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New tool accelerates drug discovery

The development of molecules to study and treat disease is becoming increasingly burdened by the time and specificity required to analyze the vast amounts of data generated by synthesizing large collections of new molecules.

12 Dec 2024

Harnessing exosomes to deliver therapeutic proteins

Researchers at The Ottawa Hospital and the University of Ottawa have discovered an 18-digit code that allows proteins to attach themselves to exosomes - tiny pinched-off pieces of cells that travel around the body and deliver biochemical signals.

11 Dec 2024

Modified chemotherapy regimen for Hodgkin lymphoma reduces long-term side effects

A simple change to the chemotherapy regimen for people with Hodgkin lymphoma could reduce the long-term health impacts that can result from treatment, according to researchers in Cambridge.

11 Dec 2024

Personalized blood test setpoints offer early disease detection

A complete blood count (CBC) screening is a routine exam requested by most physicians for healthy adults.

11 Dec 2024

Exosomes: A double-edged sword in hepatocellular carcinoma

The TIME is a dynamic network composed of cancer cells, immune cells, and stromal components. During the early stages of tumorigenesis, the TIME attempts to eliminate abnormal cells through immune surveillance.

11 Dec 2024

Understanding how angiogenesis contributes to drug resistance in breast cancer

Breast cancer, the most common cancer among women, is notorious for its ability to develop resistance to a wide range of treatments, including surgery, chemotherapy, targeted therapies, and immunotherapy.

11 Dec 2024

Study highlights global surge in early-onset colorectal cancer

A new study led by American Cancer Society (ACS) researchers shows that early-onset colorectal cancer (CRC) incidence rates are rising in 27 of 50 countries/territories worldwide, 20 of which have either exclusive or faster increases for early-onset disease.

11 Dec 2024

Risk-reducing surgeries provide benefits for young BRCA-mutation carriers

Patients with germline BRCA mutations who were diagnosed with breast cancer at or before age 40 and who underwent a bilateral risk-reducing mastectomy (RRM) and/or a risk-reducing salpingo-oophorectomy (RRSO) had lower rates of recurrence, secondary breast and/or ovarian malignancies, and death than those who did not undergo these surgeries, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

11 Dec 2024

Weight gain after 35 linked to increased breast cancer risk

The body mass index (BMI) has long been used to measure body fat, but its influence on breast cancer risk is more complex than previously thought.

11 Dec 2024

Cleveland Clinic study reveals kidney microbiome's role in renal health

Cleveland Clinic researchers have found definitive proof of a kidney microbiome that influences renal health and kidney stone formation, demonstrating that the urinary tract is not sterile and low levels of bacteria are normal.

11 Dec 2024

TCR sequencing sheds light on tumor immune interactions in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) stands as the dominant form of liver cancer, ranking as the fourth leading cause of cancer-related deaths globally.

11 Dec 2024

New research explores hidden health risks of hereditary hemochromatosis

A study links undetected diabetes in hemochromatosis patients to increased mortality, highlighting the need for early detection and revised clinical guidelines.

11 Dec 2024

Study highlights disparities in stroke costs across healthcare services in Latin America

This study assesses acute ischemic stroke costs in Latin America, revealing treatment variations and economic challenges that impact healthcare accessibility.

11 Dec 2024

Quality breakfast reduces the risk of cardiovascular disease

Having a quality breakfast that provides the right amount of energy to face the day, around a quarter of daily intake, reduces the risk of cardiovascular disease.

11 Dec 2024

Former Montana health staffer rebukes oversight rules as a hospital ‘wish list’

A former Montana health department staffer who described himself as the lead author of legislation to scrutinize nonprofit hospitals’ charitable acts said new rules implementing the bill amounted to a hospital "wish list" and that the state needs to go back to the drawing board.

11 Dec 2024