Transplant News and Research

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Novo Nordisk, BRI collaborate to speed-up translational research of autoimmune diseases

Benaroya Research Institute at Virginia Mason (BRI), a non-profit biomedical research institute in Seattle, Wash., and Novo Nordisk, a global health care company headquartered in Denmark, today announced a three-year collaborative agreement to potentially speed-up translational research of the diagnosis and treatment of rheumatoid arthritis, inflammatory bowel disease and lupus.

29 Jun 2012

UCLA Heart Transplant Program performs 2,000th heart transplant surgery

The UCLA Heart Transplant Program performed its 2,000th heart transplant surgery earlier this month, becoming the first program in the western United States and only the second in the world to achieve this remarkable milestone.

28 Jun 2012

LUMC oncologist presents survival data for brentuximab vedotin at 17th EHA Congress

A new cancer drug with remarkably few side effects is dramatically improving survival in Hodgkin lymphoma patients who fail other treatments and are nearly out of options.

28 Jun 2012

TB research finds body’s own response helps TB bacteria survive

Inhibiting a key immune response in mice during initial multi-drug treatment for tuberculosis could — paradoxically — shorten treatment time for the highly contagious lung infection according to new research from Johns Hopkins Children’s Center and the Center for TB Research. Shorter duration of drug therapy is key, researchers say, to increase treatment compliance for the growing global health threat posed by the disease.

28 Jun 2012

Scientists transplant stem cells from patients with limb-girdle muscular dystrophy into mice

Stem cells from patients with a rare form of muscular dystrophy have been successfully transplanted into mice affected by the same form of dystrophy, according to a new study published today in Science Translational Medicine.

28 Jun 2012

Pediatric Hodgkin lymphoma can be treated without radiation and intensive chemotherapy

A multicenter trial showed that nearly half of young patients with early-stage Hodgkin lymphoma can be cured without undergoing either irradiation or intensive chemotherapy that would leave them at risk for second cancers, infertility, heart and other problems later.

28 Jun 2012

Scientists reverse diabetes in mice using stem cells

University of British Columbia scientists, in collaboration with an industry partner, have successfully reversed diabetes in mice using stem cells, paving the way for a breakthrough treatment for a disease that affects nearly one in four Canadians.

28 Jun 2012

Magnet guides iron-loaded cells to specific damaged sites in the heart

Optimal stem cell therapy delivery to damaged areas of the heart after myocardial infarction has been hampered by inefficient homing of cells to the damaged site. However, using rat models, researchers in France have used a magnet to guide cells loaded with iron oxide nanoparticles to key sites, enhancing the myocardial retention of intravascularly delivered endothelial progenitor cells.

27 Jun 2012

SIR/TAC combination more effective in preventing GVHD after allogeneic blood cell transplantation

Researchers at Moffitt Cancer Center have conducted a clinical trial aimed at preventing graft vs. host disease (GVHD) in patients who have received hematopoietic (blood) cell transplants (HCT). The study, comparing the drug tacrolimus (TAC) in combination with either methotrexate (MTX ) or sirolimus (SIR), found that the sirolimus/tacrolimus (SIR/TAC) combination was more effective in preventing grades II-IV acute GVHD and moderate-severe chronic GVHD after allogeneic blood cell transplantation.

27 Jun 2012

ESCs and iPSCs demonstrate similar survival and neural differentiation capabilities

Researchers in Japan who evaluated the risks and efficacy of transplanting two varieties of stem cells into mouse cochlea have concluded that both adult-derived induced pluripotent stem (iPS) cells and mouse embryonic stem (ES) cells demonstrate similar survival and neural differentiation capabilities.

27 Jun 2012

Poor prognosis for heart transplant patients with restenosis

Orthotopic heart transplant patients who develop in-stent restenosis after percutaneous coronary intervention have a poor long-term prognosis, research suggests.

26 Jun 2012

World-renowned pediatric cardiac surgeon performs 10,000th milestone operation

Edward L. Bove didn't know he was hitting a major milestone this spring, but the world-renowned pediatric cardiac surgeon performed his 10,000th surgery on March 27 at the University of Michigan's C.S. Mott Children's Hospital.

