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Fecal microbiota transplants can boost the effectiveness of immunotherapy in gastrointestinal cancers

Findings from a small, proof-of-concept clinical trial have suggested that fecal microbiota transplants (FMTs) can boost the effectiveness of immunotherapy in a range of gastrointestinal cancers.

25 Jul 2024

Novel antisense therapy targets α-synuclein pathologies in neurodegenerative diseases

TMDU researchers demonstrate proof of concept of antisense nucleic acid therapy to prevent the spread of α-synuclein pathologies in synucleinopathies.

25 Jul 2024

FAU researcher wins $701,000 grant to revolutionize cancer treatment

While chemotherapy has advanced in personalization, personalized radiation therapy for cancer remains underdeveloped.

25 Jul 2024

Texas Heart Institute and BiVACOR achieve milestone with total artificial heart implantation

The Texas Heart Institute (THI) and BiVACOR, a clinical-stage medical device company, announced today the successful first-in-human implantation of the BiVACOR Total Artificial Heart (TAH) as part of the U.S. Food and Drug Administration (FDA) Early Feasibility Study (EFS) on July 9, 2024.

25 Jul 2024

Study highlights infection as major post-CAR-T therapy challenge

In patients with diffuse large B-cell non-Hodgkin lymphoma (DLBCL), the two hallmark post-chimeric antigen receptor (CAR)-T therapy toxicities are extremely rare after two weeks, supporting a shorter, more flexible toxicity monitoring period, according to a study published in Blood Advances.

25 Jul 2024

Cord blood banking industry faces scrutiny over unproven claims and high costs

Some private UK biobanks may be misleading expectant parents about the value of storing umbilical cord blood to treat life-threatening diseases that may arise in their child in the future, reveals an investigation by The BMJ, published today.

25 Jul 2024

Cognitive decline persists in older adults long after severe COVID-19 recovery

Older adults recovering from COVID-19 experience varying degrees of cognitive decline over 2.5 years, with severe cases showing the most significant impact. Early cognitive care and monitoring are crucial for improving outcomes.

24 Jul 2024

Retinoblastoma therapy evolves with higher success rates and lower complications

The evolution of retinoblastoma treatment over the past 15 years has resulted in a higher likelihood of vision preservation without compromising survival, according to research released today at the Society of NeuroInterventional Surgery's (SNIS) 21st Annual Meeting.

24 Jul 2024

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Researchers discovered that oligodendrocytes, not just neurons, produce amyloid β in Alzheimer's disease, and suppressing their activity improves disease pathology. This finding suggests new therapeutic targets for Alzheimer's treatment.

24 Jul 2024

Breakthrough gene therapy restores dystrophin protein in Duchenne muscular dystrophy

Indiana University School of Medicine researchers have made a significant breakthrough in developing a new gene therapy approach that restores full-length dystrophin protein, which could lead to new treatments for people with Duchenne muscular dystrophy (DMD).

24 Jul 2024

Proof-of-concept animal studies demonstrate a step forward in the fight against HIV

Researchers in George Mason University's Center for Infectious Disease Research (CIDR) and Tulane National Primate Research Center conducted a breakthrough proof-of-concept study in Nature's Gene Therapy that found an HIV-like virus particle that could cease the need for lifelong medications.

24 Jul 2024

Simple blood test may predict CAR-T therapy success in multiple myeloma

A simple blood test that measures the number of lymphocytes, a type of white blood cell in the body, may predict whether people who have relapsed multiple myeloma are going to respond well to CAR-T immunotherapy, according to new research from Weill Cornell Medicine, NewYork-Presbyterian, Columbia University and Icahn School of Medicine at Mount Sinai.

24 Jul 2024

AI improves breast cancer staging by analyzing chromatin images

Researchers at the Paul Scherrer Institute PSI and the Massachusetts Institute of Technology MIT are using artificial intelligence to improve the categorization of breast cancer.

24 Jul 2024

CHEST releases new clinical guideline for managing central airway obstruction

The American College of Chest Physicians (CHEST) recently released a new clinical guideline on central airway obstruction (CAO).

24 Jul 2024

Community pharmacists help close gaps in stroke prevention for Afib patients

Atrial fibrillation (Afib) is the most common heart rhythm disorder encountered in clinical practice according to Dr. Roopinder Sandhu, MD, MPH, and the leading cause of stroke in older individuals.

24 Jul 2024

Kaempferol's promise in fighting triple-negative breast cancer

Review highlights kaempferol's potential in treating triple-negative breast cancer through various anticancer mechanisms and improving chemotherapeutic efficacy.

24 Jul 2024

$ActiveHip+ enhances recovery for elderly hip fracture patients$

ActiveHip+ enhances recovery for elderly hip fracture patients

This digital solution was developed as part of a European project led by the University of Granada (UGR) and the Andalusian Health Service (SAS).

24 Jul 2024

Broken String Biosciences appoints Steve Becker as Chief Commercial Officer

Broken String Biosciences (“Broken String”), a genomics company driving development of the next generation of more precise, safe, and effective cell and gene therapies, today announced it has appointed Steve Becker as Chief Commercial Officer.

24 Jul 2024

Enterprise Therapeutics doses first person with cystic fibrosis in Phase 2 trial for novel therapy ETD001

Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of those suffering from respiratory disease, today announced dosing of the first person with cystic fibrosis (pwCF) in its Phase 2a trial of ETD001.

24 Jul 2024

Associations between gut microbes and Alzheimer’s disease

Researchers reviewed existing data on the role of the gut microbiome in Alzheimer’s disease (AD) pathogenesis.

24 Jul 2024

Therapy News and Research

Fecal microbiota transplants can boost the effectiveness of immunotherapy in gastrointestinal cancers

Novel antisense therapy targets α-synuclein pathologies in neurodegenerative diseases

FAU researcher wins $701,000 grant to revolutionize cancer treatment

Texas Heart Institute and BiVACOR achieve milestone with total artificial heart implantation

Study highlights infection as major post-CAR-T therapy challenge

Cord blood banking industry faces scrutiny over unproven claims and high costs

Cognitive decline persists in older adults long after severe COVID-19 recovery

Retinoblastoma therapy evolves with higher success rates and lower complications

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Breakthrough gene therapy restores dystrophin protein in Duchenne muscular dystrophy

Proof-of-concept animal studies demonstrate a step forward in the fight against HIV

Simple blood test may predict CAR-T therapy success in multiple myeloma

AI improves breast cancer staging by analyzing chromatin images

CHEST releases new clinical guideline for managing central airway obstruction

Community pharmacists help close gaps in stroke prevention for Afib patients

Kaempferol's promise in fighting triple-negative breast cancer

ActiveHip+ enhances recovery for elderly hip fracture patients

Broken String Biosciences appoints Steve Becker as Chief Commercial Officer

Enterprise Therapeutics doses first person with cystic fibrosis in Phase 2 trial for novel therapy ETD001

Associations between gut microbes and Alzheimer’s disease

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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