Genes News and Research

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Illuminating how children inherit parents’ stressful experiences

Most of us learned in high school that people get half their genes from their father and half from their mother. That's true, but it turns out the way parents contribute to their offspring's genetics is more complicated—and more intriguing.

27 Jun 2023

Measurable upticks in gut bacteria blooms tied to lupus flare-ups

Recurrent bouts of systemic lupus erythematosus, marked by the body's immune system attack of its own tissues, closely tracked with measurable upticks in growth in the gut of a certain species of bacteria.

27 Jun 2023

Are a high-refined carbohydrate diet and the alterations resulting from its intake linked to small intestine changes?

Researchers investigated whether a high-refined carbohydrate diet and associated metabolic alterations could cause small intestinal dysregulation.

27 Jun 2023

Novel computational tool helps analyze complex genetic regions

GeneDx (Nasdaq: WGS), a leader in delivering improved health outcomes through genomic and clinical insights, today published a paper in Nature Methods, titled "Multiscale analysis of pangenomes enables improved representation of genomic diversity for repetitive and clinically relevant genes," in which researchers developed a new computational tool, the PanGenome Research-Tool Kit (PGR-TK), for scalable analysis of clinically relevant genes that were previously too complex to analyze.

27 Jun 2023

Novel biomaterials approach reveals how mechanical forces shape T cell fate

The successful campaign of adoptive T cell therapies, a type of immunotherapy in which immune T cells are collected from a patient, enhanced outside of the body, and reinfused back into the same patient, especially against blood cancers is well under way.

26 Jun 2023

New kidney cancer model highlights molecular targets and genomic events that drive metastasis

Researchers at The University of Texas MD Anderson Cancer have engineered a new model of aggressive renal cell carcinoma (RCC), highlighting molecular targets and genomic events that trigger chromosomal instability and drive metastatic progression.

26 Jun 2023

New computational technique shows promise for identifying different subtypes of Alzheimer's disease

A new computational technique that combines genomic and tau PET imaging data promises a more personalized approach for subtyping Alzheimer's disease.

26 Jun 2023

Researchers pinpoint a key feature that leads to aggressive spread of colon cancer

In a significant development in the fight against fatal cancers, University of Otago researchers have pinpointed a key feature that leads to the aggressive spread of colon cancer.

26 Jun 2023

University Hospital Bonn and DZNE receive prestigious "Ataxia Center of Excellence" award

The Ataxia Center at the University Hospital Bonn (UKB) and DZNE have been awarded the title "Ataxia Center of Excellence" by the US National Ataxia Foundation (NAF) for their patient care and research – as the only organization in Europe.

26 Jun 2023

New study warns of dangers of gene editing in human embryos

Scientists have discovered that the cells of early human embryos are often unable to repair damage to their DNA.

26 Jun 2023

High BMI linked to increased risk of 5 rheumatic diseases

A new study by Uppsala University shows that a higher body mass index (BMI) increases the risk of five different rheumatic diseases: rheumatism, osteoarthritis, gout, psoriatic arthritis and inflammatory spondylitis. The researchers also noted that BMI was a stronger risk factor for women compared to men in terms of gout and psoriatic arthritis. The study will be presented in the journal Arthritis & Rheumatology.

26 Jun 2023

Innovative nanofluidic device detects single proteins at their naturally high concentrations

In the evolving world of precision medicine, the need for methods that can measure biomolecules with supreme accuracy and specificity is paramount. Recognizing this, Associate Professor Yan Xu of the Graduate School of Engineering at Osaka Metropolitan University and his international research team have made a great stride in this direction. They have developed an innovative nanofluidic device capable of capturing single proteins stochastically and detecting them digitally at their naturally high concentrations. This breakthrough could potentially lay the foundation for the future of personalized disease prevention and treatment.

26 Jun 2023

Space travel weakens immune system by altering gene expression in white blood cells

Evidence is mounting that astronauts are more susceptible to infections while in space. For example, astronauts on board the International Space Station (ISS) commonly suffer from skin rashes, as well as respiratory and non-respiratory diseases.

24 Jun 2023

Adopting a 30th birthday genetic profile test could save lives and NHS costs

A new study published in the US medical journal ‘The Annals of Internal Medicine’ makes a very strong case for universal genetic testing at the age of 30.

24 Jun 2023

IgA nephropathy: The disease that lies outside the kidney

The cause of a common kidney disease likely lies outside the kidney, according to a new study led by Columbia University researchers.

23 Jun 2023

Single-cell profiling reveals immune cell marker and regulator of anti-tumor immunity

B cells are thought to play a critical role in innate and adaptive immunity, but their exact role in anti-tumor immunity remains unknown.

23 Jun 2023

New drug could slow down antibiotic resistance

A team of researchers at Baylor College of Medicine is gaining ground in their search for solutions to the global problem of bacterial antibiotic resistance, which was responsible for nearly 1.3 million deaths in 2019.

23 Jun 2023

3D models of ovarian cancer reveal how cell’s location can affect tumor biology

Using 3-D models of ovarian cancer tumors, scientists found differences in gene activity based on where a cell is in a tumor, demonstrating how a cell's location and environment in a cancerous tumor can strongly influence which genes are active and the cell's role in the cancer's biology.

23 Jun 2023

Pangolin study uncovers novel strains of coronaviruses and raises concerns about origin

Researchers identify novel HKU4-related coronavirus in a pangolin single-cell sequencing dataset.

22 Jun 2023

Alzheimer's disease may begin during embryogenesis, stem cell study suggests

Alzheimer's disease (AD) mainly affects the older population. Recent research found early disease signs in cell culture models of early human brain development, raising the possibility that the disease has its origins much earlier in life, possibly during embryogenesis – the formation and development of an embryo.

22 Jun 2023

Genes News and Research

Illuminating how children inherit parents’ stressful experiences

Measurable upticks in gut bacteria blooms tied to lupus flare-ups

Are a high-refined carbohydrate diet and the alterations resulting from its intake linked to small intestine changes?

Novel computational tool helps analyze complex genetic regions

Novel biomaterials approach reveals how mechanical forces shape T cell fate

New kidney cancer model highlights molecular targets and genomic events that drive metastasis

New computational technique shows promise for identifying different subtypes of Alzheimer's disease

Researchers pinpoint a key feature that leads to aggressive spread of colon cancer

University Hospital Bonn and DZNE receive prestigious "Ataxia Center of Excellence" award

New study warns of dangers of gene editing in human embryos

High BMI linked to increased risk of 5 rheumatic diseases

Innovative nanofluidic device detects single proteins at their naturally high concentrations

Space travel weakens immune system by altering gene expression in white blood cells

Adopting a 30th birthday genetic profile test could save lives and NHS costs

IgA nephropathy: The disease that lies outside the kidney

Single-cell profiling reveals immune cell marker and regulator of anti-tumor immunity

New drug could slow down antibiotic resistance

3D models of ovarian cancer reveal how cell’s location can affect tumor biology

Pangolin study uncovers novel strains of coronaviruses and raises concerns about origin

Alzheimer's disease may begin during embryogenesis, stem cell study suggests

eBook: Using iPSCs models for human disease research and drug discovery eBook

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