrelvir and ritonavir (Paxlovid) effectiveness against severe coronavirus disease 2019 (COVID-19) during the dominance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) and Omicron sub-VOCs in Canada.

7 Nov 2022

High-intensity treatment strategy for heart failure reduces the risk of death or hospital readmission

Ramping up medication doses quickly after being hospitalized for acute heart failure resulted in a lower risk of dying or being readmitted for heart failure within the first six months after discharge, compared to usual care, according to a featured science research presentation today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Combining chemotherapy with an inflammation inhibitor can prevent breast cancer metastasis

A new treatment developed at Tel Aviv University may significantly enhance the efficacy of chemotherapy in breast cancer patients, reducing the risk for lung metastasis following chemo from 52% to only 6%.

7 Nov 2022

Paxlovid antiviral therapy reduces risk of long COVID

In a recent study posted to the medRxiv* server, researchers in Saint Louis, Missouri, examined whether nirmatrelvir treatment reduced the risk of long COVID, the disease encompassing the post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [PASC].

7 Nov 2022

Multinational consensus to end COVID-19 pandemic

A new study recommended specific actions to end the coronavirus disease 2019 (COVID-19) pandemic.

7 Nov 2022

Post-‘Roe,’ contraceptive failures carry bigger stakes

Birth control options have improved over the decades. Oral contraceptives are now safer, with fewer side effects. Intrauterine devices can prevent pregnancy 99.6% of the time. But no prescription drug or medical device works flawlessly, and people's use of contraception is inexact.

7 Nov 2022

Beyond vaccines: emerging technologies capable of unlocking the promise of biologically targeted mRNA therapeutics

Researchers reviewed technology advancements that will unlock the promise of biologically targeted messenger ribonucleic acid (mRNA) therapeutics beyond vaccines.

7 Nov 2022

Moderna's COVID-19 vaccine safe and effective in children 6 months to 5 years of age

Moderna's COVID-19 vaccine is safe and effective in children 6 months to 5 years of age, a clinical trial co-led by Vanderbilt University Medical Center vaccine expert C. Buddy Creech, MD, MPH, has found.

4 Nov 2022

UAB researchers report lack of predictability for fecal microbial transplants without prior antibiotic therapy

A fecal microbial transplant - giving a recipient fecal matter from a donor to change the recipient's gut microbial community in the colon - has been a successful last resort therapy for people with recurrent Clostridium difficile infection after multiple rounds of suppressive antibiotics have eliminated the recipient microbial community.

4 Nov 2022

Researchers identify therapies for multiple myeloma patients whose cancer relapses after CAR-T

Mount Sinai and Memorial Sloan Kettering Cancer Center (MSK) researchers have identified therapies that can help patients with the blood cancer multiple myeloma who try an immunotherapy known as CAR-T only to find their cancer coming back afterwards.

4 Nov 2022

Efficacy News and Research

What are the eye complications associated with monkeypox infection?

Can prostaglandin E2 injection improve hair growth?

The effect of vaccination-induced immunity on viral loads of SARS-CoV-2 Omicron variant

Researchers identify 55 broadly reactive monoclonal antibodies to betacoronaviruses

Skipping methotrexate for one week after flu vaccine provides the same seroprotection as a two-week hold in RA patients

Hybrid immunity from vaccination and Omicron BA.1 or BA.5 breakthrough infections exhibits cross-reactive efficacy against BA.2.75

Study: Fenofibrate not a useful strategy for decreasing COVID-19 severity

Novel gene editing therapy reduces circulating TTR protein levels in patients with ATTR amyloid cardiomyopathy

Modeling predicts a declining trend in monkeypox cases globally and on a country-specific scale

Rosuvastatin vastly superior to six common heart health supplements

Study shows consistent efficacy of Paxlovid regardless of age, number of vaccinations, comorbidities

High-intensity treatment strategy for heart failure reduces the risk of death or hospital readmission

Combining chemotherapy with an inflammation inhibitor can prevent breast cancer metastasis

Paxlovid antiviral therapy reduces risk of long COVID

Multinational consensus to end COVID-19 pandemic

Post-‘Roe,’ contraceptive failures carry bigger stakes

Beyond vaccines: emerging technologies capable of unlocking the promise of biologically targeted mRNA therapeutics

Moderna's COVID-19 vaccine safe and effective in children 6 months to 5 years of age

UAB researchers report lack of predictability for fecal microbial transplants without prior antibiotic therapy

Researchers identify therapies for multiple myeloma patients whose cancer relapses after CAR-T

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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