26 Jun 2012

New analysis finds increase in per-patient operating costs in PCMHs

The patient-centered medical home (PCMH) is a concept at the heart of many health care reform models that aim to both improve the quality of care and reduce wasteful spending. But a new analysis of federally qualified health centers finds that clinics with higher scores as medical homes also had higher per-patient operating costs.

25 Jun 2012

Deferasirox reduces elevated iron levels in patients with myelodysplastic syndrome

Researchers at Moffitt Cancer Center and colleagues at six other institutions have recently tested a treatment for patients with myelodysplastic syndrome, or MDS, a blood-related malignancy that involves the ineffective production of blood cells, leaving patients anemic and in need of frequent blood transfusions. Because the body has no natural means to reduce iron that accumulates from repeated transfusions, patients' organs can become iron overloaded, leading to heart failure, liver injury, susceptibility to infection, and other complications.

23 Jun 2012

CARHY announces comprehensive hematopoietic stem cell transplant service

Adding an impetus to the already existing image of Bangalore being a healthcare destination of India, Columbia Asia Referral Hospital, Yeshwanthpur (CARHY), announced comprehensive bone marrow transplant (stem cell transplant) service on Thursday.

23 Jun 2012

Wake Forest Baptist researchers achieve early milestone in lab-engineered kidney project

Regenerative medicine researchers at Wake Forest Baptist Medical Center have reached an early milestone in a long-term project that aims to build replacement kidneys in the lab to help solve the shortage of donor organs.

23 Jun 2012

Structured exercise programmes benefit lung transplant patients

Lung transplant patients who took part in a three-month structured exercise program when they were discharged from hospital improved their health-related quality of life and reduced their risk of cardiovascular problems.

22 Jun 2012

Parents must be considered during expansion of genetic screening programs for newborns

Parents must be considered when states decide to expand genetic screening programs for newborns, according to a new study that looked at mandatory testing panels and political pressure by advocacy groups.

22 Jun 2012

New methods to track stem cells

Researchers at the University of Liverpool have developed new methods to track stem cells and further understanding of what happens to them after they have been in the body for a significant period of time.

22 Jun 2012

Largest study to examine impact of gastric sleeve surgery on pre-transplant obese patients

Morbidly obese patients with end-stage organ failure may improve their chances for successful organ transplantation after laparoscopic sleeve gastrectomy, according to a new study presented here at the 29th Annual Meeting of the American Society for Metabolic & Bariatric Surgery (ASMBS).

21 Jun 2012

Transplant News and Research

Novo Nordisk, BRI collaborate to speed-up translational research of autoimmune diseases

UCLA Heart Transplant Program performs 2,000th heart transplant surgery

LUMC oncologist presents survival data for brentuximab vedotin at 17th EHA Congress

TB research finds body’s own response helps TB bacteria survive

Scientists transplant stem cells from patients with limb-girdle muscular dystrophy into mice

Pediatric Hodgkin lymphoma can be treated without radiation and intensive chemotherapy

Scientists reverse diabetes in mice using stem cells

Magnet guides iron-loaded cells to specific damaged sites in the heart

SIR/TAC combination more effective in preventing GVHD after allogeneic blood cell transplantation

ESCs and iPSCs demonstrate similar survival and neural differentiation capabilities

Poor prognosis for heart transplant patients with restenosis

World-renowned pediatric cardiac surgeon performs 10,000th milestone operation

New analysis finds increase in per-patient operating costs in PCMHs

Deferasirox reduces elevated iron levels in patients with myelodysplastic syndrome

CARHY announces comprehensive hematopoietic stem cell transplant service

Wake Forest Baptist researchers achieve early milestone in lab-engineered kidney project

Structured exercise programmes benefit lung transplant patients

Parents must be considered during expansion of genetic screening programs for newborns

New methods to track stem cells

Largest study to examine impact of gastric sleeve surgery on pre-transplant obese patients

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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